Search Results - "Joseph, Patricia M"
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Review of the abdominal manifestations of cystic fibrosis in the adult patient
Published in Radiographics (01-05-2006)“…Cystic fibrosis is a common inherited fatal disease. As the life expectancy of affected individuals continues to increase with advances in disease management,…”
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The Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC) trial: Rationale and design of a multi-center, double-blind, placebo-controlled trial of high dose bolus administration of vitamin D3 during acute pulmonary exacerbation of cystic fibrosis
Published in Contemporary clinical trials communications (01-06-2017)“…Abstract Vitamin D deficiency is highly prevalent in children and adults with cystic fibrosis (CF). Recent studies have found an association between vitamin D…”
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Shared Decision-Making Tool for Self-Management of Home Therapies for Patients With Cystic Fibrosis
Published in MDM policy & practice (2017)“…Objective: Patients with cystic fibrosis (CF) undertake time-consuming programs of home therapies. Our objective was to develop a tool to help CF patients…”
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Vitamin D for the Immune System in Cystic Fibrosis (DISC): a double-blind, multicenter, randomized, placebo-controlled clinical trial
Published in The American journal of clinical nutrition (01-03-2019)“…Patients with cystic fibrosis (CF) have increased risk of vitamin D deficiency owing to fat malabsorption and other factors. Vitamin D deficiency has been…”
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A kindred of children with interstitial lung disease
Published in Chest (01-07-2007)“…Childhood interstitial lung disease (ILD) is a spectrum of diseases including many different rare lung conditions. We present a family with an unusual…”
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Consensus statement : Guide to bone health and disease in cystic fibrosis
Published in The journal of clinical endocrinology and metabolism (01-03-2005)Get full text
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Adults with cystic fibrosis: spiritual coping with lifelong disease
Published in Journal of health care chaplaincy (02-04-2020)“…Cystic fibrosis (CF) is a chronic life-shortening disease requiring significant coping. Spiritual belief relates to treatment behaviors. Little is known about…”
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Randomized trial of biofilm testing to select antibiotics for cystic fibrosis airway infection
Published in Pediatric pulmonology (01-02-2011)“…Rationale In cystic fibrosis (CF), conventional antibiotic susceptibility results correlate poorly with clinical outcomes. We hypothesized that biofilm testing…”
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Changes in Mineral Micronutrient Status During and After Pulmonary Exacerbation in Adults With Cystic Fibrosis
Published in Nutrition in clinical practice (01-12-2015)“…Background: Patients with cystic fibrosis (CF) may be at risk for micronutrient depletion, particularly during periods of illness and infection. The purpose of…”
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Using Spirituality After an Adult CF Diagnosis: Cognitive Reframing and Adherence Motivation
Published in Journal of health care chaplaincy (01-07-2012)“…Chronic illness is a significant stressor; the majority of Americans cope utilizing spirituality. Numerous studies demonstrate links between spiritual coping…”
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Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications
Published in Human gene therapy (20-07-2001)“…Cystic fibrosis (CF), an autosomal recessive disorder resulting from mutations in the cystic fibrosis trans-membrane conductance regulator (CFTR) gene, is the…”
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Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium
Published in Human gene therapy (20-07-2001)“…A phase I clinical trial was conducted in which recombinant adenovirus containing the cystic fibrosis trans-membrane regulator (CFTR) (Ad2/CFTR) was…”
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Guide to Bone Health and Disease in Cystic Fibrosis
Published in The journal of clinical endocrinology and metabolism (01-03-2005)“…Cystic fibrosis (CF) is the most common genetic disease within the Caucasian population and leads to premature respiratory failure. Approximately 60,000…”
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Cystic Fibrosis Pulmonary Guidelines: Pulmonary Complications: Hemoptysis and Pneumothorax
Published in American journal of respiratory and critical care medicine (01-08-2010)“…Cystic fibrosis (CF) is a recessive genetic disease characterized by dehydration of the airway surface liquid and impaired mucociliary clearance. As a result,…”
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Inhibitory Effect of Heparin on Serotonin-induced Hyperplasia and Hypertrophy of Smooth Muscle Cells
Published in American journal of respiratory cell and molecular biology (01-07-1997)“…Serotonin (5-HT) produces both hyperplastic and hypertrophic effects on smooth muscle cell (SMC) in culture. Heparin is known to inhibit serum-induced…”
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Case 45-1993: A 23-Year-Old Asthmatic Man with Pulmonary Infiltrates and Hilar Lymphadenopathy
Published in The New England journal of medicine (11-11-1993)“…Presentation of Case A 23-year-old man with asthma was admitted to the hospital because of an increased cough with pulmonary infiltrates. There was a history…”
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Review of the Abdominal Manifestations of Cystic Fibrosis in the Adult Patient1
Published in Radiographics (01-05-2006)“…Cystic fibrosis is a common inherited fatal disease. As the life expectancy of affected individuals continues to increase with advances in disease management,…”
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The role of Na+/H+ exchange and growth factors in pulmonary artery smooth muscle cell proliferation
Published in American journal of respiratory cell and molecular biology (01-02-1996)“…Chronic hypoxia produces pulmonary hypertension, in part because of hypertrophy and hyperplasia of pulmonary artery smooth muscle cells (PA SMC)…”
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Inhibition of hypoxic pulmonary hypertension by heparins of differing in vitro antiproliferative potency
Published in American journal of respiratory and critical care medicine (01-06-1994)“…Heparin inhibits smooth-muscle cell (SMC) growth in vitro and inhibits the development of hypoxic pulmonary hypertension and vascular remodeling in vivo. We…”
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Differential effect of three commercial heparins on Na+/H+ exchange and growth of PASMC
Published in The American journal of physiology (01-02-1996)“…Heparin preparations vary in chemical content and in antiproliferative activity for pulmonary artery smooth muscle cells (PASMC). Intracellular alkalinization…”
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