Search Results - "Joshi, Ramila"

Liquid-based three-dimensional tumor models for cancer research and drug discovery by Ham, Stephanie L, Joshi, Ramila, Thakuri, Pradip S, Tavana, Hossein

“…Tumors are three-dimensional tissues where close contacts between cancer cells, intercellular interactions between cancer and stromal cells, adhesion of cancer…”
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Phytochemicals inhibit migration of triple negative breast cancer cells by targeting kinase signaling by Shahi Thakuri, Pradip, Gupta, Megha, Singh, Sunil, Joshi, Ramila, Glasgow, Eric, Lekan, Alexander, Agarwal, Seema, Luker, Gary D, Tavana, Hossein

“…Cell migration and invasion are essential processes for metastatic dissemination of cancer cells. Significant progress has been made in developing new…”
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Engineered Breast Cancer Cell Spheroids Reproduce Biologic Properties of Solid Tumors by Ham, Stephanie L., Joshi, Ramila, Luker, Gary D., Tavana, Hossein

“…Solid tumors develop as 3D tissue constructs. As tumors grow larger, spatial gradients of nutrients and oxygen and inadequate diffusive supply to cells distant…”
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Molecular Analysis of Stromal Cells-Induced Neural Differentiation of Mouse Embryonic Stem Cells by Joshi, Ramila, Buchanan, James Carlton, Paruchuri, Sailaja, Morris, Nathan, Tavana, Hossein

“…Deriving specific neural cells from embryonic stem cells (ESCs) is a promising approach for cell replacement therapies of neurodegenerative diseases. When…”
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Interfacial Tension Effect on Cell Partition in Aqueous Two-Phase Systems by Atefi, Ehsan, Joshi, Ramila, Mann, Jay Adin, Tavana, Hossein

“…Aqueous two-phase systems (ATPS) provide a mild environment for the partition and separation of cells. We report a combined experimental and theoretical study…”
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Stem cell colony interspacing effect on differentiation to neural cells by Joshi, Ramila, Fuller, Brendan, Mosadegh, Bobak, Tavana, Hossein

“…Efforts to enhance the efficiency of neural differentiation of stem cells are primarily focused on exogenous modulation of physical niche parameters such as…”
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Microprinted Stem Cell Niches Reveal Compounding Effect of Colony Size on Stromal Cells‐Mediated Neural Differentiation by Joshi, Ramila, Thakuri, Pradip Shahi, Buchanan, James C., Li, Jun, Tavana, Hossein

“…Microenvironmental factors have a major impact on differentiation of embryonic stem cells (ESCs). Here, a novel phenomenon that size of ESC colonies has a…”
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Micro-Engineering of Embryonic Stem Cells Niche to Regulate Neural Cell Differentiation by Joshi, Ramila

“…Neurodegenerative diseases that are caused by deterioration of nerve cells in the brain and spinal cord affect more than 6 million Americans and cost nearly…”
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Synergistic Inhibition of Kinase Pathways Overcomes Resistance of Colorectal Cancer Spheroids to Cyclic Targeted Therapies by Thakuri, Pradip Shahi, Gupta, Megha, Joshi, Ramila, Singh, Sunil, Tavana, Hossein

“…Cancer cells often adapt to single-agent treatments with chemotherapeutics. Activation of alternative survival pathways is a major mechanism of drug…”
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Microengineered embryonic stem cells niche to induce neural differentiation by Joshi, Ramila, Tavana, Hossein

“…A major challenge in therapeutic use of embryonic stem cells (ESCs) for treating neurodegenerative diseases is creating a niche in vitro for controlled…”
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Colony size effect on neural differentiation of embryonic stem cells microprinted on stromal cells by Joshi, Ramila, Buchanan, James, Tavana, Hossein

“…Controlling cellular microenvironment to induce neural differentiation of embryonic stem cells (ESCs) remains a major challenge. We address this need by…”
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