Search Results - "Jorgensen, Niklas R"

Extracellular purines and bone homeostasis by Agrawal, Ankita, Jørgensen, Niklas R.

“…Maintenance of a healthy skeleton is highly dependent on an intricate regulation of bone metabolism, as changes in the balance between bone formation and bone…”
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Hyperglycaemia, diabetes and risk of fragility fractures: observational and Mendelian randomisation studies by Emanuelsson, Frida, Afzal, Shoaib, Jørgensen, Niklas R., Nordestgaard, Børge G., Benn, Marianne

“…Aims/hypothesis Fragility fractures may be a complication of diabetes, partly caused by chronic hyperglycaemia. We hypothesised that: (1) individuals with…”
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Bone turnover markers in children and adolescents with type 1 diabetes—A systematic review by Madsen, Jens O. B., Jørgensen, Niklas R., Pociot, Flemming, Johannesen, Jesper

“…Type 1 diabetes (T1D) is associated with impaired bone health and both osteocalcin (OCN) and procollagen type 1 amino terminal propetide (P1NP) (markers of…”
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Accelerated tumor progression in mice lacking the ATP receptor P2X7 by Adinolfi, Elena, Capece, Marina, Franceschini, Alessia, Falzoni, Simonetta, Giuliani, Anna L, Rotondo, Alessandra, Sarti, Alba C, Bonora, Massimo, Syberg, Susanne, Corigliano, Domenica, Pinton, Paolo, Jorgensen, Niklas R, Abelli, Luigi, Emionite, Laura, Raffaghello, Lizzia, Pistoia, Vito, Di Virgilio, Francesco

“…The ATP receptor P2X7 (P2X7R or P2RX7) has a key role in inflammation and immunity, but its possible roles in cancer are not firmly established. In the present…”
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Liraglutide does not change bone turnover in clozapine- and olanzapine-treated schizophrenia overweight patients with prediabetes – randomized controlled trial by Maagensen, Henrik, Larsen, Julie R., Jørgensen, Niklas R., Fink-Jensen, Anders, Vilsbøll, Tina

“…•No effect of liraglutide was seen on bone turnover markers in patients with prediabetes and schizophrenia treated with olanzapine and/or…”
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Assessment of acute bone loading in humans using [18F]NaF PET/MRI by Haddock, Bryan, Fan, Audrey P., Uhlrich, Scott D., Jørgensen, Niklas R., Suetta, Charlotte, Gold, Garry Evan, Kogan, Feliks

“…Purpose The acute effect of loading on bone tissue and physiology can offer important information with regard to joint function in diseases such as…”
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Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose by Maagensen, Henrik, Junker, Anders E, Jørgensen, Niklas R, Gluud, Lise L, Knop, Filip K, Vilsbøll, Tina

“…Nonalcoholic fatty liver disease (NAFLD) is associated with type 2 diabetes (T2D) and vice versa, and both conditions are associated with an increased risk of…”
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Vascular Endothelial Growth Factor and Mesenchymal Stem Cells Revealed Similar Bone Formation to Allograft in a Sheep Model by Dreyer, Chris H., Jørgensen, Niklas R., Overgaard, Søren, Qin, Ling, Ding, Ming

“…Introduction. Mesenchymal stem cells (MSCs) and vascular endothelial growth factor (VEGF) are key factors in bone regeneration. Further stimulation should…”
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Kinetic [18F]-Fluoride of the Knee in Normal Volunteers by Haddock, Bryan, Fan, Audrey P, Jørgensen, Niklas R, Suetta, Charlotte, Gold, Garry Evan, Kogan, Feliks

“…PURPOSE[F]-sodium fluoride ([F]NaF) is a well-established bone-seeking agent that has shown promise to assess bone turnover in a variety of disorders, but its…”
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α-Hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis by Skals, Marianne, Jorgensen, Niklas R, Leipziger, Jens, Praetorius, Helle A

“…Escherichia coli is the dominant facultative bacterium in the normal intestinal flora. E. coli is, however, also responsible for the majority of serious…”
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P2Y12 Receptor Antagonist, Clopidogrel, Does Not Contribute to Risk of Osteoporotic Fractures in Stroke Patients by Jørgensen, Niklas R, Schwarz, Peter, Iversen, Helle K, Vestergaard, Peter

“…Stroke is a leading cause of mortality and morbidity. It is associated with excessive bone loss and risk of fracture in stroke patients is high. The P2Y12R…”
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Vitamin D Status and Muscle Function Among Adolescent and Young Swimmers by Geiker, Nina Rica Wium, Hansen, Mette, Jakobsen, Jette, Kristensen, Michael, Larsen, Rikke, Jørgensen, Niklas R, Hansen, Birthe S, Bügel, Susanne

“…Impaired muscle function has been coupled to vitamin D insufficiency in young women and in elderly men and women. Those living at Northern latitudes are at…”
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Paget's disease of the bone after treatment with Denosumab: A case report by Schwarz, Peter, Rasmussen, Anne Qvist, Kvist, Torben M, Andersen, Ulrik B, Jørgensen, Niklas R

“…Abstract Bone affection in Paget's disease is characterized by increased bone turnover localised at one or more sites of the skeleton. Bisphosphonates are the…”
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UTP-induced ATP release is a fine-tuned signalling pathway in osteocytes by Kringelbach, Tina M., Aslan, Derya, Novak, Ivana, Schwarz, Peter, Jørgensen, Niklas R.

“…Osteocytes reside as a cellular network throughout the mineralised matrix of bone and are considered the primary mechanosensors of this tissue. They sense…”
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Urokinase Plasminogen Activator Receptor Affects Bone Homeostasis by Regulating Osteoblast and Osteoclast Function by Furlan, Federico, Galbiati, Clara, Jorgensen, Niklas R, Jensen, Jens‐Erik B, Mrak, Emanuela, Rubinacci, Alessandro, Talotta, Francesco, Verde, Pasquale, Blasi, Francesco

“…The uPAR and its ligand uPA are expressed by both osteoblasts and osteoclasts. Their function in bone remodeling is unknown. We report that uPAR‐lacking mice…”
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Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study by Bryrup, Thomas, Thomsen, Cæcilie W., Kern, Timo, Allin, Kristine H., Brandslund, Ivan, Jørgensen, Niklas R., Vestergaard, Henrik, Hansen, Torben, Hansen, Tue H., Pedersen, Oluf, Nielsen, Trine

“…Aims/hypothesis Individuals with type 2 diabetes have an altered bacterial composition of their gut microbiota compared with non-diabetic individuals. However,…”
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Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia by Christensen, Mikkel B, Lund, Asger, Calanna, Salvatore, Jørgensen, Niklas R, Holst, Jens J, Vilsbøll, Tina, Knop, Filip K

“…The gut hormone glucose-dependent insulinotropic polypeptide (GIP) causes postprandial insulin release and inhibits bone resorption assessed by…”
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GLP-1 Receptor Agonist Treatment Increases Bone Formation and Prevents Bone Loss in Weight-Reduced Obese Women by Iepsen, Eva W, Lundgren, Julie R, Hartmann, Bolette, Pedersen, Oluf, Hansen, Torben, Jørgensen, Niklas R, Jensen, Jens-Erik B, Holst, Jens J, Madsbad, Sten, Torekov, Signe S

“…Context: Recent studies indicate that glucagon-like peptide (GLP)-1 regulates bone turnover, but the effects of GLP-1 receptor agonists (GLP-1 RAs) on bone in…”
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Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood by Bhattoa, Harjit P., Cavalier, Etienne, Eastell, Richard, Heijboer, Annemieke C., Jørgensen, Niklas R., Makris, Konstantinos, Ulmer, Candice Z., Kanis, John A., Cooper, Cyrus, Silverman, Stuart L., Vasikaran, Samuel D.

“…•IOF and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) consider that Procollagen type I N-propeptide (PINP) and C-terminal…”
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Elevated plasma levels of calcitonin gene-related peptide in individuals with rosacea: A cross-sectional case-control study by Wienholtz, Nita K F, Christensen, Casper E, Ashina, Håkan, Jørgensen, Niklas R, Egeberg, Alexander, Thyssen, Jacob P, Ashina, Messoud

“…Understanding the role of calcitonin gene-related peptide (CGRP) in the pathogenesis of rosacea might provide new therapeutic avenues for individuals with this…”
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