Search Results - "José Luis Castrejón-Flores"
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Microbiome distribution modeling using gradient descent strategies for mock, in vitro and clinical community distributions
Published in PloS one (21-08-2023)“…The human gut is home to a complex array of microorganisms interacting with the host and each other, forming a community known as the microbiome. This…”
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Advances in Our Understanding of the Interaction of Drugs with T‑cells: Implications for the Discovery of Biomarkers in Severe Cutaneous Drug Reactions
Published in Chemical research in toxicology (18-07-2022)“…Drugs can activate different cells of the immune system and initiate an immune response that can lead to life-threatening diseases collectively known as severe…”
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3
Angiotensin-I-converting enzyme inhibitory, antimicrobial, and antioxidant effect of bioactive peptides obtained from different varieties of common beans (Phaseolus vulgaris L.) with in vivo antihypertensive activity in spontaneously hypertensive rats
Published in European food research & technology (01-11-2014)“…Peptides obtained from three varieties of common beans (Phaseolus vulgaris L.) named plus black (PB), azufrado higuera (AH) and pinto Saltillo (PS) presented…”
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4
Characterizing the thermal degradation mechanism of two bisphosphoramidates by TGA, DSC, mass spectrometry and first-principle theoretical protocols
Published in Journal of molecular structure (05-12-2020)“…The present investigation describes a combined experimental-theoretical strategy to assess the thermal resistance features of two symmetric…”
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Synthesis of new aromatic phosphoramidates under a three-component reaction
Published in Phosphorus, sulfur, and silicon and the related elements (2022)“…A fast, safe and accessible multicomponent reaction procedure is reported for the synthesis of symmetric and nonsymmetric benzyl-bisphosphoramidate…”
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A new tricomponent reaction for the synthesis of symmetric and asymmetric alkyl bisphosphoramidates
Published in Phosphorus, sulfur, and silicon and the related elements (03-10-2021)“…A novel three-component one-pot reaction procedure was designed for the synthesis of symmetric and asymmetric bisphosphoramidate derivatives. Our key reactants…”
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Obtaining symmetric and asymmetric bisphosphoramidates and bisphosphoramidothioates by a single step multicomponent reaction
Published in Phosphorus, sulfur, and silicon and the related elements (13-08-2021)“…We present a new single-step multicomponent reaction strategy for the synthesis of symmetric and (novel) asymmetric bisphosphoramidate and…”
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Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity
Published in Toxicological sciences (28-02-2022)“…Abstract An emerging clinical issue associated with immune-oncology agents is the collateral effects on the tolerability of concomitant medications. One report…”
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Multicomponent one-pot synthesis of (dihydro-1H-benzo[d]imidazole) phosphonate
Published in Phosphorus, sulfur, and silicon and the related elements (02-11-2019)“…We present a multicomponent reaction strategy to synthesize a (dihydro-1H-benzo[d]imidazole)phosphonate family of compounds, using benzimidazoles, diethyl…”
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Shotgun Proteomics of Co-Cultured Leukemic and Bone Marrow Stromal Cells from Different Species as a Preliminary Approach to Detect Intercellular Protein Transfer
Published in Proteomes (05-04-2023)“…Cellular interactions within the bone marrow microenvironment modulate the properties of subsets of leukemic cells leading to the development of drug-resistant…”
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11
Microbiome distribution modeling using gradient descent strategies for mock, in vitro and clinical community distributions
Published in PloS one (01-01-2023)“…The human gut is home to a complex array of microorganisms interacting with the host and each other, forming a community known as the microbiome. This…”
Get full text
Journal Article -
12
Synthesis of new aromatic phosphoramidates under a three-component reaction
Published in Phosphorus, Sulfur, and Silicon and the Related Elements (30-09-2022)“…A fast, safe and accessible multicomponent reaction procedure is reported for the synthesis of symmetric and nonsymmetric benzyl-bisphosphoramidate…”
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Towards the development of mechanism-based biomarkers to diagnose drug hypersensitivity
Published in Toxicology research (Cambridge) (01-01-2015)“…Drug hypersensitivity reactions or drug allergy is a form of serious adverse drug reaction with an immunological aetiology to otherwise safe and effective…”
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The chemical synthesis of sulfonamide metabolites and their role in drug hypersensitivity
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Dissertation