Search Results - "Jorgensen, Trine"
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Immunological effects of vitamin D and their relations to autoimmunity
Published in Journal of autoimmunity (01-06-2019)“…Vitamin D deficiency is an established risk factor for many autoimmune diseases and the anti-inflammatory properties of vitamin D underscore its potential…”
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Androgen-Induced Immunosuppression
Published in Frontiers in immunology (17-04-2018)“…In addition to determining biological sex, sex hormones are known to influence health and disease regulation of immune cell activities and modulation of…”
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SLC6 neurotransmitter transporters: structure, function, and regulation
Published in Pharmacological reviews (01-09-2011)“…The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene family (also referred to as the neurotransmitter-sodium-symporter family…”
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Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains
Published in Nature communications (29-09-2017)“…Dopamine regulates reward, cognition, and locomotor functions. By mediating rapid reuptake of extracellular dopamine, the dopamine transporter is critical for…”
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Efficacy and safety of immune checkpoint inhibitors in a Danish real life non-small cell lung cancer population: a retrospective cohort study
Published in Acta oncologica (03-07-2019)“…To investigate effect and toxicity of immune checkpoint inhibition (ICI) in a Danish real-life non-small cell lung cancer (NSCLC) population. By including…”
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Quality of life in patients with cancer during the COVID-19 pandemic - a Danish cross-sectional study (COPICADS)
Published in Acta oncologica (02-01-2021)“…The COVID-19 pandemic is an international public health crisis. The risk of getting an infection with COVID-19 might impact the emotional well-being in…”
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Centralisation of Vascular Surgery: A Danish Perspective
Published in European journal of vascular and endovascular surgery (01-06-2023)Get full text
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Low-dose aspirin and rupture of abdominal aortic aneurysm
Published in Journal of vascular surgery (01-03-2017)“…Objective The use of low-dose aspirin (acetylsalicylic acid [ASA]) has been suggested to attenuate growth of abdominal aortic aneurysms (AAAs), yet solid…”
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Low Levels of Vitamin D Promote Memory B Cells in Lupus
Published in Nutrients (22-01-2020)“…: Vitamin D deficiency is a known risk factor for Systemic Lupus Erythematosus (SLE), yet clinical trials have not demonstrated efficacy and few studies have…”
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Partial Protection From Lupus-Like Disease by B-Cell Specific Type I Interferon Receptor Deficiency
Published in Frontiers in immunology (08-01-2021)“…Systemic lupus erythematosus (SLE) is an autoimmune disease that can present with many different permutations of symptom presentation. A large subset of SLE…”
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Lack of Association Between Sex Hormones, MDSCs, LDGs and pDCs in Males and Females With Systemic Lupus Erythematosus
Published in Frontiers in immunology (27-06-2022)“…Plasmacytoid dendritic cells (pDCs) and low-density granulocytes (LDGs) are interferon-alpha producing cells that create a pro-inflammatory response in…”
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Sex disparities in the immune response
Published in Cellular immunology (01-04-2015)Get full text
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The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines
Published in The Journal of biological chemistry (02-04-2010)“…The serotonin transporter (SERT) terminates neurotransmission by removing serotonin from the synaptic cleft. In addition, it is the site of action of…”
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Gr1+ cells suppress T-dependent antibody responses in (NZB x NZW)F1 male mice through inhibition of T follicular helper cells and germinal center formation
Published in The Journal of immunology (1950) (15-02-2014)“…Systemic lupus erythematosus is an autoimmune disease characterized by elevated production of autoreactive Abs. The disease has a much higher prevalence in…”
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Lupus-prone B6.Nba2 male and female mice display anti-DWEYS reactivity and a neuropsychiatric phenotype
Published in Brain, behavior, and immunity (01-05-2021)“…•B6.Nba2 lupus prone male and female mice develop severe anxiety and depression resembling NPSLE.•Serum soluble TWEAK levels are elevated in all B6.Nba2…”
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Development and feasibility of an exercise therapy intervention for older women with advanced epithelial ovarian cancer referred to neoadjuvant chemotherapy prior to possible interval debulking surgery
Published in Gynecologic oncology reports (01-08-2024)“…•Most older patients with advanced ovarian cancer were physical frail when starting neoadjuvant chemotherapy.•A physiotherapist supported exercise therapy…”
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Brain-derived Neurotrophic Factor (BDNF) Enhances GABA Transport by Modulating the Trafficking of GABA Transporter-1 (GAT-1) from the Plasma Membrane of Rat Cortical Astrocytes
Published in The Journal of biological chemistry (25-11-2011)“…The γ-aminobutyric acid (GABA) transporters (GATs) are located in the plasma membrane of neurons and astrocytes and are responsible for termination of…”
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A kinome wide screen identifies novel kinases involved in regulation of monoamine transporter function
Published in Neurochemistry international (01-09-2016)“…The high affinity transporters for the monoamine neurotransmitters, dopamine, norepinephrine, and serotonin, play a key role in controlling monoaminergic…”
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Reduced quality of life, more technical challenges, and less study motivation among paramedic students after one year of the COVID-19 pandemic - a survey study
Published in BMC medical education (01-03-2023)“…Despite the lack of knowledge about the SARS-CoV2 virus, the lack of personal protection gear among frontline healthcare workers, and lack of vaccines in the…”
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Editorial: New biomarkers for the diagnosis and treatment of systemic lupus erythematosus
Published in Frontiers in immunology (12-10-2022)Get full text
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