Search Results - "José do Espírito Santo Junior"

A Single Haplotype of IFNG Correlating With Low Circulating Levels of Interferon-γ Is Associated With Susceptibility to Cutaneous Leishmaniasis Caused by Leishmania guyanensis by da Silva, George A V, Mesquita, Tirza G, Souza, Victor C, Junior, José do Espírito Santo, Gomes de Souza, Mara Lúcia, Talhari, Anette Chrusciak, Talhari, Sinésio, Naveca, Felipe G, Ramasawmy, Rajendranath

“…Abstract Background Interferon-γ (IFN-γ) plays an important role in the control of Leishmania infection. Blockade of IFN-γ signaling in mice increases lesion…”
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Variants of MIRNA146A rs2910164 and MIRNA499 rs3746444 are associated with the development of cutaneous leishmaniasis caused by Leishmania guyanensis and with plasma chemokine IL-8 by de Mesquita, Tirza Gabrielle Ramos, Junior, José do Espírito Santo, de Lacerda, Thais Carneiro, Queiroz, Krys Layane Guimarães Duarte, Júnior, Cláudio Marcello da Silveira, Neto, José Pereira de Moura, Gomes, Lissianne Augusta Matos, de Souza, Mara Lúcia Gomes, Guerra, Marcus Vinitius de Farias, Ramasawmy, Rajendranath

“…Leishmania are intracellular protozoan parasites that cause a wide spectrum of clinical manifestations in genetically susceptible individuals with an…”
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Caspase-1 Variants and Plasma IL-1β in Patients with Leishmania guyanensis Cutaneous Leishmaniasis in the Amazonas by de Souza, Josué Lacerda, de Farias Guerra, Marcus Vinitius, de Mesquita, Tirza Gabrielle Ramos, Junior, José do Espírito Santo, Sequera, Hector David Graterol, da Silva, Lener Santos, da Silva, Larissa Almeida, Moura, Filipe Menezes, Menescal, Lizandra Stephanny Fernandes, da Costa Torres, Júlia, Pinheiro, Suzana Kanawati, Kerr, Herllon Karllos Athaydes, Ogusku, Mauricio Morishi, de Souza, Mara Lúcia Gomes, de Moura Neto, Jose Pereira, Sadahiro, Aya, Ramasawmy, Rajendranath

“…Leishmaniasis, a disease caused by protozoan Leishmania spp., exhibits a broad range of clinical manifestations. Host resistance or susceptibility to…”
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A polymorphism in the IL1B gene (rs16944 T/C) is associated with cutaneous leishmaniasis caused by Leishmania guyanensis and plasma cytokine interleukin receptor antagonist by da Silva, George Allan Villarouco, de Mesquita, Tirza Gabrielle Ramos, de Souza Encarnação, Helia Valeria, do Espírito Santo Junior, José, da Costa Sabino, Karolina, de Aguiar Neres, Isaac, de Almeida, Salim Assad, de Souza, Mara Lúcia Gomes, Talhari, Sinésio, Ramasawmy, Rajendranath

“…•Leishmania activate the NLRP3 inflammasome in infected macrophages and enhance the secretion IL-1β.•Polymorphisms in IL1B and IL1RN genes are studied in 881…”
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Variants of CARD8 in Leishmania guyanensis-cutaneous leishmaniasis and influence of the variants genotypes on circulating plasma cytokines IL-1β, TNFα and IL-8 by Sequera, Héctor David Graterol, Souza, Josué Lacerda de, Junior, José do Espírito Santo, Silva, Lener Santos da, Pinheiro, Suzana Kanawati, Kerr, Herllon Karllos Athaydes, Souza, Mara Lúcia Gomes de, Guerra, Marcus Vinitius de Farias, Mesquita, Tirza Gabrielle Ramos de, Ramasawmy, Rajendranath

“…Nucleotide-binding oligomerization domain, leucine-rich repeat-containing protein family (NLR) are intracellular pathogen recognition receptors mediating…”
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A fine mapping of single nucleotide variants and haplotype analysis of IL13 gene in patients with Leishmania guyanensis-cutaneous leishmaniasis and plasma cytokines IL-4, IL-5, and IL-13 by Junior, José do Espírito Santo, Souza, Josué Lacerda de, Silva, Lener Santos da, Silva, Cilana Chagas da, Nascimento, Tuanny Arruda do, Souza, Mara Lúcia Gomes de, Cunha, Alyne Farias da, Batista, Jacqueline da Silva, Neto, José Pereira de Moura, Guerra, Marcus Vinitius de Farias, Ramasawmy, Rajendranath

“…IntroductionLeishmaniasis continues to pose a substantial health burden in 97 countries worldwide. The progression and outcome of Leishmania infection are…”
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Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania (V.) guyanensis in Manaus, Amazonas, Brazil by de Araújo Santos, Felipe Jules, da Silva, Lener Santos, Júnior, José do Espírito Santo, Ramos de Mesquita, Tirza Gabrielle, de Souza, Mara Lúcia Gomes, de Andrade Júnior, Moacir Couto, Talhari, Sinésio, Ramasawmy, Rajendranath

“…Leishmaniasis is a disease caused by intracellular protozoan parasites of the genus Leishmania. In endemic areas, only a portion of exposed subjects develops…”
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IL-23R Variant rs11805303 Is Associated With Susceptibility to the Development of Cutaneous Leishmaniasis in Leishmania guyanensis–Infected Individuals by Santos da Silva, Lener, Santo Júnior, José do Espírito, de Mesquita, Tirza Gabrielle Ramos, Santos, Veronica Alice Marinho, de Souza, Josué Lacerda, de Araújo, Felipe Jules, da Silveira Júnior, Cláudio Marcello, da Silva, Cilana Chagas, Queiroz, Krys Layane Guimarães Duarte, Sequera, Héctor David Graterol, Guerra, Marcus Vinitius de Farias, de Souza, Mara Lúcia Gomes, Ramasawmy, Rajendranath

“…Abstract Background Emerging evidence suggests that the interleukin (IL) 17/ IL-23 axis may play a role in the pathogenesis of leishmaniasis. Our aim was to…”
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TREM1 rs2234237 (Thr25Ser) Polymorphism in Patients with Cutaneous Leishmaniasis Caused by Leishmania guyanensis : A Case-Control Study in the State of Amazonas, Brazil by do Espírito Santo Júnior, José, Gabrielle Ramos de Mesquita, Tirza, Diego Oliveira da Silva, Luan, Jules de Araújo, Felipe, Lacerda de Souza, Josué, Carneiro de Lacerda, Thaís, Santos da Silva, Lener, Marcello da Silveira Júnior, Cláudio, Layane Guimarães Duarte Queiroz, Krys, Dos Santos, Diogo Matos, Chagas da Silva, Cilana, David Graterol Sequera, Héctor, Tamayo Hermida, Melissa, Lúcia Gomes de Souza, Mara, Vinitius de Farias Guerra, Marcus, Ramasawmy, Rajendranath

“…Leishmaniasis is an infectious disease caused by parasites. A Th1 immune response is necessary in the acute phase to control the pathogen. The triggering…”
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Variants of NOD2 in Leishmania guyanensis-infected patients with cutaneous leishmaniasis and correlations with plasma circulating pro-inflammatory cytokines by Mesquita, Tirza Gabrielle Ramos de, Junior, José do Espírito Santo, Souza, Josué Lacerda de, Silva, Lener Santos da, Nascimento, Tuanny Arruda do, Souza, Mara Lúcia Gomes de, Guerra, Marcus Vinitius de Farias, Ramasawmy, Rajendranath

“…Leishmaniases, a group of vector-borne diseases, are caused by the protozoan intracellular parasite Leishmania (L.) and are transmitted by the phlebotomine…”
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Variants of CARD8 in Leishmania guyanensis-cutaneous leishmaniasis and influence of the variants genotypes on circulating plasma cytokines IL-1[beta], TNF[alpha] and IL-8 by Sequera, Héctor David Graterol, Souza, Josué Lacerda de, Junior, José do Espírito Santo, Silva, Lener Santos da, Pinheiro, Suzana Kanawati, Kerr, Herllon Karllos Athaydes, Souza, Mara Lúcia Gomes de, Guerra, Marcus Vinitius de Farias, Mesquita, Tirza Gabrielle Ramos de, Ramasawmy, Rajendranath

“…Nucleotide-binding oligomerization domain, leucine-rich repeat-containing protein family (NLR) are intracellular pathogen recognition receptors mediating…”
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Variants of NOD2 in Leishmania guyanensis-infected patients with cutaneous leishmaniasis and correlations with plasma circulating pro-inflammatory cytokines by Tirza Gabrielle Ramos de Mesquita, José do Espírito Santo Junior, Josué Lacerda de Souza, Lener Santos da Silva, Tuanny Arruda do Nascimento, Mara Lúcia Gomes de Souza, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy

“…Leishmaniases, a group of vector-borne diseases, are caused by the protozoan intracellular parasite Leishmania (L.) and are transmitted by the phlebotomine…”
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Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania by de Araújo Santos, Felipe Jules, da Silva, Lener Santos, Júnior, José do Espírito Santo, Ramos de Mesquita, Tirza Gabrielle, de Souza, Mara Lúcia Gomes, de Andrade Júnior, Moacir Couto, Talhari, Sinésio, Ramasawmy, Rajendranath

“…Leishmaniasis is a disease caused by intracellular protozoan parasites of the genus Leishmania. In endemic areas, only a portion of exposed subjects develops…”
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Distinct plasma chemokines and cytokines signatures in Leishmania guyanensis-infected patients with cutaneous leishmaniasis by Mesquita, Tirza Gabrielle Ramos de, Junior, José do Espírito Santo, Silva, Luan Diego Oliveira da, Silva, George Allan Villarouco, Araújo, Felipe Jules de, Pinheiro, Suzana Kanawati, Kerr, Herllon Karllos Athaydes, Silva, Lener Santos da, Souza, Luciane Macedo de, Almeida, Samir Assad de, Queiroz, Krys Layane Guimarães Duarte, Souza, Josué Lacerda de, Silva, Cilana Chagas da, Sequera, Héctor David Graterol, Souza, Mara Lúcia Gomes de, Barbosa, Anderson Nogueira, Pontes, Gemilson Soares, Guerra, Marcus Vinitius de Farias, Ramasawmy, Rajendranath

“…The immunopathology associated with Leishmaniasis is a consequence of inflammation. Upon infection with Leishmania , the type of host-immune response is…”
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