Search Results - "Joshi, Devyani"

Potential of DPD ((S)-4,5-dihydroxy-2,3-pentanedione) Analogs in Microparticulate Formulation as Vaccine Adjuvants by Joshi, Devyani, Shah, Sarthak, Chbib, Christiane, Uddin, Mohammad N

“…The molecule (S)-4,5-dihydroxy-2,3-pentanedione (DPD) is produced by many different species of bacteria and is involved in bacterial communication. DPD is the…”
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Human immune organoids to decode B cell response in healthy donors and patients with lymphoma by Zhong, Zhe, Quiñones-Pérez, Manuel, Dai, Zhonghao, Juarez, Valeria M., Bhatia, Eshant, Carlson, Christopher R., Shah, Shivem B., Patel, Anjali, Fang, Zhou, Hu, Thomas, Allam, Mayar, Hicks, Sakeenah L., Gupta, Mansi, Gupta, Sneh Lata, Weeks, Ethan, Vagelos, Stephanie D., Molina, Alejandro, Mulero-Russe, Adriana, Mora-Boza, Ana, Joshi, Devyani J., Sekaly, Rafick P., Sulchek, Todd, Goudy, Steven L., Wrammert, Jens, Roy, Krishnendu, Boss, Jeremy M., Coskun, Ahmet F., Scharer, Christopher D., García, Andrés J., Koff, Jean L., Singh, Ankur

“…Antibodies are produced when naive B cells differentiate into plasma cells within germinal centres (GCs) of lymphoid tissues. Patients with B cell lymphoma on…”
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Formulation and Characterization of Microcapsules Encapsulating PC12 Cells as a Prospective Treatment Approach for Parkinson’s Disease by Joshi, Devyani J., Chitre, Neha M., Bansal, Amit, Murnane, Kevin S., D’Souza, Martin J.

“…Parkinson’s disease (PD) is the second most common neurological disorder, associated with decreased dopamine levels in the brain. The goal of this study was to…”
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The Autoinducer N-Octanoyl-L-Homoserine Lactone (C8-HSL) as a Potential Adjuvant in Vaccine Formulations by Shah, Sarthak M, Joshi, Devyani, Chbib, Christiane, Roni, Monzurul A, Uddin, Mohammad N

“…Autoinducers AI-1 and AI-2 play an important role in bacterial quorum sensing (QS), a form of chemical communication between bacteria. The autoinducer…”
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Microneedle Delivery of an Adjuvanted Microparticulate Vaccine Induces High Antibody Levels in Mice Vaccinated against Coronavirus by Vijayanand, Sharon, Patil, Smital, Joshi, Devyani, Menon, Ipshita, Braz Gomes, Keegan, Kale, Akanksha, Bagwe, Priyal, Yacoub, Shadi, Uddin, Mohammad N., D’Souza, Martin J.

“…This ‘proof-of-concept’ study aimed to test the microparticulate vaccine delivery system and a transdermal vaccine administration strategy using dissolving…”
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Zika Vaccine Microparticles (MPs)-Loaded Dissolving Microneedles (MNs) Elicit a Significant Immune Response in a Pre-Clinical Murine Model by Kale, Akanksha, Joshi, Devyani, Menon, Ipshita, Bagwe, Priyal, Patil, Smital, Vijayanand, Sharon, Braz Gomes, Keegan, Uddin, Mohammad N, D'Souza, Martin J

“…Although the global Zika epidemic in 2015-16 fueled vaccine development efforts, there is no approved Zika vaccine or treatment available to date. Current…”
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Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults by Joshi, Devyani, Nyhoff, Lindsay E., Zarnitsyna, Veronika I., Moreno, Alberto, Manning, Kelly, Linderman, Susanne, Burrell, Allison R., Stephens, Kathy, Norwood, Carson, Mantus, Grace, Ahmed, Rafi, Anderson, Evan J., Staat, Mary A., Suthar, Mehul S., Wrammert, Jens

“…As SARS-CoV-2 becomes endemic, it is critical to understand immunity following early-life infection. We evaluated humoral responses to SARS-CoV-2 in 23…”
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Novel microparticulate Zika vaccine induces a significant immune response in a preclinical murine model after intramuscular administration by Kale, Akanksha, Joshi, Devyani, Menon, Ipshita, Bagwe, Priyal, Patil, Smital, Vijayanand, Sharon, Braz Gomes, Keegan, D'Souza, Martin

“…[Display omitted] Despite the detrimental effects associated with Zika infection, there are no approved treatments or vaccines available. To address the need…”
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Potential of DPD Analogs in Microparticulate Formulation as Vaccine Adjuvants by Joshi, Devyani, Shah, Sarthak, Chbib, Christiane, Uddin, Mohammad N

“…The molecule (S)-4,5-dihydroxy-2,3-pentanedione (DPD) is produced by many different species of bacteria and is involved in bacterial communication. DPD is the…”
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Novel ablative laser mediated transdermal immunization for microparticulate measles vaccine by Joshi, Devyani, Gala, Rikhav P., Uddin, Mohammad N., D'Souza, Martin J.

“…[Display omitted] With the need for safe and efficacious vaccines which could be administered via non-invasive procedure, alternatives to traditional…”
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Evaluation of Microparticulate (S)-4,5-Dihydroxy-2,3-pentanedione (DPD) as a Potential Vaccine Adjuvant by Joshi, Devyani, Chbib, Christiane, Uddin, Mohammad N., D’Souza, Martin J.

“…Adjuvants potentiate the immune response against co-inoculated antigens in the vaccine formulation. Based on the mechanism of action, the adjuvants are…”
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Subunit microparticulate vaccine delivery using microneedles trigger significant SARS-spike-specific humoral and cellular responses in a preclinical murine model by Patil, Smital, Vijayanand, Sharon, Joshi, Devyani, Menon, Ipshita, Braz Gomes, Keegan, Kale, Akanksha, Bagwe, Priyal, Yacoub, Shadi, Uddin, Mohammad N., D'Souza, Martin J.

“…[Display omitted] The objective of this “proof-of-concept” study was to evaluate the synergistic effect of a subunit microparticulate vaccine and microneedles…”
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Loss of Pfizer (BNT162b2) Vaccine-Induced Antibody Responses against the SARS-CoV-2 Omicron Variant in Adolescents and Adults by Gupta, Sneh Lata, Mantus, Grace, Manning, Kelly E., Ellis, Madison, Patel, Mit, Ciric, Caroline Rose, Lu, Austin, Turner, Jackson S., O’Halloran, Jane A., Presti, Rachel M., Joshi, Devyani Jaideep, Ellebedy, Ali H., Anderson, Evan J., Rostad, Christina A., Suthar, Mehul S., Wrammert, Jens

“…Emerging variants, especially the recent Omicron variant, and gaps in vaccine coverage threaten mRNA vaccine mediated protection against SARS-CoV-2. While…”
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Anti-SARS-CoV-2 Antibody Levels Associated with COVID-19 Protection in Outpatients Tested for SARS-CoV-2, US Flu VE Network, October 2021-June 2022 by Sumner, Kelsey M, Yadav, Ruchi, Noble, Emma K, Sandford, Ryan, Joshi, Devyani, Tartof, Sara Y, Wernli, Karen J, Martin, Emily T, Gaglani, Manjusha, Zimmerman, Richard K, Talbot, H Keipp, Grijalva, Carlos G, Belongia, Edward A, Chung, Jessie R, Rogier, Eric, Coughlin, Melissa M, Flannery, Brendan

“…We assessed associations between binding antibody (bAb) concentration <5 days of symptom onset and testing positive for COVID-19 among patients in a…”
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Anti–SARS-CoV-2 Antibody Levels Associated With COVID-19 Protection in Outpatients Tested for SARS-CoV-2, US Flu Vaccine Effectiveness Network, October 2021–June 2022 by Sumner, Kelsey M, Yadav, Ruchi, Noble, Emma K, Sandford, Ryan, Joshi, Devyani, Tartof, Sara Y, Wernli, Karen J, Martin, Emily T, Gaglani, Manjusha, Zimmerman, Richard K, Talbot, H Keipp, Grijalva, Carlos G, Belongia, Edward A, Chung, Jessie R, Rogier, Eric, Coughlin, Melissa M, Flannery, Brendan

“…From October 2021 to June 2022, we assessed the association between antibody concentration and COVID-19 illness among patients enrolled in a test-negative…”
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Anti-SARS-CoV-2 Antibody Levels Associated With COVID-19 Protection in Outpatients Tested for SARS-CoV-2, US Flu Vaccine Effectiveness Network, October 2021-June 2022 by Sumner, Kelsey M, Yadav, Ruchi, Noble, Emma K, Sandford, Ryan, Joshi, Devyani, Tartof, Sara Y, Wernli, Karen J, Martin, Emily T, Gaglani, Manjusha, Zimmerman, Richard K, Talbot, H Keipp, Grijalva, Carlos G, Belongia, Edward A, Chung, Jessie R, Rogier, Eric, Coughlin, Melissa M, Flannery, Brendan

“…We assessed associations between binding antibody (bAb) concentration <5 days from symptom onset and testing positive for COVID-19 among patients in a…”
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Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth by Wimmers, Florian, Burrell, Allison R., Feng, Yupeng, Zheng, Hong, Arunachalam, Prabhu S., Hu, Mengyun, Spranger, Sara, Nyhoff, Lindsay E., Joshi, Devyani, Trisal, Meera, Awasthi, Mayanka, Bellusci, Lorenza, Ashraf, Usama, Kowli, Sangeeta, Konvinse, Katherine C., Yang, Emily, Blanco, Michael, Pellegrini, Kathryn, Tharp, Gregory, Hagan, Thomas, Chinthrajah, R. Sharon, Nguyen, Tran T., Grifoni, Alba, Sette, Alessandro, Nadeau, Kari C., Haslam, David B., Bosinger, Steven E., Wrammert, Jens, Maecker, Holden T., Utz, Paul J., Wang, Taia T., Khurana, Surender, Khatri, Purvesh, Staat, Mary A., Pulendran, Bali

“…The dynamics of immunity to infection in infants remain obscure. Here, we used a multi-omics approach to perform a longitudinal analysis of immunity to severe…”
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Zika Vaccine Microparticles Elicit a Significant Immune Response in a Pre-Clinical Murine Model by Kale, Akanksha, Joshi, Devyani, Menon, Ipshita, Bagwe, Priyal, Patil, Smital, Vijayanand, Sharon, Braz Gomes, Keegan, Uddin, Mohammad N, D’Souza, Ma

“…Although the global Zika epidemic in 2015–16 fueled vaccine development efforts, there is no approved Zika vaccine or treatment available to date. Current…”
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Antibody Response to Symptomatic Infection With SARS‐CoV‐2 Omicron Variant Viruses, December 2021–June 2022 by Sandford, Ryan, Yadav, Ruchi, Noble, Emma K., Sumner, Kelsey, Joshi, Devyani, Tartof, Sara Y., Wernli, Karen J., Martin, Emily T., Gaglani, Manjusha, Zimmerman, Richard K., Talbot, H. Keipp, Grijalva, Carlos G., Belongia, Edward A., Carlson, Christina, Coughlin, Melissa, Flannery, Brendan, Pearce, Brad, Rogier, Eric

“…ABSTRACT We describe humoral immune responses in 105 ambulatory patients with laboratory‐confirmed SARS‐CoV‐2 Omicron variant infection. In dried blood spot…”
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