Search Results - "Joseph Kopchick, John"

Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis by Soendergaard, Christoffer, Kvist, Peter Helding, Thygesen, Peter, Reslow, Mats, Nielsen, Ole Haagen, Kopchick, John Joseph, Holm, Thomas Lindebo

“…Growth hormone (GH) resistance may develop as a consequence of inflammation during conditions such as inflammatory bowel disease, encompassing ulcerative…”
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OR0304 Novel Dual Antagonists Of The Growth Hormone Receptor And The Prolactin Receptor by Basu, Reetobrata, Kopchick, John Joseph

“…Disclosure: R. Basu: None. J.J. Kopchick: None. An excess of the human growth hormone (hGH) is associated with multiple pathophysiology including acromegaly,…”
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THU549 Targeting The Growth Hormone Receptor Attenuates Tumor Exosome Mediated Propagation Of Chemoresistance In Melanoma by Kulkarni, Prateek, Basu, Reetobrata, Bonn, Taylor, Kopchick, John Joseph

“…Disclosure: P. Kulkarni: None. R. Basu: None. T. Bonn: None. J.J. Kopchick: None. Elevated ATP-binding cassette (ABC) transporters in tumor cells resulting in…”
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THU545 Growth Hormone Receptor Antagonist As A Novel Combination Therapy Against Triple Negative Breast Cancer by Mora-Criollo, Patricia, Basu, Reetobrata, Kopchick, John Joseph

“…Disclosure: P. Mora-Criollo: None. R. Basu: None. J.J. Kopchick: None. Triple Negative breast (TNBC) cancer is classified based on the absence of ER-, PR-, and…”
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A Novel Peptide Antagonist of the Human Growth Hormone Receptor by Basu, Reetobrata None, Kopchick, John Joseph

“…The human growth hormone (GH) secreted by the anterior pituitary, binds to its cognate growth hormone receptor (GHR) and regulates longitudinal growth, organ…”
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Effects of Growth Hormone in Human Melanoma Drug Resistance by Arora, Pranay, Basu, Reetobrata, Kopchick, John Joseph

“…Melanoma, an extremely drug resistant form of cancer, displays elevated levels of growth hormone (GH) and growth hormone receptor (GHR) expression. We have…”
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OR05-04 Growth Hormone Receptor Antagonism Markedly Improves Therapeutic Response In Mouse Models Of Melanoma, Liver Cancer, Pancreatic Cancer And Cholangiocarcinoma by Basu, Reetobrata, Kulkarni, Prateek, Ortiz, Silvana Duran, Davis, Emily, Kopchick, John Joseph

“…Disclosure: R. Basu: None. P. Kulkarni: None. S. Duran Ortiz: None. E. Davis: None. J.J. Kopchick: None. A major hurdle in tackling cancer, the second biggest…”
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FRI020 Adipocyte Subpopulations Regulate Growth Hormone-induced Lipolysis And Insulin Resistance by Siyar, Sohana, Huang, Jun, Sharma, Rita, Kopchick, John Joseph, Puri, Vishwajeet, Lee, Kevin Y

“…Disclosure: S. Siyar: None. J. Huang: None. R. Sharma: None. J.J. Kopchick: None. V. Puri: None. K.Y. Lee: None. Growth Hormone (GH) administration has long…”
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SAT665 Effects Of Weight Cycling On Hepatic Protein Carbonylation And Lipid Peroxidation by Djalali-Gomez, Maya Aliyeh, Bogart, Jolie A, Ortiz, Silvana Duran, Berryman, Darlene E, Kopchick, John Joseph, List, Edward Owen

“…Disclosure: M.A. Djalali-Gomez: None. J.A. Bogart: None. S. Duran Ortiz: None. D.E. Berryman: None. J.J. Kopchick: None. E.O. List: None. Over two-thirds of…”
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SAT033 Disruption Of GHR In “Middle Aged” Mice Enhances Insulin Sensitivity And Extends Male Lifespan by Duran-Ortiz, Silvana, Owen List, Edward, Young, Jonathan A, Casey Mathes, Samuel, Basu, Reetobrata, BH Slama, Yosri, Berryman, Darlene E, Joseph Kopchick, John

“…Disclosure: S. Duran-Ortiz: None. E.O. List: None. J.A. Young: None. S.C. Mathes: None. R. Basu: None. Y.B. Slama: None. D.E. Berryman: None. Reduced growth…”
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THU051 GH Resistance And Adipose Tissue: Multispecies Measurement Of Morphology And Transcriptome by Young, Jonathan A, Hinrichs, Arne, Clyde Bell, Stephen Robert, Soneson, Maggie, Geitgey, Delaney K, Wolf, Eckhard, List, Edward Owen, Kopchick, John Joseph, Berryman, Darlene E

“…Disclosure: J.A. Young: None. A. Hinrichs: None. S.R. Bell: None. M. Soneson: None. D.K. Geitgey: None. E. Wolf: None. E.O. List: None. J.J. Kopchick: None…”
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Growth Hormone Receptor Inhibition Sensitizes Human Pancreatic Cancer to Chemotherapy Treatments by Basu, Reetobrata, Kopchick, John Joseph, Ortiz, Silvana Duran, Qian, Yanrong, Kulkarni, Prateek

“…Human growth hormone (GH) and its cognate growth hormone receptor (GHR) have been established to have a distinct role in promoting the progression of several…”
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The Effect of the GH/IGF-1 Axis During Trypanosoma Cruzi Infection by Mora-Criollo, Patricia, Basu, Reetobrata, Qian, Yanrong, Costales, Jaime A, Guevara-Aguirre, Jaime, Grijalva, Mario J, Kopchick, John Joseph

“…Trypanosoma cruzi is the parasite responsible for Chagas disease (CD), that affects 6-8 million people worldwide. CD treatment is limited to two drugs…”
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SUN-LB51 Growth Hormone Deficiency and Resistance Result in Altered Intestinal Gross Anatomy and Morphology in Mice at Adult and Older Adult Timepoints by Kuhn, Jaycie J, Jensen, Elizabeth Ann, Young, Jonathan Alan, Busken, Joshua, List, Edward Owen, Kopchick, John Joseph, Berryman, Darlene E

“…Growth hormone (GH) plays an important role in sustaining intestinal integrity. That is, GH has been shown to decrease intestinal permeability and bacterial…”
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Growth Hormone Receptor Gene Disruption in Mature-Adult Mice Improves Glucose Metabolism and Lifespan in Females by Duran-Ortiz, Silvana, List, Edward O, Bell, Stephen, Basu, Reetobrata, Young, Jonathan, McHugh, Todd, Mathes, Samuel Casey, Funk, Kevin Ray, Qian, Yanrong, Berryman, Darlene E, Kopchick, John Joseph

“…Growth hormone (GH) serves an important role in early and adult life. Reduction of GH action has been shown to increase life span in many species of animals…”
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SAT-281 Chronic, Excess Growth Hormone Action Alters the Development and Aging of the Microbial Community in the Mouse Gut by Jensen, Elizabeth Ann, Jackson, Zachary, Young, Jonathan Alan, Kuhn, Jaycie, Onusko, Maria, Carroll, Ronan K, List, Edward Owen, Murphy, Erin R, Kopchick, John Joseph, Berryman, Darlene E

“…Emerging evidence proposes that the gut microbiome has an vital role in host growth, metabolism and endocrinology. That is, gut microbes impact growth by…”
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Antagonism of Growth Hormone Receptor Suppresses Cancer Growth and Drug Resistance in Mice by Qian, Yanrong, Basu, Reetobrata, Terry, Joseph, Mathes, Samuel Casey, Arnett, Nathan, Smith, Cole, Mendez-Gibson, Isaac, Brittain, Alison, Ortiz, Silvana Duran, Kulkarni, Prateek, Funk, Kevin Ray, Bell, Stephen Robert Clyde, List, Edward Owen, Berryman, Darlene E, Kopchick, John Joseph

“…Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) play important roles in different stages of progression and drug resistance in many types of…”
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BIOSYNTHESIS OF RAUSCHER MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE by KOPCHICK, JOHN JOSEPH

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