Search Results - "Joshi, Anjali B."

Studies on the mechanism of aspartic acid cleavage and glutamine deamidation in the acidic degradation of glucagon by Joshi, Anjali B, Sawai, Monali, Kearney, William R, Kirsch, Lee E

“…In this study, the polypeptide hormone glucagon was used as a model to investigate the mechanisms of aspartic acid cleavage and glutaminyl deamidation in…”
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The degradation pathways of glucagon in acidic solutions by Joshi, Anjali B, Rus, Elena, Kirsch, Lee E

“…Objective: Glucagon is a 29 amino acid peptide hormone that exhibits degradation via both chemical and physical pathways. The objective of the studies reported…”
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The estimation of glutaminyl deamidation and aspartyl cleavage rates in glucagon by Joshi, Anjali B., Kirsch, Lee E.

“…The major hydrolytic degradation pathways of glucagon under acidic conditions are cleavage at Asp-9, Asp-15, and Asp-21, and deamidation at Gln-3, Gln-20,…”
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The relative rates of glutamine and asparagine deamidation in glucagon fragment 22-29 under acidic conditions by Joshi, Anjali B, Kirsch, Lee E

“…Our objective was to compare the relative rates of asparaginyl and glutaminyl deamidation in fragment 22-29 of the polypeptide hormone glucagon in acidic…”
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Preformulation Studies on the S-Isomer of Oxybutynin Hydrochloride, an Improved Chemical Entity (ICE™) by Luner, Paul E., Kirsch, Lee E., Majuru, Shingai, Oh, Euichaul, Joshi, Anjali B., Wurster, Dale Eric, Redmon, Martin P.

“…(S)-Oxybutynin HCl (S-OXY) is a white crystalline solid powder with an acicular particle morphology. Differential scanning calorimetry (DSC) thermograms…”
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