Search Results - "Jorski, Jamie"

Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration by Zhang, Chenghong, Su, Dian, Choo, Edna F, Liu, Lichuan, Bobba, Sudheer, Jorski, Jamie, Ho, Quynh, Wang, Jing, Kenny, Jane, Khojasteh, S Cyrus, Zhang, Donglu

“…is a small molecule therapeutic agent having potential to treat breast cancer. In plasma of the first-in-human study, metabolite accounting for 20.7% of total…”
Get full text

Evaluating the Utility of Canine Mdr1 Knockout Madin-Darby Canine Kidney I Cells in Permeability Screening and Efflux Substrate Determination by Chen, Eugene C, Broccatelli, Fabio, Plise, Emile, Chen, Buyun, Liu, Liling, Cheong, Jonathan, Zhang, Shu, Jorski, Jamie, Gaffney, Katherine, Umemoto, Kayla K, Salphati, Laurent

“…Permeability assays are commonly conducted with Madin-Darby canine kidney (MDCK) cells to predict the intestinal absorption of small-molecule drug candidates…”
Get full text