Search Results - "Joseph G. Mayo"

Expression of β-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-anticancer drug screen: Correlation with sensitivity to microtubule active agents by NICOLETTI, Maria Ines, VALOTI, Giorgio, GIANNAKAKOU, Paraskevi, ZHIRONG ZHAN, KIM, Jon-Hyeok, LUCCHINI, Valeria, LANDONI, Fabio, MAYO, Joseph G, GIAVAZZI, Raffaella, FOJO, Tito

“…Paclitaxel resistance has been associated with overexpression of P-glycoprotein and alterations involving tubulin. To investigate the clinical relevance of…”
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In vivo cultivation of tumor cells in hollow fibers by Hollingshead, M G, Alley, M C, Camalier, R F, Abbott, B J, Mayo, J G, Malspeis, L, Grever, M R

“…Advancement of potential anti-cancer agents from "discovery" in an in vitro screen to pre-clinical development requires a demonstration of in vivo efficacy in…”
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Evaluation of the Potential Cancer Chemotherapeutic Efficacy of Natural Product Isolates Employing in Vivo Hollow Fiber Tests by Mi, Qiuwen, Lantvit, Daniel, Reyes-Lim, Eulenia, Chai, Heebyung, Zhao, Weimin, Lee, Ik-Soo, Peraza-Sánchez, Sergio, Ngassapa, Olipa, Kardono, Leonardus B. S, Riswan, Soedarsono, Hollingshead, Melinda G, Mayo, Joseph G, Farnsworth, Norman R, Cordell, Geoffrey A, Kinghorn, A. Douglas, Pezzuto, John M

“…The hollow fiber test has been developed for the preliminary in vivo assessment of cancer chemotherapeutic efficacy of selected natural products. Using this…”
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Pervilleine A, a novel tropane alkaloid that reverses the multidrug-resistance phenotype by QIUWEN MI, BAOLIANG CUI, PEZZUTO, John M, SILVA, Gloria L, LANTVIT, Daniel, LIM, Eula, HEEBYUNG CHAI, MIN YOU, HOLLINGSHEAD, Melinda G, MAYO, Joseph G, KINGHORN, A. Douglas

“…P-Glycoprotein-mediated drug efflux can yield a multidrug-resistance (MDR) phenotype that is associated with a poor response to cancer chemotherapy…”
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Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay by Mi, Qiuwen, Cui, Baoliang, Silva, Gloria L, Lantvit, Daniel, Lim, Eula, Chai, Heebyung, Hollingshead, Melinda G, Mayo, Joseph G, Kinghorn, A.Douglas, Pezzuto, John M

“…P-Glycoprotein (Pgp)-mediated drug efflux can yield a multidrug-resistance phenotype that is associated with poor response to cancer chemotherapy. Pervilleines…”
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Growth and chemotherapeutic response of cells in a hollow-fiber in vitro solid tumor model by Casciari, J J, Hollingshead, M G, Alley, M C, Mayo, J G, Malspeis, L, Miyauchi, S, Grever, M R, Weinstein, J N

“…Cancer treatments that appear promising in tissue culture are often less effective in solid tumors, in part because of the proliferative and microenvironmental…”
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Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro by Vince, R, Hua, M, Brownell, J, Daluge, S, Lee, F C, Shannon, W M, Lavelle, G C, Qualls, J, Weislow, O S, Kiser, R

“…Carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir: NSC 614846), a novel nucleoside analog, emerged as a potent and selective anti-HIV agent from a…”
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Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice by MCLEMORE, T. L, EGGLESTON, J. C, SHOEMAKER, R. H, ABBOTT, B. J, BOHLMAN, M. E, LIU, M. C, FINE, D. L, MAYO, J. G, BOYD, M. R

“…The propagation efficiencies, growth patterns, histological appearances, and roentgenographic demonstration of tumors derived from six continuous human…”
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Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay by ALLEY, M. C, SCUDIERO, D. A, MONKS, A, HURSEY, M. L, CZERWINSKI, M. J, FINE, D. L, ABBOTT, B. J, MAYO, J. G, SHOEMAKER, R. H, BOYD, M. R

“…For the past 30 years strategies for the preclinical discovery and development of potential anticancer agents have been based largely upon the testing of…”
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Quantitative structure-activity relations in anticancer agents. Activity of selected nitrosoureas against a solid tumor, the Lewis lung carcinoma by Montgomery, John A, Mayo, Joseph G, Hansch, Corwin

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Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma by Montgomery, John A, McCaleb, George S, Johnston, Thomas P, Mayo, Joseph G, Laster, W. Russell

“…The utility of the Lewis lung carcinoma as a secondary screen for the evaluation of nitrosoureas as anticancer agents has been assessed. The activity of this…”
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Expression of β-Tubulin Isotypes in Human Ovarian Carcinoma Xenografts and in a Sub-Panel of Human Cancer Cell Lines from the NCI-Anticancer Drug Screen by Maria Ines Nicoletti, Giorgio Valoti, Paraskevi Giannakakou, Zhirong Zhan, Jon-Hyeok Kim, Valeria Lucchini, Fabio Landoni, Joseph G. Mayo, Raffaella Giavazzi, Tito Fojo

“…Paclitaxel resistance has been associated with overexpression of P-glycoprotein and alterations involving tubulin. To investigate the clinical relevance of…”
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Novel intrapulmonary model orthotopic propagation of human lung cancers in athymic nude mice by MCLEMORE, T. L, LIU, M. C, BRENNAN, R. H, MCMAHON, J. B, FINE, D. L, EGGLESTON, J. C, MAYO, J. G, BOYD, M. R, BLACKER, P. C, GREGG, M, ALLEY, M. C, ABBOTT, B. J, SHOEMAKER, R. H, BOHLMAN, M. E, LITTERST, C. C, HUBBARD, W. C

“…A major impediment to the study of human lung cancer pathophysiology, as well as to the discovery and development of new specific antitumor agents for the…”
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Establishment of human acute myelogenous leukemia lines secreting interleukin-1 beta in SCID mice by Giavazzi, R, Di Berardino, C, Garofalo, A, Motta, T, Gobbi, A, Scanziani, E, Giudici, G, Galli, M, Mayo, J G, Barbui, T

“…A reproducible in vivo model of human acute myelogenous leukemia (AML) was established in severe combined immunodeficient (SCID) mice. The AML-CL and AML-PS…”
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Practical spontaneous metastasis model for in vivo therapeutic studies using a human melanoma by SHOEMAKER, R. H, DYKES, D, PLOWMAN, J, HARRISON, S. D, GRISWOLD, D. P, ABBOTT, B. J, MAYO, J. G, FODSTAD, O, BOYD, M. R

“…In vivo studies aimed at therapy of spontaneous human tumor metastases have been hampered by the lack of practical experimental models. The LOX amelanotic…”
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Quantitative structure-activity relationships in anticancer agents. Activity of selected nitrosoureas against a solid tumor, the Lewis lung carcinoma by Montgomery, J A, Mayo, J G

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