Search Results - "Joseph, Tyler A."
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FEAST: fast expectation-maximization for microbial source tracking
Published in Nature methods (01-07-2019)“…A major challenge of analyzing the compositional structure of microbiome data is identifying its potential origins. Here, we introduce fast…”
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Inference of Population Structure from Time-Series Genotype Data
Published in American journal of human genetics (01-08-2019)“…Sequencing ancient DNA can offer direct probing of population history. Yet, such data are commonly analyzed with standard tools that assume DNA samples are all…”
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Compositional Lotka-Volterra describes microbial dynamics in the simplex
Published in PLoS computational biology (01-05-2020)“…Dynamic changes in microbial communities play an important role in human health and disease. Specifically, deciphering how microbial species in a community…”
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Comparative Population Genomics of African Montane Forest Mammals Support Population Persistence across a Climatic Gradient and Quaternary Climatic Cycles
Published in PloS one (22-09-2015)“…The Eastern Afromontane biodiversity hotspot (EABH) has the highest concentration of biodiversity in tropical Africa, yet few studies have investigated recent…”
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Directional Gaussian Mixture Models of the Gut Microbiome Elucidate Microbial Spatial Structure
Published in mSystems (21-12-2021)“…The gut microbiome is spatially heterogeneous, with environmental niches contributing to the distribution and composition of microbial populations. A recently…”
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Accurate and robust inference of microbial growth dynamics from metagenomic sequencing reveals personalized growth rates
Published in Genome research (01-03-2022)“…Patterns of sequencing coverage along a bacterial genome-summarized by a peak-to-trough ratio (PTR)-have been shown to accurately reflect microbial growth…”
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An Introduction to Whole-Metagenome Shotgun Sequencing Studies
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2021)“…Microbial communities are found across diverse environments, including within and across the human body. As many microbes are unculturable in the lab, much of…”
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Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia
Published in Nature communications (24-02-2020)“…The island of Sardinia has been of particular interest to geneticists for decades. The current model for Sardinia’s genetic history describes the island as…”
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Survey of Ranavirus and Batrachochytrium dendrobatidis in Introduced Frogs in Hawaii, USA
Published in Journal of wildlife diseases (01-07-2019)“…Ranaviruses and the fungus Batrachochytrium dendrobatidis are globally important agents of emerging infectious amphibian diseases. Amphibians on Oahu, the…”
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Methods for Modeling the Dynamics of Microbial Communities
Published 01-01-2021“…Advances in DNA sequencing of microbial communities have revealed a complex relationship between the human microbiome and our health. Community dynamics,…”
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Dissertation -
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Comparative Population Genomics of African Montane Forest Mammals Support Population Persistence across a Climatic Gradient and Quaternary Climatic Cycles: e0131800
Published in PloS one (01-09-2015)“…The Eastern Afromontane biodiversity hotspot (EABH) has the highest concentration of biodiversity in tropical Africa, yet few studies have investigated recent…”
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Journal Article