Search Results - "José Oñate-Garzón"
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Characterization and Classification In Silico of Peptides with Dual Activity (Antimicrobial and Wound Healing)
Published in International journal of molecular sciences (01-09-2023)“…The growing challenge of chronic wounds and antibiotic resistance has spotlighted the potential of dual-function peptides (antimicrobial and wound healing) as…”
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Synthesis, Characterization, and Biological Evaluation of Chitosan Nanoparticles Cross-Linked with Phytic Acid and Loaded with Colistin against Extensively Drug-Resistant Bacteria
Published in Pharmaceutics (01-09-2024)“…The natural evolution of microorganisms, as well as the inappropriate use of medicines, have accelerated the problem of drug resistance to many of the…”
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Antibacterial Activity of a Cationic Antimicrobial Peptide against Multidrug-Resistant Gram-Negative Clinical Isolates and Their Potential Molecular Targets
Published in Molecules (Basel, Switzerland) (30-10-2020)“…Antimicrobial resistance reduces the efficacy of antibiotics. Infections caused by multidrug-resistant (MDR), Gram-negative bacterial strains, such as (MDRKp)…”
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Decrease of Antimicrobial Resistance through Polyelectrolyte-Coated Nanoliposomes Loaded with β-Lactam Drug
Published in Pharmaceuticals (Basel, Switzerland) (23-12-2018)“…Currently, one of the greatest health challenges worldwide is the resistance to antibiotic drugs, which has led to the pursuit of new alternatives for the…”
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Peptides with Dual Antimicrobial-Anticancer Activity: Strategies to Overcome Peptide Limitations and Rational Design of Anticancer Peptides
Published in Molecules (Basel, Switzerland) (16-09-2020)“…Peptides are naturally produced by all organisms and exhibit a wide range of physiological, immunomodulatory, and wound healing functions. Furthermore, they…”
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In Silico Discovery of Antimicrobial Peptides as an Alternative to Control SARS-CoV-2
Published in Molecules (Basel, Switzerland) (25-11-2020)“…A serious pandemic has been caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The interaction between spike surface viral protein…”
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Evaluation of the Antimicrobial Activity of Cationic Peptides Loaded in Surface-Modified Nanoliposomes against Foodborne Bacteria
Published in International journal of molecular sciences (05-02-2019)“…Bacteria are a common group of foodborne pathogens presenting public health issues with a large economic burden for the food industry. Our work focused on a…”
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In Vitro Evaluation of the Potential Pharmacological Activity and Molecular Targets of New Benzimidazole-Based Schiff Base Metal Complexes
Published in Antibiotics (Basel) (16-06-2021)“…Metal-based drugs, including lanthanide complexes, have been extremely effective in clinical treatments against various diseases and have raised major interest…”
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Development of Antioxidant-Loaded Nanoliposomes Employing Lecithins with Different Purity Grades
Published in Molecules (Basel, Switzerland) (16-11-2020)“…This work focused on comparing the ability of lecithins with two purity grades regarding their performance in the development of nanoliposomes, as well as…”
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Validation by Molecular Dynamics of the Major Components of Sugarcane Vinasse, On a Surface of Calcium Carbonate (Calcite)
Published in Molecules (Basel, Switzerland) (18-04-2021)“…There is ongoing interest in the alcohol industry to significantly reduce and/or add value to the liquid residue, vinasse, produced after the distillation and…”
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Design, Synthesis and Antimicrobial Potential of Conjugated Metallopeptides Targeting DNA
Published in Scientia pharmaceutica (01-04-2024)“…Antimicrobial resistance threatens the effective prevention and treatment of an increasingly broad spectrum of infections caused by pathogenic microorganisms…”
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A Study of the Interaction of a New Benzimidazole Schiff Base with Synthetic and Simulated Membrane Models of Bacterial and Mammalian Membranes
Published in Membranes (Basel) (16-06-2021)“…Biological membranes are complex dynamic systems composed of a great variety of carbohydrates, lipids, and proteins, which together play a pivotal role in the…”
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A Novel Cecropin D-Derived Short Cationic Antimicrobial Peptide Exhibits Antibacterial Activity Against Wild-Type and Multidrug-Resistant Strains of Klebsiella pneumoniae and Pseudomonas aeruginosa
Published in Evolutionary bioinformatics online (2020)“…Infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa and Klebsiella pneumoniae are a serious worldwide public health concern due to the…”
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Relationship between the Ionization Degree and the Inter-Polymeric Aggregation of the Poly(maleic acid- alt -octadecene) Salts Regarding Time
Published in Polymers (02-05-2020)“…Alternating amphiphilic copolymers are macromolecular systems with a polarity duality in their structure, since they are generally formed by alternating…”
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In Silico Selection and Evaluation of Pugnins with Antibacterial and Anticancer Activity Using Skin Transcriptome of Treefrog ( Boana pugnax )
Published in Pharmaceutics (18-04-2021)“…In order to combat bacterial and cancer resistance, we identified peptides (pugnins) with dual antibacterial l-anticancer activity from the ( ) skin…”
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Specific Focus on Antifungal Peptides against Azole Resistant Aspergillus fumigatus : Current Status, Challenges, and Future Perspectives
Published in Journal of fungi (Basel) (27-12-2022)“…The prevalence of fungal infections is increasing worldwide, especially that of aspergillosis, which previously only affected people with immunosuppression…”
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Antimicrobial Contribution of Chitosan Surface-Modified Nanoliposomes Combined with Colistin against Sensitive and Colistin-Resistant Clinical Pseudomonas aeruginosa
Published in Pharmaceutics (30-12-2020)“…Colistin is a re-emergent antibiotic peptide used as a last resort in clinical practice to overcome multi-drug resistant (MDR) Gram-negative bacterial…”
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Studies on the Interaction of Alyteserin 1c Peptide and Its Cationic Analogue with Model Membranes Imitating Mammalian and Bacterial Membranes
Published in Biomolecules (Basel, Switzerland) (25-09-2019)“…Antimicrobial peptides (AMPs) are effector molecules of the innate immune system and have been isolated from multiple organisms. Their antimicrobial properties…”
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Synthesis, biological evaluation and model membrane studies on metal complexes containing aromatic N,O-chelate ligands
Published in Heliyon (01-06-2020)“…Novel lanthanide (Ln) compounds [Ln(L)2]Cl.xH2O (Ln = La3+, Ce3+, Sm3+) containing aromatic N,O-chelate ligands [HL1 = 4-amino-2-(1H-benzimidazol-2-yl)phenol;…”
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Development, Characterization, and Antimicrobial Evaluation of Ampicillin-Loaded Nanoparticles Based on Poly(maleic acid- co -vinylpyrrolidone) on Resistant Staphylococcus aureus Strains
Published in Molecules (Basel, Switzerland) (05-05-2022)“…This study was focused on synthesizing, characterizing, and evaluating the antimicrobial effect of polymer nanoparticles (NPs) loaded with ampicillin. For…”
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