Search Results - "Joseph, A. A."

Lanmodulin: A Highly Selective Lanthanide-Binding Protein from a Lanthanide-Utilizing Bacterium by Cotruvo, Joseph A, Featherston, Emily R, Mattocks, Joseph A, Ho, Jackson V, Laremore, Tatiana N

“…Lanthanides (Lns) have been shown recently to be essential cofactors in certain enzymes in methylotrophic bacteria. Here we identify in the model methylotroph,…”
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2017 WHO Guidelines for Drinking Water Quality: First Addendum to the Fourth Edition by COTRUVO, JOSEPH A.

“…Drinking water guidelines issued by the World Health Organization—serving as a framework for the water quality standards of many countries—were updated in…”
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Lysosomal acidification mechanisms by Mindell, Joseph A

“…Lysosomes, the terminal organelles on the endocytic pathway, digest macromolecules and make their components available to the cell as nutrients. Hydrolytic…”
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Scientific and ethical basis for social-distancing interventions against COVID-19 by Lewnard, Joseph A, Lo, Nathan C

“…During the 2003 severe acute respiratory syndrome coronavirus (SARS-CoV) outbreak in Singapore, numerous non-pharmaceutical interventions were implemented…”
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Hyperferritinemia and inflammation by Kernan, Kate F, Carcillo, Joseph A

“…Understanding of ferritin biology has traditionally centered on its role in iron storage and homeostasis, with low ferritin levels indicative of deficiency and…”
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A Selective, Protein-Based Fluorescent Sensor with Picomolar Affinity for Rare Earth Elements by Mattocks, Joseph A, Ho, Jackson V, Cotruvo, Joseph A

“…Sensitive yet rapid methods for detection of rare earth elements (REEs), including lanthanides (Lns), would facilitate mining and recycling of these elements…”
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Biological, biomolecular, and bio-inspired strategies for detection, extraction, and separations of lanthanides and actinides by Mattocks, Joseph A, Cotruvo, Joseph A

“…Lanthanides and actinides are elements of ever-increasing technological importance in the modern world. However, the similar chemical and physical properties…”
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The Chemistry of Lanthanides in Biology: Recent Discoveries, Emerging Principles, and Technological Applications by Cotruvo, Joseph A

“…The essential biological role of rare earth elements lay hidden until the discovery in 2011 that lanthanides are specifically incorporated into a bacterial…”
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The Impact of Anthropogenic Land Use and Land Cover Change on Regional Climate Extremes by Findell, Kirsten L, Berg, Alexis, Gentine, Pierre, Krasting, John P, Lintner, Benjamin R, Malyshev, Sergey, Jr, Joseph A Santanello, Shevliakova, Elena

“…Recent research highlights the role of land surface processes in heat waves, droughts, and other extreme events. Here we use an earth system model (ESM) from…”
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A hypothesized role for dysregulated bradykinin signaling in COVID‐19 respiratory complications by Roche, Joseph A., Roche, Renuka

“…As of April 20, 2020, over time, the COVID‐19 pandemic has resulted in 157 970 deaths out of 2 319 066 confirmed cases, at a Case Fatality Rate of ~6.8%. With…”
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Imbalance in the game of T cells: What can the CD4/CD8 T-cell ratio tell us about HIV and health? by McBride, Joseph A, Striker, Rob

“…In a population study of solid neoplasms, an inverted CD4/CD8 ratio is associated with metastatic disease as compared with cancer patients without metastasis…”
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Bridging Hydrometallurgy and Biochemistry: A Protein-Based Process for Recovery and Separation of Rare Earth Elements by Dong, Ziye, Mattocks, Joseph A, Deblonde, Gauthier J.-P, Hu, Dehong, Jiao, Yongqin, Cotruvo, Joseph A, Park, Dan M

“…The extraction and subsequent separation of individual rare earth elements (REEs) from REE-bearing feedstocks represent a challenging yet essential task for…”
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Prevalence and trends in obesity and severe obesity among children in the United States, 1999-2012 by Skinner, Asheley Cockrell, Skelton, Joseph A

“…Childhood obesity is the focus of public health efforts and accurate estimates of the prevalence and severity of obesity are needed for policy decisions and…”
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Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing by Dimitri, Alexander, Herbst, Friederike, Fraietta, Joseph A

“…Chimeric Antigen Receptor (CAR) T-cells represent a breakthrough in personalized cancer therapy. In this strategy, synthetic receptors comprised of antigen…”
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NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR by Yoshino, Jun, Baur, Joseph A., Imai, Shin-ichiro

“…Research on the biology of NAD+ has been gaining momentum, providing many critical insights into the pathogenesis of age-associated functional decline and…”
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NF-κB and the link between inflammation and cancer by DiDonato, Joseph A., Mercurio, Frank, Karin, Michael

“…The nuclear factor‐κB (NF‐κB) transcription factor family has been considered the central mediator of the inflammatory process and a key participant in innate…”
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Synthetic fluorescent probes for studying copper in biological systems by Cotruvo, Jr, Joseph A, Aron, Allegra T, Ramos-Torres, Karla M, Chang, Christopher J

“…The potent redox activity of copper is required for sustaining life. Mismanagement of its cellular pools, however, can result in oxidative stress and damage…”
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Behind the Scenes: The Corporate Governance Preferences of Institutional Investors by McCAHERY, JOSEPH A., SAUTNER, ZACHARIAS, STARKS, LAURA T.

“…We survey institutional investors to better understand their role in the corporate governance of firms. Consistent with a number of theories, we document…”
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The NLRC4 Inflammasome by Duncan, Joseph A., Canna, Scott W.

“…Summary 15 years ago, the fundamental biology of an inflammatory signaling complex eventually dubbed “the inflammasome” began to unravel in chronologic…”
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Targeting signalling pathways and the immune microenvironment of cancer stem cells — a clinical update by Clara, Joseph A., Monge, Cecilia, Yang, Yingzi, Takebe, Naoko

“…Cancer stem cells (CSCs) have important roles in tumour development, relapse and metastasis; the intrinsic self-renewal characteristics and tumorigenic…”
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