Search Results - "Joseph Hinnebusch, B"

Yersinia pestis can infect the Pawlowsky glands of human body lice and be transmitted by louse bite by Bland, David M, Long, Dan, Rosenke, Rebecca, Hinnebusch, B Joseph

“…Yersinia pestis, the causative agent of plague, is a highly lethal vector-borne pathogen responsible for killing large portions of Europe's population during…”
Get full text

Silencing urease: A key evolutionary step that facilitated the adaptation of Yersinia pestis to the flea-borne transmission route by Chouikha, Iman, Hinnebusch, B. Joseph

“…The arthropod-borne transmission route of Yersinia pestis , the bacterial agent of plague, is a recent evolutionary adaptation. Yersinia pseudotuberculosis ,…”
Get full text

Antibody Opsonization Enhances Early Interactions between Yersinia pestis and Neutrophils in the Skin and Draining Lymph Node in a Mouse Model of Bubonic Plague by Shannon, Jeffrey G, Hinnebusch, B Joseph

“…Bubonic plague results when is deposited in the skin via the bite of an infected flea. Bacteria then traffic to the draining lymph node (dLN) where they…”
Get full text

Human plague: An old scourge that needs new answers by Vallès, Xavier, Stenseth, Nils Chr, Demeure, Christian, Horby, Peter, Mead, Paul S, Cabanillas, Oswaldo, Ratsitorahina, Mahery, Rajerison, Minoarisoa, Andrianaivoarimanana, Voahangy, Ramasindrazana, Beza, Pizarro-Cerda, Javier, Scholz, Holger C, Girod, Romain, Hinnebusch, B Joseph, Vigan-Womas, Ines, Fontanet, Arnaud, Wagner, David M, Telfer, Sandra, Yazdanpanah, Yazdan, Tortosa, Pablo, Carrara, Guia, Deuve, Jane, Belmain, Steven R, D'Ortenzio, Eric, Baril, Laurence

“…Yersinia pestis, the bacterial causative agent of plague, remains an important threat to human health. Plague is a rodent-borne disease that has historically…”
Get full text

Ecological Opportunity, Evolution, and the Emergence of Flea-Borne Plague by Hinnebusch, B Joseph, Chouikha, Iman, Sun, Yi-Cheng

“…The plague bacillus Yersinia pestis is unique among the pathogenic Enterobacteriaceae in utilizing an arthropod-borne transmission route. Transmission by…”
Get full text

Retracing the Evolutionary Path that Led to Flea-Borne Transmission of Yersinia pestis by Sun, Yi-Cheng, Jarrett, Clayton O., Bosio, Christopher F., Hinnebusch, B. Joseph

“…Yersinia pestis is an arthropod-borne bacterial pathogen that evolved recently from Yersinia pseudotuberculosis, an enteric pathogen transmitted via the…”
Get full text

Comparison of the transmission efficiency and plague progression dynamics associated with two mechanisms by which fleas transmit Yersinia pestis by Bosio, Christopher F, Jarrett, Clayton O, Scott, Dana P, Fintzi, Jonathan, Hinnebusch, B Joseph

“…Yersinia pestis can be transmitted by fleas during the first week after an infectious blood meal, termed early-phase or mass transmission, and again after Y…”
Get full text

A Role for Early-Phase Transmission in the Enzootic Maintenance of Plague by Mitchell, Cedar L, Schwarzer, Ashley R, Miarinjara, Adélaïde, Jarrett, Clayton O, Luis, Angela D, Hinnebusch, B Joseph

“…Yersinia pestis, the bacterial agent of plague, is enzootic in many parts of the world within wild rodent populations and is transmitted by different flea…”
Get full text

Yersinia pestis survival and replication within human neutrophil phagosomes and uptake of infected neutrophils by macrophages by Spinner, Justin L., Winfree, Seth, Starr, Tregei, Shannon, Jeffrey G., Nair, Vinod, Steele‐Mortimer, Olivia, Hinnebusch, B. Joseph

“…Yersinia pestis survives and replicates within PMNs, which are taken up by macrophages in vitro. Yersinia pestis, the bacterial agent of plague, is transmitted…”
Get full text

Dermal neutrophil, macrophage and dendritic cell responses to Yersinia pestis transmitted by fleas by Shannon, Jeffrey G, Bosio, Christopher F, Hinnebusch, B Joseph

“…Yersinia pestis, the causative agent of plague, is typically transmitted by the bite of an infected flea. Many aspects of mammalian innate immune response…”
Get full text

Reevaluation of the Role of Blocked Oropsylla hirsuta Prairie Dog Fleas (Siphonaptera: Ceratophyllidae) in Yersinia pestis (Enterobacterales: Enterobacteriaceae) Transmission by Miarinjara, Adélaïde, Eads, David A., Bland, David M., Matchett, Marc R., Biggins, Dean E., Joseph Hinnebusch, B.

“…Prairie dogs in the western United States experience periodic epizootics of plague, caused by the flea-borne bacterial pathogen Yersinia pestis. An early study…”
Get full text

Infectious blood source alters early foregut infection and regurgitative transmission of Yersinia pestis by rodent fleas by Bland, David M, Jarrett, Clayton O, Bosio, Christopher F, Hinnebusch, B Joseph

“…Fleas can transmit Yersinia pestis by two mechanisms, early-phase transmission (EPT) and biofilm-dependent transmission (BDT). Transmission efficiency varies…”
Get full text

Role of the Yersinia pestis phospholipase D (Ymt) in the initial aggregation step of biofilm formation in the flea by Jarrett, Clayton O, Leung, Jacqueline M, Motoshi, Suzuki, Sturdevant, Daniel E, Zhang, Yixiang, Hoyt, Forrest H, Hinnebusch, B Joseph

“…Transmission of by fleas depends on the formation of condensed bacterial aggregates embedded within a gel-like matrix that localizes to the proventricular…”
Get full text

Depolymerization of β-1,6-N-Acetyl-d-Glucosamine Disrupts the Integrity of Diverse Bacterial Biofilms by ITOH, Yoshikane, XIN WANG, HINNEBUSCH, B. Joseph, PRESTON, James F, ROMEO, Tony

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Poor vector competence of the human flea, Pulex irritans, to transmit Yersinia pestis by Miarinjara, Adélaïde, Bland, David M, Belthoff, James R, Hinnebusch, B. Joseph

“…The human flea, Pulex irritans, is widespread globally and has a long association with humans, one of its principal hosts. Its role in plague transmission is…”
Get full text

Structural engineering of a phage lysin that targets Gram-negative pathogens by Lukacik, Petra, Barnard, Travis J, Keller, Paul W, Chaturvedi, Kaveri S, Seddiki, Nadir, Fairman, James W, Noinaj, Nicholas, Kirby, Tara L, Henderson, Jeffrey P, Steven, Alasdair C, Hinnebusch, B. Joseph, Buchanan, Susan K

“…Bacterial pathogens are becoming increasingly resistant to antibiotics. As an alternative therapeutic strategy, phage therapy reagents containing purified…”
Get full text

Yersinia pestis Rcs Phosphorelay Inhibits Biofilm Formation by Repressing Transcription of the Diguanylate Cyclase Gene hmsT by Sun, Yi-Cheng, Guo, Xiao-Peng, Hinnebusch, B. Joseph, Darby, Creg

“…Yersinia pestis, which causes bubonic plague, forms biofilms in fleas, its insect vectors, as a means to enhance transmission. Biofilm development is…”
Get full text

Feeding Behavior Modulates Biofilm-Mediated Transmission of Yersinia pestis by the Cat Flea, Ctenocephalides felis by Bland, David M, Hinnebusch, B Joseph

“…The cat flea, Ctenocephalides felis, is prevalent worldwide, will parasitize animal reservoirs of plague, and is associated with human habitations in known…”
Get full text

Acquisition of yersinia murine toxin enabled Yersinia pestis to expand the range of mammalian hosts that sustain flea-borne plague by Bland, David M, Miarinjara, Adélaïde, Bosio, Christopher F, Calarco, Jeanette, Hinnebusch, B. Joseph

“…Yersinia murine toxin (Ymt) is a phospholipase D encoded on a plasmid acquired by Yersinia pestis after its recent divergence from a Yersinia…”
Get full text

Molecular and Genetic Mechanisms That Mediate Transmission of Yersinia pestis by Fleas by Hinnebusch, B Joseph, Jarrett, Clayton O, Bland, David M

“…The ability to cause plague in mammals represents only half of the life history of . It is also able to colonize and produce a transmissible infection in the…”
Get full text