Search Results - "Joseph, M. K."

Osteosarcoma mechanobiology and therapeutic targets by Shoaib, Zunaira, Fan, Timothy M., Irudayaraj, Joseph M. K.

“…Osteosarcoma is one of the most common primary tumours of the bone, with a 5‐year survival rate of less than 20% after the development of metastases…”
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Epitaxial superlattices with titanium nitride as a plasmonic component for optical hyperbolic metamaterials by Naik, Gururaj V., Saha, Bivas, Liu, Jing, Saber, Sammy M., Stach, Eric A., Irudayaraj, Joseph M. K., Sands, Timothy D., Shalaev, Vladimir M., Boltasseva, Alexandra

“…Titanium nitride (TiN) is a plasmonic material having optical properties resembling gold. Unlike gold, however, TiN is complementary metal oxide…”
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Combined Oral Supplementation of Fish Oil and Quercetin Enhances Neuroprotection in a Chronic Rotenone Rat Model: Relevance to Parkinson’s Disease by Denny Joseph, K. M., Muralidhara

“…While the neuromodulatory efficacy of n-3 polyunsaturated fatty acids present in fish and fish oil (FO) are well known, some evidence in animal models suggests…”
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Enhanced neuroprotective effect of fish oil in combination with quercetin against 3‐nitropropionic acid induced oxidative stress in rat brain by Denny Joseph, K.M., Muralidhara

“…While the beneficial effects of fish oil (FO) supplements on the central nervous system function are well established, few findings have led to the hypothesis…”
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First clinical evaluation of a flexible digital ureteroscope with direct in scope suctioning system (Pusen DISS 7.5Ch): prospective multicentric feasibility study by Nedbal, Carlotta, Yuen, Steffi Kar Kei, Akram, Mahir, Keller, Etienne Xavier, Martínez, Begoña Ballesta, Philip, Joe, Emiliani, Esteban, Li, Joseph K. M., Stracci, Damiano, Gauhar, Vineet, Castellani, Daniele, Somani, Bhaskar Kumar

“…Purpose A new digital single-use flexible ureteroscope, Pusen direct in scope suction (DISS) 7.5Fr (PU3033AH), was evaluated with respect to manoeuvrability,…”
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Multiplexable fluorescence lifetime imaging (FLIM) probes for Abl and Src-family kinases by Jena, Sampreeti, Damayanti, Nur P, Tan, Jackie, Pratt, Erica D, Irudayaraj, Joseph M K, Parker, Laurie L

“…Many commonly employed strategies to map kinase activities in live cells require expression of genetically encoded proteins (e.g. FRET sensors). In this work,…”
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Enhanced Energy Transfer from Nitrogen‐Vacancy Centers to Three‐Dimensional Graphene Heterostructures by Laser Nanoshaping by Liu, Jing, Hu, Yaowu, Kumar, Prashant, Liu, Xingtao, Irudayaraj, Joseph M. K., Cheng, Gary J.

“…Graphene, a well‐studied 2D material, is used to tailor the emission behavior of proximal light emitters by controlling the energy flow to modulate the related…”
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A cross-sectional study on gut microbiota in prostate cancer patients with prostatectomy or androgen deprivation therapy by Li, Joseph K. M., Wang, Lynn L., Wong, Christine Y. P., Chiu, Peter K. F., Teoh, Jeremy Y. C., Kwok, Hilda S. W., Leung, Steven C. H., Wong, Sunny H., Tsui, Stephen K. W., Ng, Chi-Fai

“…Background Androgen deprivation therapy (ADT), either by medical or surgical castration, is the backbone for standard treatment of locally advanced or…”
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Fluorescence Lifetime Imaging of Biosensor Peptide Phosphorylation in Single Live Cells by Damayanti, Nur P., Parker, Laurie L., Irudayaraj, Joseph M. K.

“…Better living through biochemistry: Phosphorylation of a Cy5‐labeled Abl kinase peptide biosensor resulted in an extension of fluorescence lifetime in live…”
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End-of-Life Practices in the Netherlands under the Euthanasia Act by van der Heide, Agnes, Onwuteaka-Philipsen, Bregje D, Rurup, Mette L, Buiting, Hilde M, van Delden, Johannes J.M, Hanssen-de Wolf, Johanna E, Janssen, Anke G.J.M, Pasman, H. Roeline W, Rietjens, Judith A.C, Prins, Cornelis J.M, Deerenberg, Ingeborg M, Gevers, Joseph K.M, van der Maas, Paul J, van der Wal, Gerrit

“…In 1993, the Netherlands established a reporting procedure for euthanasia and physician-assisted suicide, and most physicians who followed the guidelines were…”
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The transition structure of chromatin fibers at the nanoscale probed by cryogenic electron tomography by Zhou, Zhongwu, Li, Kunpeng, Yan, Rui, Yu, Guimei, Gilpin, Christopher J, Jiang, Wen, Irudayaraj, Joseph M K

“…The naked DNA inside the nucleus interacts with proteins and RNAs forming a higher order chromatin structure to spatially and temporally control transcription…”
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Designing a Green Library in Alignment with the UN's Sustainable Development Goal: a Case Study of Rajagiri Business School Library, Kerala, India by Vijesh, P.V., Chopade, Varsha, Joy, Varghese, M K, Joseph

“…Abstract Libraries play an essential role in fostering sustainable development by providing equal access to information. Since the beginning of the 1990s,…”
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Multiplex single‐cell quantification of rare RNA transcripts from protoplasts in a model plant system by Kadam, Ulhas S., Schulz, Burkhard, Irudayaraj, Joseph M.K.

“…Summary Here we demonstrate multiplex and simultaneous detection of four different rare RNA species from plant, Arabidopsis thaliana, using surface‐enhanced…”
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High mortality in adults hospitalized for active tuberculosis in a low HIV prevalence setting by Lui, Grace, Wong, Rity Y K, Li, Florence, Lee, May K P, Lai, Raymond W M, Li, Timothy C M, Kam, Joseph K M, Lee, Nelson

“…This study aims to evaluate the outcomes of adults hospitalized for tuberculosis in a higher-income region with low HIV prevalence. A retrospective cohort…”
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Nanoscale histone localization in live cells reveals reduced chromatin mobility in response to DNA damage by Liu, Jing, Vidi, Pierre-Alexandre, Lelièvre, Sophie A, Irudayaraj, Joseph M K

“…Nuclear functions including gene expression, DNA replication and genome maintenance intimately rely on dynamic changes in chromatin organization. The movements…”
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Fish oil prophylaxis attenuates rotenone-induced oxidative impairments and mitochondrial dysfunctions in rat brain by Denny Joseph, K.M., Muralidhara, Mura

“…► Fish oil (FO) modulates rat brain oxidative markers. ► FO attenuates Rotenone (ROT)-induced oxidative/mitochondrial dysfunction. ► FO caused no alterations…”
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Single-molecule tools elucidate H2A.Z nucleosome composition by Chen, Jiji, Miller, Andrew, Kirchmaier, Ann L, Irudayaraj, Joseph M K

“…Although distinct epigenetic marks correlate with different chromatin states, how they are integrated within single nucleosomes to generate combinatorial…”
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Acute, subacute and subchronic safety assessment of betalains rich Rivina humilis L. berry juice in rats by Khan, Mohammad Imtiyaj, Denny Joseph, K.M., Muralidhara, Ramesh, H.P., Giridhar, P., Ravishankar, G.A.

“…► Rivina humilis L. berry juice is potential source of betalains pigment. ► Acute, subacute and subchronic safety assessment of the juice was conducted in…”
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Chromatin hierarchical branching visualized at the nanoscale by electron microscopy by Zhou, Zhongwu, Yan, Rui, Jiang, Wen, Irudayaraj, Joseph M. K

“…Chromatin is spatially organized in a hierarchical manner by virtue of single nucleosomes condensing into higher order chromatin structures, conferring various…”
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Kinase phosphorylation monitoring with i-motif DNA cross-linked SERS probes by Ren, Wen, Damayanti, Nur P, Wang, Xiaolei, Irudayaraj, Joseph M K

“…We propose an ultrasensitive SERS-based peptide biosensor platform to monitor phosphorylation catalyzed by kinase in a dynamic format. The developed SERS…”
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