Search Results - "Jose, Josemin"
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Hindlimb unloading induces time-dependent disruption of testicular histology in mice
Published in Scientific reports (18-10-2022)“…Mechanical unloading of the body in the hindlimb unloaded (HU) mice induces pathology in multiple organs, but the effects on testes are poorly characterized…”
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Mesenchymal stem cell transplant as an intervention to ameliorate disuse-induced muscle atrophy in a mouse model of simulated microgravity
Published in Acta astronautica (01-01-2025)“…The hindlimb unloaded (HU) mouse model exhibits disuse-induced muscle atrophy. However, effective interventions remain elusive. We investigated the therapeutic…”
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Journal Article -
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Pharmacological inhibition of endoplasmic reticulum stress mitigates testicular pathology in a mouse model of simulated microgravity
Published in Acta astronautica (01-03-2023)“…Simulated microgravity during hindlimb unloaded (HU) induces multi-organ pathologies in mice, including testicular dysfunction. However, a detailed…”
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Journal Article -
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Pharmacological inhibition of ER stress mitigates testicular pathology in hind‐limb unloaded mice
Published in The FASEB journal (01-05-2022)“…Reduced physical activity and cephalic fluid shift are common occurrences in prolonged bed rest and space flight, and can lead to testicular dysfunction…”
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Journal Article