Search Results - "Jos P. M. Bökkerink"
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Is screening for abnormal ECG patterns justified in long‐term follow‐up of childhood cancer survivors treated with anthracyclines?
Published in Pediatric blood & cancer (01-03-2017)“…Background ECG and echocardiography are noninvasive screening tools to detect subclinical cardiotoxicity in childhood cancer survivors (CCSs). Our aims were as…”
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Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997–2004)
Published in The lancet oncology (01-10-2009)“…Summary Background A population-based cohort of children aged 1–18 years with acute lymphoblastic leukaemia (ALL) was treated with a dexamethasone-based…”
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3
Prospective Study on Incidence, Risk Factors, and Long-Term Outcome of Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia
Published in Journal of clinical oncology (01-11-2011)“…We studied cumulative incidence, risk factors, therapeutic strategies, and outcome of symptomatic osteonecrosis in pediatric patients with acute lymphoblastic…”
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Bone mineral density at diagnosis determines fracture rate in children with acute lymphoblastic leukemia treated according to the DCOG-ALL9 protocol
Published in Bone (New York, N.Y.) (01-02-2014)“…Abstract Purpose To elucidate incidence and risk factors of bone mineral density and fracture risk in children with Acute Lymphoblastic Leukemia (ALL). Methods…”
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Myocardial Strain and Strain Rate in Monitoring Subclinical Heart Failure in Asymptomatic Long-Term Survivors of Childhood Cancer
Published in Ultrasound in medicine & biology (01-11-2010)“…Abstract We studied the role of global myocardial strain and strain rate in monitoring subclinical heart failure in a large group of asymptomatic long-term…”
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Dexamethasone in the maintenance phase of acute lymphoblastic leukaemia treatment: Is the risk of lethal infections too high?
Published in European journal of cancer (1990) (01-11-2007)“…Abstract We report an increased incidence of infectious deaths during maintenance treatment of the ninth protocol for acute lymphoblastic leukaemia of the…”
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Monitoring of inosine monophosphate dehydrogenase activity in mononuclear cells of children with acute lymphoblastic leukemia: Enzymological and clinical aspects
Published in Pediatric Blood & Cancer (01-04-2006)“…Background Inosine 5′‐monophosphate dehydrogenase (IMPDH; EC1.1.1.205) catalyzes the rate‐limiting step in guanine nucleotide biosynthesis, and may play an…”
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Abnormal NT-pro-BNP levels in asymptomatic long-term survivors of childhood cancer treated with anthracyclines
Published in Pediatric blood & cancer (01-05-2009)“…Background Anthracycline‐induced cardiotoxicity can cause serious health problems for an increasing number of survivors of childhood malignancies. The aims of…”
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AGORA, a data- and biobank for birth defects and childhood cancer
Published in Birth defects research. A Clinical and molecular teratology (01-08-2016)“…BACKGROUND Research regarding the etiology of birth defects and childhood cancer is essential to develop preventive measures, but often requires large study…”
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10
Salvage Therapy of Progressive and Recurrent Hodgkin’s Disease: Results From a Multicenter Study of the Pediatric DAL/GPOH-HD Study Group
Published in Journal of clinical oncology (01-09-2005)“…To evaluate a salvage therapy (ST-HD-86) for patients with progressive and relapsed Hodgkin's disease after primary treatment in the pediatric DAL/GPOH…”
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Gemtuzumab ozogamicin: first clinical experiences in children with relapsed/refractory acute myeloid leukemia treated on compassionate-use basis
Published in Blood (15-05-2003)“…Gemtuzumab ozogamicin (GO; Mylotarg) was developed to treat CD33+ acute myeloid leukemia (AML). To date, only studies in adults and preliminary data from a…”
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Intrathecal vincristine: 3 fatal cases and a review of the literature
Published in Journal of pediatric hematology/oncology (01-11-2009)“…We report 3 cases of accidental intrathecal vincristine administration. All 3 patients died between 8 and 18 days after the incident because of decerebration…”
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Thiopurine methyltransferase in acute lymphoblastic leukaemia: biochemical and molecular biological aspects
Published in European journal of cancer (1990) (01-03-2005)“…Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme, catalysing S-methylation of aromatic and heterocyclic sulphhydryl compounds. TPMT activities and…”
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14
Amphotericin B-deoxycholate overdose due to administration error in pediatric patients
Published in Medical mycology (Oxford) (01-03-2008)“…Due to the similarity of their generic names, the use of amphotericin B-deoxycholate and liposomal amphotericin B could cause confusion in daily practice. We…”
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Real-time analysis of Tyrosine hydroxylase gene expression: A sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma
Published in Clinical cancer research (01-02-2003)“…The purpose of this study was to establish a sensitive and semiquantitative method for the detection of minimal residual disease of neuroblastoma, the most…”
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Values of high sensitive troponin T in long-term survivors of childhood cancer treated with anthracyclines
Published in Clinica chimica acta (20-02-2015)“…Cardiac biomarkers can play an important role in the early detection of subclinical heart failure. Our aims are to 1) obtain values of high sensitive cardiac…”
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Measurement of thiopurine S-methyltransferase activity in human blood samples based on high-performance liquid chromatography: reference values in erythrocytes from children
Published in Annals of clinical biochemistry (01-01-2003)“…Monitoring 6-thiopurine S-methyltransferase (TPMT; EC 2.1.1.67) activity is especially important when patients are treated with 6-thiopurine drugs, since…”
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Cryptococcal meningitis in a child with acute lymphoblastic leukemia
Published in The Pediatric infectious disease journal (01-06-2003)Get full text
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Role of 5′-nucleotidase in thiopurine metabolism: Enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine treatment
Published in Clinica chimica acta (01-11-2005)“…Thiopurines are used for treatment of several diseases. Cytotoxicity is caused by the derived compounds 6-thioguanine nucleotides (TGNs) and…”
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20
Real-Time Analysis of Tyrosine Hydroxylase Gene Expression
Published in Clinical cancer research (01-02-2003)“…Purpose: The purpose of this study was to establish a sensitive and semiquantitativemethod for the detection of minimal residual diseaseof neuroblastoma, the…”
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