Search Results - "Joseph J. H. Ackerman"

Rapid vacuolar sequestration: the horseweed glyphosate resistance mechanism [Erratum: 2010 May, v. 66, no. 5, p. 576] by Ge, Xia, d'Avignon, D. André, Ackerman, Joseph JH, Sammons, R. Douglas

“…BACKGROUND: Glyphosate-resistant (GR) weed species are now found with increasing frequency and threaten the critically important glyphosate weed management…”
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Anti-VEGF Antibodies Mitigate the Development of Radiation Necrosis in Mouse Brain by XIAOYU JIANG, ENGELBACH, John A, GARBOW, Joel R, LIYA YUAN, CATES, Jeremy, FENG GAO, DRZYMALA, Robert E, HALLAHAN, Dennis E, RICH, Keith M, SCHMIDT, Robert E, ACKERMAN, Joseph J. H

“…To quantify the effectiveness of anti-VEGF antibodies (bevacizumab and B20-4.1.1) as mitigators of radiation-induced, central nervous system (brain) necrosis…”
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A Gamma-Knife-Enabled Mouse Model of Cerebral Single-Hemisphere Delayed Radiation Necrosis by Jiang, Xiaoyu, Yuan, Liya, Engelbach, John A, Cates, Jeremy, Perez-Torres, Carlos J, Gao, Feng, Thotala, Dinesh, Drzymala, Robert E, Schmidt, Robert E, Rich, Keith M, Hallahan, Dennis E, Ackerman, Joseph J H, Garbow, Joel R

“…To develop a Gamma Knife-based mouse model of late time-to-onset, cerebral radiation necrosis (RN) with serial evaluation by magnetic resonance imaging (MRI)…”
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Can anti-vascular endothelial growth factor antibody reverse radiation necrosis? A preclinical investigation by Duan, Chong, Perez-Torres, Carlos J., Yuan, Liya, Engelbach, John A., Beeman, Scott C., Tsien, Christina I., Rich, Keith M., Schmidt, Robert E., Ackerman, Joseph J. H., Garbow, Joel R.

“…Anti-vascular endothelial growth factor (anti-VEGF) antibodies are a promising new treatment for late time-to-onset radiation-induced necrosis (RN). We sought…”
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How the body controls brain temperature: the temperature shielding effect of cerebral blood flow by Zhu, Mingming, Ackerman, Joseph J. H, Sukstanskii, Alexander L, Yablonskiy, Dmitriy A

“…Departments of 1 Chemistry, 2 Radiology, 3 Physics, and 4 Internal Medicine, Washington University, St. Louis, Missouri Submitted 14 March 2006 ; accepted in…”
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Body and brain temperature coupling: the critical role of cerebral blood flow by Zhu, Mingming, Ackerman, Joseph J. H, Yablonskiy, Dmitriy A

“…Direct measurements of deep-brain and body-core temperature were performed on rats to determine the influence of cerebral blood flow (CBF) on brain temperature…”
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Intracellular water preexchange lifetime in neurons and astrocytes by Yang, Donghan M., Huettner, James E., Bretthorst, G. Larry, Neil, Jeffrey J., Garbow, Joel R., Ackerman, Joseph J.H.

“…Purpose To determine the intracellular water preexchange lifetime, τi, the “average residence time” of water, in the intracellular milieu of neurons and…”
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Deuterium Magnetic Resonance Spectroscopy Quantifies Tumor Fraction in a Mouse Model of a Mixed Radiation Necrosis / GL261-Glioblastoma Lesion by Song, Kyu-Ho, Ge, Xia, Engelbach, John, Rich, Keith M., Ackerman, Joseph J. H., Garbow, Joel R.

“…Purpose Distinguishing recurrent brain tumor from treatment effects, including late time-to-onset radiation necrosis (RN), presents an on-going challenge in…”
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Rat Brain Global Ischemia–Induced Diffusion Changes Revisited: Biophysical Modeling of the Water and NAA MR “Diffusion Signal” by Spees, William M., Sukstanskii, Alex L., Bretthorst, G. Larry, Neil, Jeffrey J., Ackerman, Joseph J.H.

“…Purpose To assess changes in intracellular diffusion as a mechanism for the reduction in water ADC that accompanies brain injury. Using NAA as a marker of…”
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Are complex DCE‐MRI models supported by clinical data? by Duan, Chong, Kallehauge, Jesper F., Bretthorst, G. Larry, Tanderup, Kari, Ackerman, Joseph J.H., Garbow, Joel R.

“…Purpose To ascertain whether complex dynamic contrast enhanced (DCE) MRI tracer kinetic models are supported by data acquired in the clinic and to determine…”
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Modeling dendrite density from magnetic resonance diffusion measurements by Jespersen, Sune N., Kroenke, Christopher D., Østergaard, Leif, Ackerman, Joseph J.H., Yablonskiy, Dmitriy A.

“…Diffusion-weighted imaging (DWI) provides a noninvasive tool to probe tissue microstructure. We propose a simplified model of neural cytoarchitecture intended…”
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Distinguishing Tumor Admixed in a Radiation Necrosis (RN) Background: 1H and 2H MR With a Novel Mouse Brain-Tumor/RN Model by Ge, Xia, Song, Kyu-Ho, Engelbach, John A., Yuan, Liya, Gao, Feng, Dahiya, Sonika, Rich, Keith M., Ackerman, Joseph J. H., Garbow, Joel R.

“…Purpose Distinguishing radiation necrosis (RN) from recurrent tumor remains a vexing clinical problem with important health-care consequences for…”
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The use of MR-detectable reporter molecules and ions to evaluate diffusion in normal and ischemic brain by Ackerman, Joseph J. H., Neil, Jeffrey J.

“…As a result of the technical challenges associated with distinguishing the MR signals arising from intracellular and extracellular water, a variety of…”
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Irradiation-Modulated Murine Brain Microenvironment Enhances GL261-Tumor Growth and Inhibits Anti-PD-L1 Immunotherapy by Garbow, Joel R, Johanns, Tanner M, Ge, Xia, Engelbach, John A, Yuan, Liya, Dahiya, Sonika, Tsien, Christina I, Gao, Feng, Rich, Keith M, Ackerman, Joseph J H

“…Clinical evidence suggests radiation induces changes in the brain microenvironment that affect subsequent response to treatment. This study investigates the…”
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Sodium ion apparent diffusion coefficient in living rat brain by Goodman, James A., Kroenke, Christopher D., Bretthorst, G. Larry, Ackerman, Joseph J. H., Neil, Jeffrey J.

“…The apparent diffusion coefficient (ADC) of Na+ was determined in live rat brain. The brain extracellular‐to‐intracellular Na+ content ratio is ∼8:2, which is…”
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In memoriam: William T. Dixon (1945–2022) by Ackerman, Joseph J. H.

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Bayesian Modeling of NMR Data: Quantifying Longitudinal Relaxation in Vivo, and in Vitro with a Tissue-Water-Relaxation Mimic (Crosslinked Bovine Serum Albumin) by Meinerz, Kelsey, Beeman, Scott C., Duan, Chong, Bretthorst, G. Larry, Garbow, Joel R., Ackerman, Joseph J. H.

“…Recently, a number of magnetic resonance imaging protocols have been reported that seek to exploit the effect of dissolved oxygen (O 2 , paramagnetic) on the…”
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Toward Distinguishing Recurrent Tumor From Radiation Necrosis: DWI and MTC in a Gamma Knife–Irradiated Mouse Glioma Model by Perez-Torres, Carlos J., PhD, Engelbach, John A., AS, Cates, Jeremy, PhD, Thotala, Dinesh, PhD, Yuan, Liya, PhD, Schmidt, Robert E., MD, PhD, Rich, Keith M., MD, Drzymala, Robert E., PhD, Ackerman, Joseph J.H., PhD, Garbow, Joel R., PhD

“…Purpose Accurate noninvasive diagnosis is vital for effective treatment planning. Presently, standard anatomical magnetic resonance imaging (MRI) is incapable…”
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Specificity of vascular endothelial growth factor treatment for radiation necrosis by Perez-Torres, Carlos J, Yuan, Liya, Schmidt, Robert E, Rich, Keith M, Drzymala, Robert E, Hallahan, Dennis E, Ackerman, Joseph J.H, Garbow, Joel R

“…Abstract Recently, radiation induced necrosis in the brain has been treated using bevacizumab, an anti-VEGF antibody. We validated the VEGF specificity by…”
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Quantification and compensation of eddy-current-induced magnetic-field gradients by Spees, William M., Buhl, Niels, Sun, Peng, Ackerman, Joseph J.H., Neil, Jeffrey J., Garbow, Joel R.

“…[Display omitted] ► Two techniques for quantification of MRI system eddy-current effects are described. ► Bayesian approaches using freely available software…”
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