Search Results - "Joris, L"
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Overuse of diagnostic testing in healthcare: a systematic review
Published in BMJ quality & safety (01-01-2022)“…Overuse of diagnostic testing substantially contributes to healthcare expenses and potentially exposes patients to unnecessary harm. Our objective was to…”
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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma
Published in Nature communications (22-12-2021)“…Surgery for locoregionally advanced head and neck squamous cell carcinoma (HNSCC) results in 30‒50% five-year overall survival. In IMCISION (NCT03003637), a…”
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3
Low-value chronic prescription of acid reducing medication among Dutch general practitioners: impact of a patient education intervention
Published in BMC family practice (04-04-2024)“…Dyspepsia is a commonly encountered clinical condition in Dutch general practice, which is often treated through the prescription of acid-reducing medication…”
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Effect of individual and community-level bed net usage on malaria prevalence among under-fives in the Democratic Republic of Congo
Published in Malaria journal (18-01-2018)“…Understanding the contribution of community-level long-lasting, insecticidal net (LLIN) coverage to malaria control is critical to planning and assessing…”
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Pfhrp2-Deleted Plasmodium falciparum Parasites in the Democratic Republic of the Congo: A National Cross-sectional Survey
Published in The Journal of infectious diseases (01-07-2017)“…Background. Rapid diagnostic tests (RDTs) account for more than two-thirds of malaria diagnoses in Africa. Deletions of the Plasmodium falciparum hrp2 (pfhrp2)…”
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Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma
Published in The Journal of clinical investigation (01-10-2023)“…BACKGROUNDRecurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) is generally an incurable disease, with patients experiencing median…”
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Patterns of immune equilibrium and escape in indolent and progressing tumors
Published in Cancer cell (14-08-2023)“…By comparing indolent/slowly progressing with aggressive/rapidly progressing tumor types, Pandey et al. identify human evidence of immune equilibrium in…”
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The epidemiology of Plasmodium vivax among adults in the Democratic Republic of the Congo
Published in Nature communications (07-07-2021)“…Reports of P. vivax infections among Duffy-negative hosts have accumulated throughout sub-Saharan Africa. Despite this growing body of evidence, no nationally…”
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Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors
Published in Nature communications (21-03-2024)“…Immune checkpoint inhibitors (ICI) can achieve remarkable responses in urothelial cancer (UC), which may depend on tumor microenvironment (TME)…”
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Trends in low-value GP care during the COVID-19 pandemic: a retrospective cohort study
Published in BMC family practice (28-02-2024)“…Several studies showed that during the pandemic patients have refrained from visiting their general practitioner (GP). This resulted in medical care being…”
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Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo
Published in Scientific reports (22-03-2021)“…The majority of Plasmodium falciparum malaria diagnoses in Africa are made using rapid diagnostic tests (RDTs) that detect histidine-rich protein 2. Increasing…”
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Phase 2 trial of regorafenib in recurrent or metastatic adenoid cystic carcinoma
Published in Clinical cancer research (01-10-2024)“…There is a significant need for effective therapies to treat recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC). This study evaluated the…”
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13
Permutation Tests of Hierarchical Cluster Analyses of Carrion Communities and Their Potential Use in Forensic Entomology
Published in Journal of medical entomology (01-09-2016)“…Forensic entomologists can use carrion communities' ecological succession data to estimate the postmortem interval (PMI). Permutation tests of hierarchical…”
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Plasmodium vivax Infections in Duffy-Negative Individuals in the Democratic Republic of the Congo
Published in The American journal of tropical medicine and hygiene (01-01-2018)“…Although has been assumed to be absent from sub-Saharan Africa because of the protective mutation conferring the Duffy-negative phenotype, recent evidence has…”
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[18F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma
Published in European journal of nuclear medicine and molecular imaging (01-05-2022)“…Purpose To investigate the utility of [ 18 F]FDG-PET as an imaging biomarker for pathological response early upon neoadjuvant immune checkpoint blockade (ICB)…”
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Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial
Published in Nature medicine (01-12-2023)“…Salivary gland cancers (SGCs) are rare, aggressive cancers without effective treatments when metastasized. We conducted a phase 2 trial evaluating nivolumab…”
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Abundance and size of Gulf shrimp in Louisiana's coastal estuaries following the Deepwater Horizon oil spill
Published in PloS one (01-10-2014)“…The Deepwater Horizon oil spill impacted Louisiana's coastal estuaries physically, chemically, and biologically. To better understand the ecological…”
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Intravenous lidocaine infusion facilitates acute rehabilitation after laparoscopic colectomy
Published in Anesthesiology (Philadelphia) (2007)“…Intravenous infusion of lidocaine decreases postoperative pain and speeds the return of bowel function. The authors therefore tested the hypothesis that…”
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Validation of a Machine Learning Model to Predict Immunotherapy Response in Head and Neck Squamous Cell Carcinoma
Published in Cancers (29-12-2023)“…Head and neck squamous-cell carcinoma (HNSCC) is a disease with a generally poor prognosis; half of treated patients eventually develop recurrent and/or…”
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Drug use in the management of uncomplicated malaria in public health facilities in the Democratic Republic of the Congo
Published in Malaria journal (03-05-2018)“…Malaria the first causes of death from parasitic infection worldwide. Interventions to reduce the burden of malaria have produced a tremendous drop in malaria…”
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