Search Results - "Jordan, Veronica Clavijo"

Yttrium‐86 Is a Positron Emitting Surrogate of Gadolinium for Noninvasive Quantification of Whole‐Body Distribution of Gadolinium‐Based Contrast Agents by Le Fur, Mariane, Rotile, Nicholas J., Correcher, Carlos, Clavijo Jordan, Veronica, Ross, Alana W., Catana, Ciprian, Caravan, Peter

“…Gadolinium‐based contrast agents (GBCAs) are used to provide diagnostic information in clinical magnetic resonance (MR) examinations. Gadolinium (Gd) has been…”
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RNAi-Mediated PD-L1 Inhibition for Pancreatic Cancer Immunotherapy by Yoo, Byunghee, Jordan, Veronica Clavijo, Sheedy, Patrick, Billig, Ann-Marie, Ross, Alana, Pantazopoulos, Pamela, Medarova, Zdravka

“…The recent past has seen impressive progress in the treatment of various malignancies using immunotherapy. One of the most promising approaches involves immune…”
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Imaging Extracellular Lactate In Vitro and In Vivo Using CEST MRI and a Paramagnetic Shift Reagent by Zhang, Lei, Martins, André F., Mai, Yuyan, Zhao, Piyu, Funk, Alexander M., Clavijo Jordan, M. Veronica, Zhang, Shanrong, Chen, Wei, Wu, Yunkou, Sherry, A. Dean

“…Overproduction of lactate is a hallmark of cancer, yet a method to quantitatively measure lactate production by cancer cells is not straight‐forward. Chemical…”
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Simplified synthesis and relaxometry of magnetoferritin for magnetic resonance imaging by Clavijo Jordan, Veronica, Caplan, Michael R., Bennett, Kevin M.

“…Magnetoferritin nanoparticles have been developed as high‐relaxivity, functional contrast agents for MRI. Several previous techniques have relied on unloading…”
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Principles and emerging applications of nanomagnetic materials in medicine by Clavijo-Jordan, Veronica, Kodibagkar, Vikram D., Beeman, Scott C., Hann, Bradley D., Bennett, Kevin M.

“…The development of nanometer‐scale magnetic materials for biomedical applications spans the interface between the physical sciences and biology. Applications…”
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Zinc-sensitive MRI contrast agent detects differential release of Zn(II) ions from the healthy vs. malignant mouse prostate by Jordan, M. Veronica Clavijo, Lo, Su-Tang, Chen, Shiuhwei, Preihs, Christian, Chirayil, Sara, Zhang, Shanrong, Kapur, Payal, Li, Wen-Hong, DeLeon-Rodriguez, Luis M., Lubag, Angelo J. M., Rofsky, Neil M., Sherry, A. Dean

“…Many secretory tissues release Zn(II) ions along with other molecules in response to external stimuli. Here we demonstrate that secretion of Zn(II) ions from…”
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Imaging Insulin Secretion from Mouse Pancreas by MRI Is Improved by Use of a Zinc-Responsive MRI Sensor with Lower Affinity for Zn2+ Ions by Martins, André F, Clavijo Jordan, Veronica, Bochner, Filip, Chirayil, Sara, Paranawithana, Namini, Zhang, Shanrong, Lo, Su-Tang, Wen, Xiaodong, Zhao, Piyu, Neeman, Michal, Sherry, A. Dean

“…It has been demonstrated that divalent zinc ions packaged with insulin in β-cell granules can be detected by MRI during glucose-stimulated insulin secretion…”
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A Responsive Magnetic Resonance Imaging Contrast Agent for Detection of Excess Copper(II) in the Liver In Vivo by Paranawithana, Namini N, Martins, Andre F, Clavijo Jordan, Veronica, Zhao, Piyu, Chirayil, Sara, Meloni, Gabriele, Sherry, A. Dean

“…The design, synthesis, and properties of a new gadolinium-based copper-responsive magnetic resonance imaging (MRI) contrast agent is presented. The sensor…”
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The Roles of ZnT1 and ZnT4 in Glucose-Stimulated Zinc Secretion in Prostate Epithelial Cells by Lo, Su-Tang, Parrott, Daniel, Jordan, M. Veronica Clavijo, Joseph, Diya Binoy, Strand, Douglas, Lo, U-Ging, Lin, Ho, Darehshouri, Anza, Sherry, A. Dean

“…Purpose We have previously demonstrated by MRI that high glucose stimulates efflux of zinc ions from the prostate. To our knowledge, this phenomena had not…”
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Oxidative Conversion of a Europium(II)‐Based T 1 Agent into a Europium(III)‐Based paraCEST Agent that can be Detected In Vivo by Magnetic Resonance Imaging by Funk, Alexander M., Clavijo Jordan, Veronica, Sherry, A. Dean, Ratnakar, S. James, Kovacs, Zoltan

“…The Eu II complex of 1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid (DOTA) tetra(glycinate) has a higher reduction potential than most Eu II chelates…”
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Magnetic Resonance Imaging Detection of Glucose-Stimulated Zinc Secretion in the Enlarged Dog Prostate as a Potential Method for Differentiating Prostate Cancer From Benign Prostatic Hyperplasia by Khalighinejad, Pooyan, Parrott, Daniel, Jordan, Veronica Clavijo, Chirayil, Sara, Preihs, Christian, Rofsky, Neil M., Xi, Yin, Sherry, A. Dean

“…In the United States, prostate cancer (PCa) is the most common cancer in men. Multi-parametric magnetic resonance imaging (MRI) is increasingly being relied…”
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Advanced MRI of Liver Fibrosis and Treatment Response in a Rat Model of Nonalcoholic Steatohepatitis by Zhou, Iris Y, Clavijo Jordan, Veronica, Rotile, Nicholas J, Akam, Eman, Krishnan, Smitha, Arora, Gunisha, Krishnan, Hema, Slattery, Hannah, Warner, Noah, Mercaldo, Nathaniel, Farrar, Christian T, Wellen, Jeremy, Martinez, Robert, Schlerman, Franklin, Tanabe, Kenneth K, Fuchs, Bryan C, Caravan, Peter

“…Background Liver biopsy is the reference standard to diagnose nonalcoholic steatohepatitis (NASH) but is invasive with potential complications. Purpose To…”
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Amplifying the Sensitivity of Zinc(II) Responsive MRI Contrast Agents by Altering Water Exchange Rates by Yu, Jing, Martins, André F, Preihs, Christian, Clavijo Jordan, Veronica, Chirayil, Sara, Zhao, Piyu, Wu, Yunkou, Nasr, Khaled, Kiefer, Garry E, Sherry, A. Dean

“…Given the known water exchange rate limitations of a previously reported Zn­(II)-sensitive MRI contrast agent, GdDOTA-diBPEN, new structural targets were…”
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Synchrotron Radiation X‑ray Fluorescence Elemental Mapping in Healthy versus Malignant Prostate Tissues Provides New Insights into the Glucose-Stimulated Zinc Trafficking in the Prostate As Discovered by MRI by Clavijo Jordan, Veronica, Al-Ebraheem, Alia, Geraki, Kalotina, Dao, Erica, Martins, Andre F, Chirayil, Sara, Farquharson, Michael, Sherry, A. Dean

“…Prostatic zinc content is a known biomarker for discriminating normal healthy tissue from benign prostatic hyperplasia (BPH) and prostate cancer (PCa). Given…”
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Investigations into the Signaling Pathways Involving Glucose-Stimulated Zinc Secretion (GSZS) from Prostate Epithelial Cells In Vitro and In Vivo by Parrott, Daniel, Suh, Eul Hyun, Khalighinejad, Pooyan, Jordan, Veronica Clavijo, Arreola, Ivan, Lo, Su-Tang, Sherry, A. Dean

“…Purpose Recently, we reported that exposure of prostate cells in vitro or the in vivo prostate to high glucose results in release of Zn 2+ ions, a process now…”
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Oxidative Conversion of a Europium(II)-Based T1 Agent into a Europium(III)-Based paraCEST Agent that can be Detected In Vivo by Magnetic Resonance Imaging by Funk, Alexander M., Clavijo Jordan, Veronica, Sherry, A. Dean, Ratnakar, S. James, Kovacs, Zoltan

“…The EuII complex of 1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid (DOTA) tetra(glycinate) has a higher reduction potential than most EuII chelates…”
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Disruptive chemical doping in a ferritin-based iron oxide nanoparticle to decrease r2 and enhance detection with T1-weighted MRI by Clavijo Jordan, M Veronica, Beeman, Scott C, Baldelomar, Edwin J, Bennett, Kevin M

“…Inorganic doping was used to create flexible, paramagnetic nanoparticle contrast agents for in vivo molecular magnetic resonance imaging (MRI) with low…”
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Impact of dietary zinc on stimulated zinc secretion MRI in the healthy and malignant mouse prostate by Clavijo Jordan, Veronica, Martins, André F., Dao, Erica, Geraki, Kalotina, Chirayil, Sara, Wen, Xiaodong, Khalighinejad, Pooyan, Parrott, Daniel, Wang, Xiaojing, Gonzalez Pagan, Patricia, Rofsky, Neil, Farquharson, Michael, Sherry, A. Dean

“…Previous studies have shown that the zinc-responsive MRI probe, GdL1, can distinguish healthy versus malignant prostate tissues based upon differences in zinc…”
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Development and Use of Human Recombinant 64Cu-rHCF as a Kidney Glomerulus-Targeted Contrast Agent for Positron Emission Tomography by Baldelomar, Edwin J., Zhang, Hanwen, Thorek, Daniel, Charlton, Jennifer R., Walker, Patrick D., Wilson, Leslie D., Emoto, Kasey C., Clavijo Jordan, Veronica, Reichert, David E., Shoghi, Kooresh, Bennett, Kevin M.

“…In this work, we develop recombinant human cationic ferritin (rHCF) as a contrast agent to detect glomeruli in the kidney using positron emission tomography…”
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Imaging Beta-Cell Function in the Pancreas of Non-Human Primates Using a Zinc-Sensitive MRI Contrast Agent by Clavijo Jordan, Veronica, Hines, Catherine D G, Gantert, Liza T, Wang, Shubing, Conarello, Stacey, Preihs, Christian, Chirayil, Sara, Klimas, Michael, Evelhoch, Jeffrey L, Sherry, A Dean

“…Non-invasive beta cell function measurements may provide valuable information for improving diabetes diagnostics and disease management as the integrity and…”
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