Search Results - "Joseph, Christelle"

Elevation of Urinary 2‐Hydroxyglutarate in IDH‐Mutant Glioma by Fathi, Amir T., Nahed, Brian V., Wander, Seth A., Iafrate, A. John, Borger, Darrell R., Hu, Ranliang, Thabet, Ashraf, Cahill, Daniel P., Perry, Ashley M., Joseph, Christelle P., Muzikansky, Alona, Chi, Andrew S.

“…Background. Recurrent mutations in the isocitrate dehydrogenase 1 (IDH1) and IDH2 genes, which are frequent in gliomas, result in marked accumulation of the…”
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Early infectious complications among patients treated with induction compared to hypomethylating therapy for acute myeloid leukemia by Jalbut, Marla M., Brunner, Andrew M., Amrein, Philip C., Ballen, Karen K., Hobbs, Gabriela S., Perry, Ashley M., Joseph, Christelle P., Fathi, Amir T.

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Involuntary Autobiographical Memory in Alzheimer's Disease: A Double-Edged Way of Remembering the Past? by Allé, Mélissa C, Joseph, Christelle, Antoine, Pascal

“…Alzheimer's disease (AD) is characterized by severe memory alterations, affecting especially memories of personal past events. Until now, autobiographical…”
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Isocitrate dehydrogenase 1 and 2 mutations, 2‐hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia by Brunner, Andrew M., Neuberg, Donna S., Wander, Seth A., Sadrzadeh, Hossein, Ballen, Karen K., Amrein, Philip C., Attar, Eyal, Hobbs, Gabriela S., Chen, Yi‐Bin, Perry, Ashley, Connolly, Christine, Joseph, Christelle, Burke, Meghan, Ramos, Aura, Galinsky, Ilene, Yen, Katharine, Yang, Hua, Straley, Kimberly, Agresta, Sam, Adamia, Sophia, Borger, Darrell R., Iafrate, Anthony, Graubert, Timothy A., Stone, Richard M., Fathi, Amir T.

“…Background Acute myeloid leukemia (AML) cells harboring mutations in isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) produce the…”
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Cabozantinib is well tolerated in acute myeloid leukemia and effectively inhibits the resistance‐conferring FLT3/tyrosine kinase domain/F691 mutation by Fathi, Amir T., Blonquist, Traci M., Hernandez, Daniela, Amrein, Philip C., Ballen, Karen K., McMasters, Malgorzata, Avigan, David E., Joyce, Robin, Logan, Emma K., Hobbs, Gabriela, Brunner, Andrew M., Joseph, Christelle, Perry, Ashley M., Burke, Meghan, Behnan, Tanya, Foster, Julia, Bergeron, Meghan K., Moran, Jenna A., Ramos, Aura Y., Som, Tina T., Rae, Jessica, Fishman, Kaitlyn M., McGregor, Kristin L., Connolly, Christine, Neuberg, Donna S., Levis, Mark J.

“…BACKGROUND Cabozantinib, a tyrosine kinase inhibitor of FMS‐like tyrosine kinase 3 (FLT3), MET, AXL, vascular endothelial growth factor receptor, and KIT, is…”
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Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia by Fathi, Amir T, Wander, Seth A, Blonquist, Traci M, Brunner, Andrew M, Amrein, Philip C, Supko, Jeffrey, Hermance, Nicole M, Manning, Amity L, Sadrzadeh, Hossein, Ballen, Karen K, Attar, Eyal C, Graubert, Timothy A, Hobbs, Gabriela, Joseph, Christelle, Perry, Ashley M, Burke, Meghan, Silver, Regina, Foster, Julia, Bergeron, Meghan, Ramos, Aura Y, Som, Tina T, Fishman, Kaitlyn M, McGregor, Kristin L, Connolly, Christine, Neuberg, Donna S, Chen, Yi-Bin

“…Aberrant expression of aurora kinase A is implicated in the genesis of various neoplasms, including acute myeloid leukemia. Alisertib, an aurora A kinase…”
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A Phase I Study of the Multi-Targeted Tyrosine Kinase Inhibitor Cabozantinib in Patients with Acute Myeloid Leukemia by Fathi, Amir T., Blonquist, Traci M., Levis, Mark J., Hernandez, Daniela, Ballen, Karen K., Avigan, David E., Joyce, Robin, McMasters, Malgorzata, Logan, Emma, Hobbs, Gabriela S., Brunner, Andrew M., Connolly, Christine, Perry, Ashley M., Joseph, Christelle, Som, Tina T., Ramos, Aura Y., Neuberg, Donna S., Amrein, Philip C.

“…Cabozantinib is a multi-targeted tyrosine kinase inhibitor (TKI) of FLT3, MET, AXL, VEGFR, and KIT, all of which are implicated in the pathogenesis of acute…”
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Infectious complications in AML patients treated with induction vs. hypomethylating therapy by Jalbut, Marla M, Brunner, Andrew Mark, Amrein, Philip C., Attar, Eyal C., Ballen, Karen K., Hobbs, Gabriela, Perry, Ashley M., Joseph, Christelle P., Neuberg, Donna S., Fathi, Amir Tahmasb

“…Abstract only…”
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Use of 2HG Levels in the Serum, Urine, or Bone Marrow to Predict IDH Mutations in Adults with Acute Myeloid Leukemia by Brunner, Andrew M., Neuberg, Donna S, Wander, Seth A., Sadrzadeh, Hossein, Ballen, Karen K., Amrein, Philip C., Hobbs, Gabriela S., Chen, Yi-Bin, Perry, Ashley M., Joseph, Christelle, Burke, Meghan E., Ramos, Aura Y, Silver, Regina, Galinsky, Ilene, Adamia, Sophia, Borger, Darrell, Iafrate, Anthony J, Stone, Richard M., Fathi, Amir T.

“…Mutations in genes encoding the isocitrate dehydrogenase 1/2 (IDH 1/2) enzymes increase production of the oncometabolite 2-hydroxyglutarate (2HG), resulting in…”
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A Phase I Study of the Aurora a Kinase Inhibitor Alisertib in Combination with 7+3 Induction Chemotherapy in Patients with Acute Myeloid Leukemia by Fathi, Amir T., Wander, Seth A., Blonquist, Traci M., Ballen, Karen K., Attar, Eyal C., McAfee, Steven L., Chen, Yi-Bin, Graubert, Timothy A., Brunner, Andrew M., Joseph, Christelle, Perry, Ashley M., Burke, Meghan, Silver, Regina, Ramos, Aura Y., Connolly, Christine, Neuberg, Donna S., Amrein, Philip C.

“…The aurora kinases play an essential role in regulating mitosis and cell division. Over-expression of aurora kinases A and B has been associated with poor-risk…”
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