Search Results - "Joseph Colston, M."

CD4-T-Lymphocyte Interactions with Pneumolysin and Pneumococci Suggest a Crucial Protective Role in the Host Response to Pneumococcal Infection by KADIOGLU, Aras, COWARD, William, COLSTON, M. Joseph, HEWITT, Colin R. A, ANDREW, Peter W

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Deletion of the Mycobacterium tuberculosis pknH Gene Confers a Higher Bacillary Load during the Chronic Phase of Infection in BALB/c Mice by PAPAVINASASUNDARAM, K. G, CHAN, Bosco, CHUNG, Ji-Hae, COLSTON, M. Joseph, DAVIS, Elaine O, AV-GAY, Yossef

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A Heterologous DNA Priming-Mycobacterium bovis BCG Boosting Immunization Strategy Using Mycobacterial Hsp70, Hsp65, and Apa Antigens Improves Protection against Tuberculosis in Mice by FERRAZ, Jose C, STAVROPOULOS, Evangelos, MIN YANG, COADE, Steve, ESPITIA, Clara, LOWRIE, Douglas B, COLSTON, M. Joseph, TASCON, Ricardo E

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Therapeutic Efficacy of High-Dose Intravenous Immunoglobulin in Mycobacterium tuberculosis Infection in Mice by ROY, Eleanor, STAVROPOULOS, Evangelos, JOLLES, Stephen, BRENNAN, John, COADE, Stephen, GRIGORIEVA, Elena, WALKER, Barry, DAGG, Belinda, TASCON, Ricardo E, LOWRIE, Douglas B, COLSTON, M. Joseph

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ABC Transporter Containing a Forkhead-Associated Domain Interacts with a Serine-Threonine Protein Kinase and Is Required for Growth of Mycobacterium tuberculosis in Mice by Curry, Juliet M, Whalan, Rachael, Hunt, Debbie M, Gohil, Kalpesh, Strom, Molly, Rickman, Lisa, Colston, M. Joseph, Smerdon, Stephen J, Buxton, Roger S

“…Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA…”
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RNA Encoding the MPT83 Antigen Induces Protective Immune Responses against Mycobacterium tuberculosis Infection by TIAN XUE, STAVROPOULOS, Evangelos, MIN YANG, RAGNO, Silvia, VORDERMEIER, Martin, CHAMBERS, Mark, HEWINSON, Glyn, LOWRIE, Douglas B, COLSTON, M. Joseph, ASCON, Ricardo E

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Antimycobacterial Calixarenes Enhance Innate Defense Mechanisms in Murine Macrophages and Induce Control of Mycobacterium tuberculosis Infection in Mice by COLSTON, M. Joseph, HAILES, Helen C, STAVROPOULOS, Evangelos, HERVE, Anne C, HERVE, Gwenaelle, GOODWORTH, Kerry J, HILL, Alison M, JENNER, Peter, HART, Philip D, TASCON, Ricardo E

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The AraC Family Transcriptional Regulator Rv1931c Plays a Role in the Virulence of Mycobacterium tuberculosis by FROTA, Cristiane C, PAPAVINASASUNDARAM, K. G, DAVIS, Elaine O, COLSTON, M. Joseph

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A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor by Rickman, Lisa, Scott, Colin, Hunt, Debbie M., Hutchinson, Thomas, Menéndez, M. Carmen, Whalan, Rachael, Hinds, Jason, Colston, M. Joseph, Green, Jeffrey, Buxton, Roger S.

“…Summary Deletion of gene Rv3676 in Mycobacterium tuberculosis coding for a transcription factor belonging to the cAMP receptor protein (CRP) family caused…”
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Genome analysis shows a common evolutionary origin for the dominant strains of Mycobacterium tuberculosis in a UK South Asian community by Menéndez, M. Carmen, Buxton, Roger S, Evans, Jason T, Gascoyne-Binzi, Deborah, Barlow, Rachael E.L, Hinds, Jason, Hawkey, Peter M, Colston, M.J., Dr

“…Summary We have investigated the Mycobacterium tuberculosis strain types present in the South Asian population of the UK, in which tuberculosis is particularly…”
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A recA deletion mutant of Mycobacterium bovis BCG confers protection equivalent to that of wild-type BCG but shows increased genetic stability by Sander, Peter, Böttger, Erik C., Springer, Burkhard, Steinmann, Beate, Rezwan, Mandana, Stavropoulos, Evangelos, Joseph Colston, M.

“…The widely used vaccine against tuberculosis, BCG, shows evidence of genetic instability. It has undergone major genetic rearrangements resulting in deletion…”
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Therapy of tuberculosis in mice by DNA vaccination by Lowrie, Douglas B, Tascon, Ricardo E, Bonato, Vania L. D, Lima, Valeria M. F, Faccioli, Lucia H, Stavropoulos, Evangelos, Colston, M. Joseph, Hewinson, Robert G, Moelling, Karin, Silva, Celio L

“…Mycobacterium tuberculosis continues to kill about 3 million people every year, more than any other single infectious agent. This is attributed primarily to an…”
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The functions of OmpATb, a pore‐forming protein of Mycobacterium tuberculosis by Raynaud, Catherine, Papavinasasundaram, K. G., Speight, Richard A., Springer, Burkhard, Sander, Peter, Böttger, Erik C., Colston, M. Joseph, Draper, Philip

“…Summary The functions of OmpATb, the product of the ompATb gene of Mycobacterium tuberculosis and a putative porin, were investigated by studying a mutant with…”
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A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice by Rickman, Lisa, Saldanha, José W, Hunt, Debbie M, Hoar, Dominic N, Colston, M.Joseph, Millar, Jonathan B.A, Buxton, Roger S

“…Mycobacterium tuberculosis, the causative organism of tuberculosis, encounters oxidative stress during phagocytosis by the macrophage and following macrophage…”
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The Immune Response to Tuberculosis by JOSEPH COLSTON, M.

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Genome structure in the vole bacillus, Mycobacterium microti, a member of the Mycobacterium tuberculosis complex with a low virulence for humans by Frota, Cristiane C, Hunt, Debbie M, Buxton, Roger S, Rickman, Lisa, Hinds, Jason, Kremer, Kristin, van Soolingen, Dick, Colston, M. Joseph

“…1 Division of Mycobacterial Research, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK 2 Department of Medical…”
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Construction and complementation of a recA deletion mutant of Mycobacterium smegmatis reveals that the intein in Mycobacterium tuberculosis recA does not affect RecA function by Papavinasasundaram, K. G., Colston, M. Joseph, Davis, Elaine O.

“…A recA deletion mutant of Mycobacterium smegmatis has been isolated by homologous recombination using a sacB counterselection strategy. Deletion of the recA…”
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The mechanism of upstream activation in the rrnB operon of Mycobacterium smegmatis is different from the Escherichia coli paradigm by Arnvig, Kristine B, Gopal, B, Papavinasasundaram, K. G, Cox, Robert A, Colston, M. Joseph

“…1 Division of Mycobacterial Research, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK 2 Division of Protein Structure,…”
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Determination of DNA sequences required for regulated Mycobacterium tuberculosis RecA expression in response to DNA-damaging agents suggests that two modes of regulation exist by Movahedzadeh, F, Colston, M J, Davis, E O

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A new single-copy mycobacterial plasmid, pMF1, from Mycobacterium fortuitum which is compatible with the pAL5000 replicon by Bachrach, Gilad, Colston, M. Joseph, Bercovier, Herve, Bar-Nir, Dror, Anderson, Colin, Papavinasasundaram, K. G

“…Division of Mycobacterial Research, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK 1 Department of Clinical Microbiology,…”
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