Search Results - "Jose, Marco V."

Natural History of DNA-Dependent DNA Polymerases: Multiple Pathways to the Origins of DNA by de Farias, Sávio Torres, Furtado, Ariadne Nobrega Marinho, Dos Santos Junior, Ariosvaldo Pereira, José, Marco V

“…One of the major evolutionary transitions that led to DNA replacing RNA as the primary informational molecule in biological systems is still the subject of an…”
Get full text

A Proposal for the RNAome at the Dawn of the Last Universal Common Ancestor by Palacios-Pérez, Miryam, José, Marco V

“…From the most ancient RNAs, which followed an RNY pattern and folded into small hairpins, modern RNA molecules evolved by two different pathways, dubbed…”
Get full text

A Proposal of the Ur-RNAome by Palacios-Pérez, Miryam, José, Marco V

“…It is widely accepted that the earliest RNA molecules were folded into hairpins or mini-helixes. Herein, we depict the 2D and 3D conformations of those…”
Get full text

Genomic signatures in viral sequences by in-frame and out-frame mutual information by Serrano-Solís, Víctor, Cocho, Germinal, José, Marco V.

“…In order to understand the unique biology of viruses, we use the Mutual Information Function (MIF) to characterize 792 viral sequences comprising 458 viral…”
Get full text

Multivariate Entropy Characterizes the Gene Expression and Protein-Protein Networks in Four Types of Cancer by Juarez-Flores, Angel, Jose, Marco V

“…There is an important urgency to detect cancer at early stages to treat it, to improve the patients' lifespans, and even to cure it. In this work, we…”
Get full text

How to eliminate taeniasis/cysticercosis: porcine vaccination and human chemotherapy (Part 2) by Sánchez-Torres, Norma Y, Bobadilla, Juan R, Laclette, Juan P, José, Marco V

“…The application of effective vaccines against pig cysticercosis and mass chemotherapy against pig cysticercosis and human taeniasis have shown the feasibility…”
Get full text

On the Uniqueness of the Standard Genetic Code by Zamudio, Gabriel S, José, Marco V

“…In this work, we determine the biological and mathematical properties that are sufficient and necessary to uniquely determine both the primeval RNY (purine-any…”
Get full text

Peptidyl Transferase Center and the Emergence of the Translation System by Torres de Farias, Savio, Gaudêncio Rêgo, Thais, José, Marco V

“…In this work, the three-dimensional (3D) structure of the ancestral Peptidyl Transferase Center (PTC) built by concatamers of ancestral sequences of tRNAs was…”
Get full text

Evolution of transfer RNA and the origin of the translation system by de Farias, Savio T, do Rêgo, Thaís G, José, Marco V

Get full text

Flow of Information during an Evolutionary Process: The Case of Influenza A Viruses by Marco V. José, Víctor Serrano-Solís

“…The hypothesis that Mutual Information (MI) dendrograms of influenza A viruses reflect informational groups generated during viral evolutionary processes is…”
Get full text

Is it possible that cells have had more than one origin? by de Farias, Sávio Torres, Jose, Marco V., Prosdocimi, Francisco

“…Cells occupy a prominent place in the history of life in Earth. The central role of cellular organization can be understood by the fact that “cellular life” is…”
Get full text

Novel gene signatures for stage classification of the squamous cell carcinoma of the lung by Juarez-Flores, Angel, Zamudio, Gabriel S., José, Marco V.

“…The squamous cell carcinoma of the lung (SCLC) is one of the most common types of lung cancer. As GLOBOCAN reported in 2018, lung cancer was the first cause of…”
Get full text

Scaling properties and symmetrical patterns in the epidemiology of rotavirus infection by Jose, Marco V, Bishop, Ruth F

“…This paper makes use of epidemiological data on rotavirus infection in young children admitted to hospital in Melbourne, Australia from 1977 to 2000. Several…”
Get full text

Origin of the 16S Ribosomal Molecule from Ancestor tRNAs by de Farias, Savio Torres, Rêgo, Thais Gaudêncio, José, Marco V.

“…We tested the hypothesis that concatemers of ancestral tRNAs gave rise to the 16S ribosomal RNA. We built an ancestral sequence of proto-tRNAs that showed a…”
Get full text

Origin and Evolution of RNA-Dependent RNA Polymerase by de Farias, Savio T, Dos Santos Junior, Ariosvaldo P, Rêgo, Thais G, José, Marco V

“…RNA-dependent RNA polymerases (RdRp) are very ancient enzymes and are essential for all viruses with RNA genomes. We reconstruct the origin and evolution of…”
Get full text

From RNA to DNA: Insights about the transition of informational molecule in the biological systems based on the structural proximity between the polymerases by Pereira dos Santos Junior, Ariosvaldo, José, Marco V., Torres de Farias, Sávio

“…Structural relations in an evolutionary context of polymerases is crucial to gain insights into the transition from an RNA world to a Ribonucleoprotein world…”
Get full text

Anticipation of ventricular tachyarrhythmias by a novel mathematical method: Further insights towards an early warning system in implantable cardioverter defibrillators by Zamudio, Gabriel S, Márquez, Manlio F, José, Marco V

“…Implantable cardioverter defibrillators (ICD) are the most effective therapy to terminate malignant ventricular arrhythmias (VA) and therefore to prevent…”
Get full text

Neutral evolution test of the spike protein of SARS-CoV-2 and its implications in the binding to ACE2 by López-Cortés, Georgina I., Palacios-Pérez, Miryam, Zamudio, Gabriel S., Veledíaz, Hannya F., Ortega, Enrique, José, Marco V.

“…As the SARS-CoV-2 has spread and the pandemic has dragged on, the virus continued to evolve rapidly resulting in the emergence of new highly transmissible…”
Get full text

Identity Elements of tRNA as Derived from Information Analysis by Zamudio, Gabriel S., José, Marco V.

“…The decipherment of the tRNA’s operational code, known as the identity problem, requires the location of the sites in the tRNA structure that are involved in…”
Get full text

The Ancient History of Peptidyl Transferase Center Formation as Told by Conservation and Information Analyses by Prosdocimi, Francisco, Zamudio, Gabriel S., Palacios-Pérez, Miryam, Torres de Farias, Sávio, V. José, Marco

“…The peptidyl transferase center (PTC) is the catalytic center of the ribosome and forms part of the 23S ribosomal RNA. The PTC has been recognized as the…”
Get full text