Search Results - "José A. Leite"
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Surgical outcome following rotator cuff tear repair in a low-income population. Impact of obesity and smoking
Published in BMC musculoskeletal disorders (21-08-2021)“…Background Comorbidities and socioeconomic issues impact outcome of rotator cuff tear (RCT) repair. There are no data on RCT repair outcome from developing…”
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2
Potential Biological Properties of Lycopene in a Self-Emulsifying Drug Delivery System
Published in Molecules (Basel, Switzerland) (26-01-2023)“…In recent years, lycopene has been highlighted due to its antioxidant and anti-inflammatory properties, associated with a beneficial effect on human health…”
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3
A convenient renewable surface plasmon resonance chip for relative quantification of genetically modified soybean in food and feed
Published in PloS one (26-02-2020)“…The cultivation of genetically modified organisms (GMO) continues to expand worldwide. Still, many consumers express concerns about the use of GMO in food or…”
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4
Cavus Foot Correction Using a Full Percutaneous Procedure: A Case Series
Published in International journal of environmental research and public health (01-10-2021)“…Cavus foot is a tri-planar deformity that requires correction in several bones and soft tissue. Minimally invasive surgeries are less aggressive, faster and…”
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5
Neuroprotective effects on microglia and insights into the structure–activity relationship of an antioxidant peptide isolated from Pelophylax perezi
Published in Journal of cellular and molecular medicine (01-05-2022)“…© 2022 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd. This is…”
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Intragenic Antimicrobial Peptide Hs02 Hampers the Proliferation of Single- and Dual-Species Biofilms of P. aeruginosa and S. aureus : A Promising Agent for Mitigation of Biofilm-Associated Infections
Published in International journal of molecular sciences (23-07-2019)“…and are two major pathogens involved in a large variety of infections. Their co-occurrence in the same site of infection has been frequently reported and is…”
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Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity
Published in PloS one (11-05-2018)“…Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently affecting more than 200 million people. Among the various species of this…”
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Intragenic antimicrobial peptides (IAPs) from human proteins with potent antimicrobial and anti-inflammatory activity
Published in PloS one (06-08-2019)“…Following the treads of our previous works on the unveiling of bioactive peptides encrypted in plant proteins from diverse species, the present manuscript…”
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The Peptide Salamandrin-I Modulates Components Involved in Pyroptosis and Induces Cell Death in Human Leukemia Cell Line HL-60
Published in Pharmaceutics (01-07-2023)“…Amphibian secretions have been extensively investigated for the production of bioactive molecules. Salamandrin-I is an antioxidant peptide, isolated from the…”
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10
Analysis of Mechanoreceptors and Free Nerve Endings of the Transverse Carpal Ligament
Published in Hand (New York, N.Y.) (01-01-2023)“…Background: The treatment of carpal tunnel syndrome (CTS) by sectioning the transverse carpal ligament (TCL) is not exempt from complications. Some nerve…”
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Structure⁻Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells
Published in International journal of molecular sciences (19-06-2018)“…Schistosomiasis, caused by helminth flatworms of the genus , is an infectious disease mainly associated with poverty that affects millions of people worldwide…”
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Antiviral Action against SARS-CoV-2 of a Synthetic Peptide Based on a Novel Defensin Present in the Transcriptome of the Fire Salamander ( Salamandra salamandra )
Published in Pharmaceutics (29-01-2024)“…The potential emergence of zoonotic diseases has raised significant concerns, particularly in light of the recent pandemic, emphasizing the urgent need for…”
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13
The Antioxidant Peptide Salamandrin-I: First Bioactive Peptide Identified from Skin Secretion of Salamandra Genus (Salamandra salamandra)
Published in Biomolecules (Basel, Switzerland) (27-03-2020)“…Amphibian skin is a multifunctional organ that plays key roles in defense, breathing, and water balance. In this study, skin secretion samples of the fire…”
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14
Occurrence and evolutionary conservation analysis of α‐helical cationic amphiphilic segments in the human proteome
Published in The FEBS journal (01-02-2024)“…The existence of encrypted fragments with antimicrobial activity in human proteins has been thoroughly demonstrated in the literature. Recently, algorithms for…”
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15
First Bioprospecting Study of Skin Host-Defense Peptides in Odontophrynus americanus
Published in Journal of natural products (Washington, D.C.) (26-07-2024)“…The adaptation of amphibians to diverse environments is closely related to the characteristics of their skin. The complex glandular system of frog skin plays a…”
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Antioxidant and Neuroprotective Effects of the First Tryptophyllin Found in Snake Venom (Bothrops moojeni)
Published in Journal of natural products (Washington, D.C.) (23-12-2022)“…In this study, we report the isolation, characterization, and synthesis of the peptide BmT-2 belonging to the tryptophyllins family, isolated from the venom of…”
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Novel ocellatin peptides mitigate LPS-induced ROS formation and NF-kB activation in microglia and hippocampal neurons
Published in Scientific reports (14-02-2020)“…© The Author(s) 2020. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Mechanistic Insights into the Leishmanicidal and Bactericidal Activities of Batroxicidin, a Cathelicidin-Related Peptide from a South American Viper (Bothrops atrox)
Published in Journal of natural products (Washington, D.C.) (25-06-2021)“…Snake venoms are important sources of bioactive molecules, including those with antiparasitic activity. Cathelicidins form a class of such molecules, which are…”
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Anti-inflammatory and Antinociceptive Activity of Epiisopiloturine, an Imidazole Alkaloid Isolated from Pilocarpus microphyllus
Published in Journal of natural products (Washington, D.C.) (28-06-2013)“…The aim of this study was to investigate the antinociceptive and anti-inflammatory activities of epiisopiloturine (1), an imidazole alkaloid found in the…”
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BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects
Published in Amino acids (01-05-2022)“…Bombesin mediates several biological activities in the gastrointestinal (GI) tract and central nervous system in mammals, including smooth muscle contraction,…”
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