Search Results - "Jorge, S"

Pathogenesis of Triple-Negative Breast Cancer by Derakhshan, Fatemeh, Reis-Filho, Jorge S

“…Triple-negative breast cancer (TNBC) encompasses a heterogeneous group of fundamentally different diseases with different histologic, genomic, and immunologic…”
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Breast Cancer 2: Gene expression profiling in breast cancer: classification, prognostication, and prediction by Reis-Filho, Jorge S, Pusztai, Lajos

“…Microarray-based gene expression profiling has had a major effect on our understanding of breast cancer. Breast cancer is now perceived as a heterogeneous…”
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Genetic Interactions in Cancer Progression and Treatment by Ashworth, Alan, Lord, Christopher J., Reis-Filho, Jorge S.

“…As cancer cell genomes are unveiled at a breathtaking pace, the genetic principles at play in cancer are emerging in all their complexity, prompting the…”
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Gene expression profiling in breast cancer: classification, prognostication, and prediction by Reis-Filho, Jorge S, Prof, Pusztai, Lajos, Prof

“…Summary Microarray-based gene expression profiling has had a major effect on our understanding of breast cancer. Breast cancer is now perceived as a…”
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Migrant birds and mammals live faster than residents by Soriano-Redondo, Andrea, Gutiérrez, Jorge S., Hodgson, Dave, Bearhop, Stuart

“…Billions of vertebrates migrate to and from their breeding grounds annually, exhibiting astonishing feats of endurance. Many such movements are energetically…”
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Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance by Burns, Jorge S, Manda, Gina

“…Focus on the Warburg effect, initially descriptive of increased glycolysis in cancer cells, has served to illuminate mitochondrial function in many other…”
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Earliest Evidence of Preclinical Diabetic Retinopathy Revealed Using Optical Coherence Tomography Angiography Perfused Capillary Density by Rosen, Richard B., Andrade Romo, Jorge S., Krawitz, Brian D., Mo, Shelley, Fawzi, Amani A., Linderman, Rachel E., Carroll, Joseph, Pinhas, Alexander, Chui, Toco Y.P.

“…To compare perfused capillary density (PCD) in diabetic patients and healthy controls using optical coherence tomography angiography (OCTA). Forty controls, 36…”
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A Survey of Feature Extraction in Dermoscopy Image Analysis of Skin Cancer by Barata, Catarina, Celebi, M. Emre, Marques, Jorge S.

“…Dermoscopy image analysis (DIA) is a growing field, with works being published every week. This makes it difficult not only to keep track of all the…”
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Genetic heterogeneity and cancer drug resistance by Turner, Nicholas C, PhD, Reis-Filho, Jorge S, Prof

“…Summary Despite the success of targeted therapies in the treatment of cancer, the development of resistance limits the ability to translate this method into a…”
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Molecular dynamics and experimental study on the adhesion mechanism of polyvinyl alcohol (PVA) fiber in alkali-activated slag/fly ash by Zhang, Shizhe, Duque-Redondo, Eduardo, Kostiuchenko, Albina, Dolado, Jorge S., Ye, Guang

“…This paper aims to study the adhesion mechanism of polyvinyl alcohol (PVA) fiber within alkali-activated slag/fly ash (AASF) matrix using molecular dynamics…”
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Tunable Energy Landscapes to Control Pathway Complexity in Self‐Assembled N‐Heterotriangulenes: Living and Seeded Supramolecular Polymerization by Valera, Jorge S., Gómez, Rafael, Sánchez, Luis

“…Herein, the synthesis and self‐assembling features of N‐heterotriangulenes 1–3 decorated in their periphery with 3,4,5‐trialkoxy‐N‐(alkoxy)benzamide moieties…”
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Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor by Barber, Louise J, Sandhu, Shahneen, Chen, Lina, Campbell, James, Kozarewa, Iwanka, Fenwick, Kerry, Assiotis, Ioannis, Rodrigues, Daniel Nava, Reis-Filho, Jorge S, Moreno, Victor, Mateo, Joaquin, Molife, L Rhoda, De Bono, Johann, Kaye, Stan, Lord, Christopher J, Ashworth, Alan

“…PARP inhibitors (PARPi) for the treatment of BRCA1 or BRCA2 deficient tumours are currently the focus of seminal clinical trials exploiting the concept of…”
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Triple-Negative Breast Cancer by Foulkes, William D, Smith, Ian E, Reis-Filho, Jorge S

“…Triple-negative breast cancer, so called because it lacks expression of the estrogen receptor, progesterone receptor, and HER2, is often, but not always, a…”
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contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade by Weigelt, Britta, Baehner, Frederick L, Reis-Filho, Jorge S

“…In the last decade, the development of microarrays and the ability to perform massively parallel gene expression analysis of human tumours were received with…”
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Independent real‐world application of a clinical‐grade automated prostate cancer detection system by Silva, Leonard M, Pereira, Emilio M, Salles, Paulo GO, Godrich, Ran, Ceballos, Rodrigo, Kunz, Jeremy D, Casson, Adam, Viret, Julian, Chandarlapaty, Sarat, Ferreira, Carlos Gil, Ferrari, Bruno, Rothrock, Brandon, Raciti, Patricia, Reuter, Victor, Dogdas, Belma, DeMuth, George, Sue, Jillian, Kanan, Christopher, Grady, Leo, Fuchs, Thomas J, Reis‐Filho, Jorge S

“…Artificial intelligence (AI)‐based systems applied to histopathology whole‐slide images have the potential to improve patient care through mitigation of…”
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Histological and molecular types of breast cancer: is there a unifying taxonomy? by Reis-Filho, Jorge S, Weigelt, Britta

“…Microarray studies have been used to unravel the molecular characteristics of breast cancer and a molecular taxonomy has been proposed. The authors of this…”
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Hierarchy of Asymmetry in Chiral Supramolecular Polymers: Toward Functional, Helical Supramolecular Structures by Dorca, Yeray, Greciano, Elisa E., Valera, Jorge S., Gómez, Rafael, Sánchez, Luis

“…The formation of helical structures through the supramolecular polymerization of a variety of self‐assembling units is reviewed. These scaffolds are usually…”
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Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway by Li, Zhiqiang, Razavi, Pedram, Li, Qing, Toy, Weiyi, Liu, Bo, Ping, Christina, Hsieh, Wilson, Sanchez-Vega, Francisco, Brown, David N., Da Cruz Paula, Arnaud F., Morris, Luc, Selenica, Pier, Eichenberger, Emily, Shen, Ronglai, Schultz, Nikolaus, Rosen, Neal, Scaltriti, Maurizio, Brogi, Edi, Baselga, Jose, Reis-Filho, Jorge S., Chandarlapaty, Sarat

“…Cyclin dependent kinase 4/6 (CDK4/6) inhibitors (CDK4/6i) are effective in breast cancer; however, drug resistance is frequently encountered and poorly…”
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Micro‐ and macroparasite species richness in birds: The role of host life history and ecology by Gutiérrez, Jorge S., Piersma, Theunis, Thieltges, David W., Hoye, Bethany

“…Identifying the factors shaping variation in parasite diversity among host species is crucial to understand wildlife diseases. Although micro‐ and…”
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Shifting the paradigm in personalized cancer care through next‐generation therapeutics and computational pathology by Reis‐Filho, Jorge S., Scaltriti, Maurizio, Kapil, Ansh, Sade, Hadassah, Galbraith, Susan

“…The incorporation of novel therapeutic agents such as antibody‐drug conjugates, radio‐conjugates, T‐cell engagers, and chimeric antigen receptor cell therapies…”
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