Search Results - "Joshi, Manjunath B."
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Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death
Published in FEBS letters (16-07-2010)“…Neutrophil interaction with activated endothelial cells (EC) is required for transmigration. We examined consequences of this interaction on NETosis…”
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High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation
Published in FEBS letters (11-07-2013)“…•High glucose impedes and delays NET formation.•Neutrophils from diabetic subjects respond weakly to NETosis.•Hyperglycemia induces a constitutively active…”
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3
He–Ne laser accelerates seed germination by modulating growth hormones and reprogramming metabolism in brinjal
Published in Scientific reports (12-04-2021)“…A plant’s ability to maximize seed germination, growth, and photosynthetic productivity depends on its aptitude to sense, evaluate, and respond to the quality,…”
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Elevated homocysteine levels in type 2 diabetes induce constitutive neutrophil extracellular traps
Published in Scientific reports (04-11-2016)“…Constitutively active neutrophil extracellular traps (NETs) and elevated plasma homocysteine are independent risk factors for Type 2 Diabetes (T2D) associated…”
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Neutrophil (dys)function due to altered immuno-metabolic axis in type 2 diabetes: implications in combating infections
Published in Human cell : official journal of Human Cell Research Society (01-07-2023)“…Metabolic and inflammatory pathways are highly interdependent, and both systems are dysregulated in Type 2 diabetes (T2D). T2D is associated with pre-activated…”
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Differential Gene Expression and Withanolides Biosynthesis During in vitro and ex vitro Growth of Withania somnifera (L.) Dunal
Published in Frontiers in plant science (14-06-2022)“…Ashwagandha ( L. Dunal) is a medicinally important plant with withanolides as its major bioactive compounds, abundant in the roots and leaves. We examined the…”
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Role of Exercise in Pulmonary Hypertension: Evidence from Bench to Bedside
Published in Pulse (01-01-2024)“…Abstract Background: Pulmonary hypertension (PH) is a debilitating condition characterized by elevated pulmonary arterial pressure and progressive vascular…”
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Blue Light-Induced Retinal Neuronal Injury and Amelioration by Commercially Available Blue Light-Blocking Lenses
Published in Life (Basel, Switzerland) (07-02-2022)“…Blue light exposure-induced retinal damage has been extensively studied. Although many in vitro studies have shown the benefits of blue light-blocking lenses…”
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Modulation of neutrophil (dys)function by Ayurvedic herbs and its potential influence on SARS-CoV-2 infection
Published in Journal of ayurveda and integrative medicine (01-01-2022)“…For centuries, traditional medicines of Ayurveda have been in use to manage infectious and non-infectious diseases. The key embodiment of traditional medicines…”
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Redox modulator iron complexes trigger intrinsic apoptosis pathway in cancer cells
Published in iScience (21-06-2024)“…The emergence of multidrug resistance in cancer cells necessitates the development of new therapeutic modalities. One way cancer cells orchestrate energy…”
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Identification of Proteins Associating with Glycosylphosphatidylinositol- Anchored T-Cadherin on the Surface of Vascular Endothelial Cells: Role for Grp78/BiP in T-Cadherin-Dependent Cell Survival
Published in Molecular and Cellular Biology (01-06-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP-dependent lipid uptake and fatty acid synthesis pathways
Published in iScience (18-02-2022)“…Infiltration of arterial intima by foamy macrophages is a hallmark of early atherosclerotic lesions. Here, we investigated the potential role of Ser/Thr…”
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Understanding the effects of Abhraka Bhasma on genotoxicity and its DNA repair potential in mouse model
Published in Journal of ayurveda and integrative medicine (01-03-2023)“…Metal toxicity is of major concern to human health. The metals may modulate molecular mechanisms of various pathways. Rasashastra, the branch of Ayurveda,…”
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Deletion in the A4GALT Gene Associated with Rare “P null” Phenotype: The First Report from India
Published in Transfusion medicine and hemotherapy (01-04-2020)“…Background: The present report illustrates a case with rare “P null” phenotype due to a large deletion in chromosome 22q13.2 and with clinically significant…”
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Effect of Light Emitting Diodes (LED) Exposure on Vitreous Metabolites-Rodent Study
Published in Metabolites (03-01-2023)“…The exposure to blue and white Light emitting diodes (LED) light leads to damage in the visual system with short-term LED light exposure. Chronic exposure,…”
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P-I metalloproteinases and L-amino acid oxidases from Bothrops species inhibit angiogenesis
Published in The journal of venomous animals and toxins including tropical diseases (2021)“…Snake venoms are composed of pharmacologically active proteins that are evolutionarily diverse, stable and specific to targets. Hence, venoms have been…”
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BRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cells
Published in Laboratory investigation (01-12-2012)“…T-cadherin (cadherin 13, H-cadherin, gene name CDH13) has been proposed to act as a tumor-suppressor gene as its expression is significantly diminished in…”
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DNA damage-induced senescence is associated with metabolomic reprogramming in breast cancer cells
Published in Biochimie (01-01-2024)“…Senescence due to exogenous and endogenous stresses triggers metabolic reprogramming and is associated with many pathologies, including cancer. In solid…”
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Comprehensive analysis of regulation of DNA methyltransferase isoforms in human breast tumors
Published in Journal of cancer research and clinical oncology (01-04-2021)“…Significant reprogramming of epigenome is widely described during pathogenesis of breast cancer. Transformation of normal cell to hyperplastic cell and to…”
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Neutrophil sub-types in maintaining immune homeostasis during steady state, infections and sterile inflammation
Published in Inflammation research (01-06-2023)“…Introduction Neutrophils are component of innate immune system and a) eliminate pathogens b) maintain immune homeostasis by regulating other immune cells and…”
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