Search Results - "Joshi, Tanuja"
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Structure-based screening of novel lichen compounds against SARS Coronavirus main protease (Mpro) as potentials inhibitors of COVID-19
Published in Molecular diversity (01-08-2021)“…The outbreak of SARS-CoV-2 and deaths caused by it all over the world have imposed great concern on the scientific community to develop potential drugs to…”
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Using Chou’s 5-steps rule to study pharmacophore-based virtual screening of SARS-CoV-2 Mpro inhibitors
Published in Molecular diversity (01-08-2021)“…Recently emerged SARS-CoV-2 is the cause of the ongoing outbreak of COVID-19. It is responsible for the deaths of millions of people and has caused global…”
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3
Development of novel media formulation using rice straw and corn steep liquor for pyruvate production
Published in Biomass conversion and biorefinery (01-08-2023)“…Pyruvate was produced using novel organic macronutrients, pre-treated rice straw and corn steep (CSL) in the media formulation. The results were optimised…”
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Process control of mAb production using multi-actor proximal policy optimization
Published in Digital Chemical Engineering (01-09-2023)“…Monoclonal antibodies (mAb) are biopharmaceutical products that improve human immunity. In this work, we propose a multi-actor proximal policy…”
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In silico screening of potential antidiabetic phytochemicals from Phyllanthus emblica against therapeutic targets of type 2 diabetes
Published in Journal of ethnopharmacology (10-02-2020)“…Phyllanthus emblica Linn. (Syn. Emblica officinalis Gaertn.), has been used to cure many ailments of human beings. Literature survey demonstrates that it has…”
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Molecular docking and molecular dynamics simulation approach to screen natural compounds for inhibition of Xanthomonas oryzae pv. Oryzae by targeting peptide deformylase
Published in Journal of biomolecular structure & dynamics (11-02-2021)“…Xanthomonas oryzae pv. Oryzae (Xoo) causes bacterial leaf blight (BLB) of rice which results in a huge loss in production. Many chemicals are used to control…”
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A Novel Dynamic Just-in-Time Learning Framework for Modeling of Batch Processes
Published in Industrial & engineering chemistry research (28-10-2020)“…A novel dynamic just-in-time (JIT) learning framework is proposed in this paper for the data driven modeling of batch process. In the proposed JIT framework,…”
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8
Molecular dynamics simulation for screening phytochemicals as α-amylase inhibitors from medicinal plants
Published in Journal of biomolecular structure & dynamics (22-11-2021)“…Diabetes mellitus (DM) is a complicated metabolic disorder with several enzymes, including α-amylase and α-glycosidase. The α-amylase is responsible for…”
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9
Twin actor twin delayed deep deterministic policy gradient (TATD3) learning for batch process control
Published in Computers & chemical engineering (01-12-2021)“…•This study explores the feasibility of reinforcement learning (RL) based control of batch process.•In particular, the present study exploits the application…”
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Critical challenges of integrating OPEX strategies with I4.0 technologies in manufacturing SMEs: a few pieces of evidence from developing economies
Published in TQM journal (02-01-2024)“…PurposeThe study proposes to determine the impending challenges to lean integration with Industry 4.0 (I4.0) in manufacturing that aims at achieving desired…”
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Deep-learning based repurposing of FDA-approved drugs against Candida albicans dihydrofolate reductase and molecular dynamics study
Published in Journal of biomolecular structure & dynamics (24-11-2022)“…Candida albicans causes the fatal fungal bloodstream infection in humans called Candidiasis. Most of the Candida species are resistant to the antifungals used…”
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In silico screening of anti-inflammatory compounds from Lichen by targeting cyclooxygenase-2
Published in Journal of biomolecular structure & dynamics (12-08-2020)“…Non-steroidal anti-inflammatory drugs (NSAID) targeting cyclooxygenase-2 are clinically effective. However, they lack anti-thrombotic activity resulting in…”
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13
Identification of Berbamine, Oxyacanthine and Rutin from Berberis asiatica as anti-SARS-CoV-2 compounds: An in silico study
Published in Journal of molecular graphics & modelling (01-12-2021)“…Owing to the shortage of specific medicines, the global pandemic of COVID-19 caused by SARS-CoV-2 has been the greatest challenge for the science community…”
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14
An Approach to Analyze Reliability Indices in Peer-To-Peer Communication Systems
Published in Cybernetics and systems (17-11-2022)“…In this work, the performance of a peer-to-peer (P2P) network has been discussed. As being one of the most promising technology in today's world, P2P systems…”
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15
TASAC: A twin-actor reinforcement learning framework with a stochastic policy with an application to batch process control
Published in Control engineering practice (01-05-2023)“…Due to their complex nonlinear dynamics and batch-to-batch variability, batch processes pose a challenge for process control. Due to the absence of accurate…”
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QSAR modeling and pharmacoinformatics of SARS coronavirus 3C-like protease inhibitors
Published in Computers in biology and medicine (01-07-2021)“…The search for effective treatment against novel coronavirus (COVID-19) remains a global challenge due to controversies on available vaccines. In this study,…”
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Predictive modeling by deep learning, virtual screening and molecular dynamics study of natural compounds against SARS-CoV-2 main protease
Published in Journal of biomolecular structure & dynamics (22-11-2021)“…The whole world is facing a great challenging time due to Coronavirus disease (COVID-19) caused by SARS-CoV-2. Globally, more than 14.6 M people have been…”
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Evaluation of the inhibitory potential of Valproic acid against histone deacetylase of Leishmania donovani and computational studies of Valproic acid derivatives
Published in Journal of biomolecular structure & dynamics (13-08-2023)“…Valproic acid (VA) is a proven inhibitor of human histone deacetylases (HDACs). The homogenous HDAC has been associated with all major human parasitic…”
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Identification of natural inhibitors against Mpro of SARS-CoV-2 by molecular docking, molecular dynamics simulation, and MM/PBSA methods
Published in Journal of biomolecular structure & dynamics (13-04-2022)“…The recent outbreak of SARS-CoV-2 disease, also known as COVID-19, has emerged as a pandemic. The unavailability of specific therapeutic drugs and vaccines…”
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In silico identification of natural fungicide from Melia azedarach against isocitrate lyase of Fusarium graminearum
Published in Journal of biomolecular structure & dynamics (02-09-2021)“…Isocitrate Lyase (ICL) is a crucial enzyme involved in the Glyoxylate pathway, essential for the virulence of several fungal pathogens including Fusarium…”
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