Search Results - "Jorgensen, Jens Otto L"

Prolonged erythropoietin treatment does not impact gene expression in human skeletal muscle by Christensen, Britt, Nellemann, Birgitte, Thorsen, Kasper, Nielsen, Morten Muhlig, Pedersen, Steen B., Ornstrup, Marie Juul, JØrgensen, Jens Otto L., Jessen, Niels

“…ABSTRACT Introduction We tested for the presence of erythropoietin receptor (Epo‐R) in human skeletal muscle and alterations in gene expression after prolonged…”
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Adrenal Insufficiency in Corticosteroids Use: Systematic Review and Meta-Analysis by Broersen, Leonie H. A, Pereira, Alberto M, Jørgensen, Jens Otto L, Dekkers, Olaf M

“…Objective: We aimed to estimate pooled percentages of patients with adrenal insufficiency after treatment with corticosteroids for various conditions in a…”
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Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease by Nielsen, Thomas Svava, Jessen, Niels, Jørgensen, Jens Otto L, Møller, Niels, Lund, Sten

“…Lipolysis is the process by which triglycerides (TGs) are hydrolyzed to free fatty acids (FFAs) and glycerol. In adipocytes, this is achieved by sequential…”
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High-Dose Resveratrol Supplementation in Obese Men: An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition by POULSEN, Morten M, VESTERGAARD, Poul F, CLASEN, Berthil F, RADKO, Yulia, CHRISTENSEN, Lars P, STØDKILDE-JØRGENSEN, Hans, MØLLER, Niels, JESSEN, Niels, PEDERSEN, Steen B, JØRGENSEN, Jens Otto L

“…Obesity, diabetes, hypertension, and hyperlipidemia constitute risk factors for morbidity and premature mortality. Based on animal and in vitro studies,…”
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Acromegaly incidence, prevalence, complications and long-term prognosis: a nationwide cohort study by Dal, Jakob, Feldt-Rasmussen, Ulla, Andersen, Marianne, Kristensen, Lars Ø, Laurberg, Peter, Pedersen, Lars, Dekkers, Olaf M, Sørensen, Henrik Toft, Jørgensen, Jens Otto L

“…Design Valid data on acromegaly incidence, complications and mortality are scarce. The Danish Health Care System enables nationwide studies with complete…”
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Benign Thyroid Diseases and Risk of Thyroid Cancer: A Nationwide Cohort Study by Kitahara, Cari M, Kӧrmendiné Farkas, Dóra, Jørgensen, Jens Otto L, Cronin-Fenton, Deirdre, Sørensen, Henrik Toft

“…Abstract Context Thyroid nodules, adenomas, and goiter have consistently been associated with thyroid cancer risk. Few studies have assessed whether thyroid…”
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Hyponatremia and mortality risk: a Danish cohort study of 279 508 acutely hospitalized patients by Holland-Bill, Louise, Christiansen, Christian Fynbo, Heide-Jørgensen, Uffe, Ulrichsen, Sinna Pilgaard, Ring, Troels, Jørgensen, Jens Otto L, Sørensen, Henrik Toft

“…ObjectiveWe aimed to investigate the impact of hyponatremia severity on mortality risk and assess any evidence of a dose–response relation, utilizing…”
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Corticotroph Aggressive Pituitary Tumors and Carcinomas Frequently Harbor ATRX Mutations by Casar-Borota, Olivera, Boldt, Henning Bünsow, Engström, Britt Edén, Andersen, Marianne Skovsager, Baussart, Bertrand, Bengtsson, Daniel, Berinder, Katarina, Ekman, Bertil, Feldt-Rasmussen, Ulla, Höybye, Charlotte, Jørgensen, Jens Otto L, Kolnes, Anders Jensen, Korbonits, Márta, Rasmussen, Åse Krogh, Lindsay, John R, Loughrey, Paul Benjamin, Maiter, Dominique, Manojlovic-Gacic, Emilija, Pahnke, Jens, Poliani, Pietro Luigi, Popovic, Vera, Ragnarsson, Oskar, Schalin-Jäntti, Camilla, Scheie, David, Tóth, Miklós, Villa, Chiara, Wirenfeldt, Martin, Kunicki, Jacek, Burman, Pia

“…Abstract Context Aggressive pituitary tumors (APTs) are characterized by unusually rapid growth and lack of response to standard treatment. About 1% to 2%…”
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Insulin Resistance in Patients With Acromegaly by Vila, Greisa, Jørgensen, Jens Otto L, Luger, Anton, Stalla, Günter K

“…Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes…”
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Disease Control and Gender Predict the Socioeconomic Effects of Acromegaly: A Nationwide Cohort Study by Dal, Jakob, Nielsen, Eigil H, Rasmussen, Ulla-Feldt, Andersen, Marianne, Feltoft, Claus L, Vestergaard, Peter, Stochholm, Kirstine, Jørgensen, Jens Otto L

“…Acromegaly is an insidious disease associated with severe somatic morbidity but data on socioeconomic status are scarce. To study the socioeconomic status in…”
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Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation by Bidlingmaier, Martin, Biller, Beverly M K, Clemmons, David, Jørgensen, Jens Otto L, Nishioka, Hiroshi, Takahashi, Yutaka

“…Adult growth hormone deficiency (AGHD) is a rare endocrine disorder characterized by an abnormal body composition, metabolic abnormalities associated with…”
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Serum proteome changes in acromegalic patients following transsphenoidal surgery: novel biomarkers of disease activity by Cruz-Topete, Diana, Christensen, Britt, Sackmann-Sala, Lucila, Okada, Shigeru, Jorgensen, Jens Otto L, Kopchick, John J

“…ContextTranssphenoidal adenomectomy is the primary treatment for acromegaly. However, assessment of the therapeutical outcome remains problematic since the…”
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Temporal patterns of lipolytic regulators in adipose tissue after acute growth hormone exposure in human subjects: A randomized controlled crossover trial by Hjelholt, Astrid Johannesson, Lee, Kevin Y., Arlien-Søborg, Mai Christiansen, Pedersen, Steen Bønløkke, Kopchick, John J., Puri, Vishwajeet, Jessen, Niels, Jørgensen, Jens Otto L.

“…Growth hormone (GH) stimulates lipolysis, but the underlying mechanisms remain incompletely understood. We examined the effect of GH on the expression of…”
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Growth hormone replacement in adults: Real-world data from two large studies in US and Europe by Weber, Matthias M., Gordon, Murray B., Höybye, Charlotte, Jørgensen, Jens Otto L., Puras, Gediminas, Popovic-Brkic, Vera, Molitch, Mark E., Ostrow, Vlady, Holot, Natalia, Pietropoli, Alberto, Biller, Beverly M.K.

“…Objective: This report describes the effectiveness and safety of growth hormone replacement in 3180 adult patients with growth hormone deficiency followed-up…”
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Low positive predictive value of midnight salivary cortisol measurement to detect hypercortisolism in type 2 diabetes by Steffensen, Charlotte, Thomsen, Henrik H., Dekkers, Olaf M., Christiansen, Jens S., Rungby, Jørgen, Jørgensen, Jens Otto L.

“…Summary Background Hypercortisolism is prevalent in type 2 diabetes (T2D), but analytical and functional uncertainties prevail. Measurement of salivary…”
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Prenatal exposure to glucocorticoids and the prevalence of overweight or obesity in childhood by Laugesen, Kristina, Sørensen, Henrik Toft, Jorgensen, Jens Otto L, Petersen, Irene

“…Objective Prenatal exposure to excess cortisol can affect postnatal metabolic health by epigenetic mechanisms. We aimed to investigate if prenatal exposure to…”
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Inflammatory adipokines contribute to insulin resistance in active acromegaly and respond differently to different treatment modalities by Olarescu, Nicoleta C, Ueland, Thor, Godang, Kristin, Lindberg-Larsen, Rune, Jørgensen, Jens Otto L, Bollerslev, Jens

“…BackgroundActive acromegaly is associated with insulin resistance, but it is uncertain whether inflammation in adipose tissue is a contributing factor.AimTo…”
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Use of glucocorticoids and risk of venous thromboembolism: a nationwide population-based case-control study by Johannesdottir, Sigrun A, Horváth-Puhó, Erzsébet, Dekkers, Olaf M, Cannegieter, Suzanne C, Jørgensen, Jens Otto L, Ehrenstein, Vera, Vandenbroucke, Jan P, Pedersen, Lars, Sørensen, Henrik Toft

“…Excess endogenous cortisol has been linked to venous thromboembolism (VTE) risk, but whether this relationship applies to exogenous glucocorticoids remains…”
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Circulating levels of pegvisomant and endogenous growth hormone during prolonged pegvisomant therapy in patients with acromegaly by Madsen, Michael, Fisker, Sanne, Feldt-Rasmussen, Ulla, Andreassen, Mikkel, Kristensen, Lars Østergaard, Ørskov, Hans, Jørgensen, Jens Otto L.

“…Summary Objective To investigate whether pegvisomant treatment in acromegaly induces gradual elevations in endogenous serum growth hormone (GH) levels and…”
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Multisystem Morbidity and Mortality in Cushing's Syndrome: A Cohort Study by Dekkers, Olaf M, Horváth-Puhó, Erzsébet, Jørgensen, Jens Otto L, Cannegieter, Suzanne C, Ehrenstein, Vera, Vandenbroucke, Jan P, Pereira, Alberto M, Sørensen, Henrik Toft

“…Context: Cushing's syndrome (CS) is associated with hypercoagulability, insulin resistance, hypertension, bone loss, and immunosuppression. To date, no…”
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