Search Results - "Jorge, Roberta J.B."
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Effects of Tityus stigmurus (Thorell 1876) (Scorpiones: Buthidae) venom in isolated perfused rat kidneys
Published in Anais da Academia Brasileira de Ciências (01-01-2016)“…Scorpions belonging to the Tityus genus are of medical interest in Brazil. Among them, Tityus stigmurus is the main scorpion responsible for stings in the…”
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Toxicological insights of Spike fragments SARS-CoV-2 by exposure environment: A threat to aquatic health?
Published in Journal of hazardous materials (05-10-2021)“…The Spike protein (S protein) is a critical component in the infection of the new coronavirus (SARS-CoV-2). The objective of this work was to evaluate whether…”
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Three snake venoms from Bothrops genus induced apoptosis and cell cycle arrest in K562 human leukemic cell line
Published in Toxicon (Oxford) (01-02-2024)“…Cancer is indisputably one of the leading causes of death worldwide. Snake venoms are a potential source of bioactive compounds, complex mixtures constituted…”
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Tityus stigmurus venom causes genetic damage in blood and testicular cells and affects the number and morphology of gametogenic lineage cells in mice
Published in Toxicon (Oxford) (15-10-2020)“…Scorpion envenomation represents an important health problem in many parts of the world, due to the high number and severity of accidents. Recent studies…”
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L-Aminoacid Oxidase from Bothrops leucurus Venom Induces Nephrotoxicity via Apoptosis and Necrosis
Published in PloS one (20-07-2015)“…Acute renal failure is a common complication caused by Bothrops viper envenomation. In this study, the nefrotoxicity of a main component of B. leucurus venom…”
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Antinociceptive and Anti-Inflammatory Activities of Sulphated Polysaccharides from the Red Seaweed Gracilaria cornea
Published in Basic & clinical pharmacology & toxicology (01-04-2012)“…: Seaweeds have attracted special interest as good sources of sulphated polysaccharides (SP) for use in pharmaceutical industries and biotechnology. In this…”
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Protective Effects Of A Lipid Transfer Protein Isolated from Morinda citrifolia Seeds in Gentamicin-Induced Nephrotoxicity in Rats
Published in Revista brasileira de farmacognosia (01-08-2020)“…Gentamicin is an aminoglycoside antibiotic used in the treatment of gram-negative bacterial infections. However, its prolonged use is limited due to a high…”
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Antinociceptive and anti-inflammatory activities of a sulfated polysaccharide isolated from the green seaweed Caulerpa cupressoides
Published in Pharmacological reports (2012)“…Red and brown algae sulfated polysaccharides (SPs) have been widely investigated as antinociceptive and/or anti-inflammatory agents; however, no description of…”
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Bothropoides pauloensis venom effects on isolated perfused kidney and cultured renal tubular epithelial cells
Published in Toxicon (Oxford) (15-12-2015)“…Snake envenomation (Bothrops genus) is common in tropical countries and acute kidney injury is one of the complications observed in Bothrops snakebite with…”
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Peripheral antinociception and anti-edematogenic effect of a sulfated polysaccharide from Acanthophora muscoides
Published in Pharmacological reports (2013)“…Sulfated polysaccharides from red marine algae have presented a variety of potentially therapeutic biological effects, however, their antinocicpetive and…”
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Inhibitory effects of sertraline in rat isolated perfused kidneys and in isolated ring preparations of rat arteries
Published in Journal of pharmacy and pharmacology (01-09-2011)“…Objectives Sertraline is often prescribed to patients suffering with end stage renal disease, but its action on kidney has not been investigated. We aimed to…”
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In vitro studies on Bothrops venoms cytotoxic effect on tumor cells
Published in Journal of experimental therapeutics & oncology (2011)“…Animal venoms are complex mixtures of proteins and non proteins components with several biological activities. Snake venoms represent an essentially unexplored…”
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