Search Results - "Josan, Amandeep S"
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A cross-sectional study to assess the clinical utility of modern visual function assessments in patients with inherited retinal disease: a mixed methods observational study protocol
Published in BMC ophthalmology (24-05-2023)“…Treatment options for patients with inherited retinal disease are limited, although research into novel therapies is underway. To ensure the success of future…”
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Choroideremia: The Endpoint Endgame
Published in International journal of molecular sciences (01-09-2023)“…Choroideremia is an X-linked retinal degeneration resulting from the progressive, centripetal loss of photoreceptors and choriocapillaris, secondary to the…”
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Structural and Functional Characteristics of Color Vision Changes in Choroideremia
Published in Frontiers in neuroscience (07-10-2021)“…Color vision is considered a marker of cone function and its assessment in patients with retinal pathology is complementary to the assessments of spatial…”
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A Network Meta-Analysis of Retreatment Rates following Bevacizumab, Ranibizumab, Aflibercept, and Laser for Retinopathy of Prematurity
Published in Ophthalmology (Rochester, Minn.) (01-12-2022)“…To compare bevacizumab, ranibizumab, aflibercept, and laser treatment as primary therapies for retinopathy of prematurity (ROP) in terms of retreatment rate…”
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Low luminance visual acuity as a clinical measure and clinical trial outcome measure: a scoping review
Published in Ophthalmic & physiological optics (01-03-2021)“…Purpose The measurement of standard visual acuity (VA) is the most well‐known part of any ophthalmic examination to indicate visual function. Despite this, it…”
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Scotopic microperimetry: evolution, applications and future directions
Published in Clinical and experimental optometry (17-11-2022)“…For many inherited and acquired retinal diseases, reduced night vision is a primary symptom. Despite this, the clinical testing options for spatially resolved…”
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Investigating the impact of asymmetric macular sensitivity on visual acuity chart reading in choroideremia
Published in Ophthalmic & physiological optics (01-09-2024)“…Degeneration in choroideremia, unlike typical centripetal photoreceptor degenerations, is centred temporal to the fovea. Once the fovea is affected, the nasal…”
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Establishing Clinical Trial Endpoints in Selecting Patients for RPGR Retinal Gene Therapy
Published in Translational vision science & technology (03-09-2024)“…Clinical trials for X-linked retinitis pigmentosa (RP) often assess retinal structure using optical coherence tomography (OCT) and function using…”
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Exploring Scotopic Microperimetry as an Outcome Measure in Choroideremia
Published in Translational vision science & technology (30-09-2024)“…Choroideremia is an X-linked outer retinal degeneration. Early symptoms include nyctalopia and progressive visual field loss, but visual acuity is preserved…”
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Microperimetry as an Outcome Measure in RPGR-associated Retinitis Pigmentosa Clinical Trials
Published in Translational vision science & technology (01-06-2023)“…To explore which microperimetry sensitivity index (pointwise sensitivity, mean sensitivity, and volume sensitivity) is suitable as a microperimetry outcome…”
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Correlation Between Fundus Autofluorescence Pattern and Retinal Function on Microperimetry in Choroideremia
Published in Translational vision science & technology (01-09-2023)“…In patients with choroideremia, it is not known how smooth and mottled patterns on short-wavelength fundus autofluorescence (AF) imaging relate to retinal…”
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Low Luminance Visual Acuity and Low Luminance Deficit in Choroideremia and RPGR-Associated Retinitis Pigmentosa
Published in Translational vision science & technology (18-02-2021)“…Choroideremia and RPGR-associated retinitis pigmentosa (RP) are two distinct inherited rod-cone degenerations, where good visual acuity (VA) is maintained…”
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Generalized constraints on the curvature perturbation from primordial black holes
Published in Physical review. D, Particles, fields, gravitation, and cosmology (01-05-2009)Get full text
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Changes in Retinal Sensitivity Associated With Cotoretigene Toliparvovec in X-Linked Retinitis Pigmentosa With RPGR Gene Variations
Published in JAMA ophthalmology (01-03-2023)“…X-linked retinitis pigmentosa (XLRP) is a severe cause of early-onset RP in male individuals, characterized by degeneration of photoreceptors, an extinguished…”
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Assessment of Visual Function with Cotoretigene Toliparvovec in X-Linked Retinitis Pigmentosa in the Randomized XIRIUS Phase 2/3 Study
Published in Ophthalmology (Rochester, Minn.) (01-09-2024)“…Cotoretigene toliparvovec (BIIB112/AAV8-RPGR) is an investigational vector-based gene therapy designed to provide a full-length, codon-optimized retinitis…”
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Constraints from primordial black hole formation at the end of inflation
Published in Physical review. D, Particles, fields, gravitation, and cosmology (25-08-2010)Get full text
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XOLARIS: A 24-Month, Prospective, Natural History Study of 201 Participants with Retinitis Pigmentosa GTPase Regulator-Associated X-Linked Retinitis Pigmentosa
Published in Ophthalmology science (Online) (01-01-2025)“…To improve the understanding of the natural disease progression of retinitis pigmentosa GTPaseregulator (RPGR)-associated X-linked retinitis pigmentosa (XLRP)…”
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Gamma-rays from ultracompact minihalos: potential constraints on the primordial curvature perturbation
Published 06-10-2010“…Phys.Rev.D82:083527,2010 Ultracompact minihalos (UCMHs) are dense dark matter structures which can form from large density perturbations shortly after…”
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Constraints from primordial black hole formation at the end of inflation
Published 02-08-2010“…Phys.Rev.D82:047303,2010 Primordial black hole (PBH) abundance limits constrain the primordial power spectrum, and hence models of inflation, on scales far…”
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