Search Results - "Jordan, Holly L."

Effects of Kupffer Cell Depletion on Acute Alpha-Naphthylisothiocyanate-induced Liver Toxicity in Male Mice by Cullen, John M., Faiola, Brenda, Melich, David H., Peterson, Richard A., Jordan, Holly L., Kimbrough, Carie L., Prescott, Judith S., Miller, Richard T.

“…Depletion of Kupffer cells, known to modulate chemical-induced hepatocellular injury, has not been studied with regard to biliary epithelial injury. Here, the…”
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Toxicity and toxicokinetics of metformin in rats by Quaile, Michael P., Melich, David H., Jordan, Holly L., Nold, James B., Chism, Jack P., Polli, Joseph W., Smith, Glenn A., Rhodes, Melissa C.

“…Metformin is a first-line drug for the treatment of type 2 diabetes (T2D) and is often prescribed in combination with other drugs to control a patient's blood…”
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Acute Alpha-Naphthylisothiocyanate-induced Liver Toxicity in Germfree and Conventional Male Rats by Cullen, John M., Faiola, Brenda, Melich, David H., Peterson, Richard A., Jordan, Holly L., Kimbrough, Carie L., Miller, Richard T.

“…Differences in the responses of conventional and germfree male Sprague-Dawley rats to acute injury induced by alpha-naphthylisothiocyanate (ANIT), a…”
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Nontraditional Applications in Clinical Pathology by Jordan, Holly L., Register, Thomas C., Tripathi, Niraj K., Bolliger, Anne Provencher, Everds, Nancy, Zelmanovic, David, Poitout, Florence, Bounous, Denise I., Wescott, Debra, Ramaiah, Shashi K.

“…Most published reviews of preclinical toxicological clinical pathology focus on the fundamental aspects of hematology, clinical chemistry, coagulation, and…”
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Biliary Proliferative Lesions in the Sprague-Dawley Rat: Adverse/Non-adverse by Hailey, James R., Nold, James B., Brown, Roger H., Cullen, John M., Holder, Julie C., Jordan, Holly L., Ennulat, Daniela, Miller, Richard T.

“…Whether biliary proliferative lesions in nonclinical species are predictive of potential hepatotoxicity in humans depends, at least in part, on the nature and…”
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Mucosally Transmitted Feline Immunodeficiency Virus Induces a CD8+ Antiviral Response that Correlates with Reduction of Cell-Associated Virus by Bucci, Joseph G., English, Robert V., Jordan, Holly L., Childers, Tedd A., Tompkins, Mary B., Tompkins, Wayne A. F.

“…Intravaginal inoculation of cats with feline immunodeficiency virus (FIV) results in acute systemic infection accompanied by a strong CD8+ immune response that…”
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An initial characterization of N-terminal-proatrial natriuretic peptide in serum of Sprague Dawley rats by Colton, Heidi M, Stokes, Alan H, Yoon, Lawrence W, Quaile, Michael P, Novak, Paul J, Falls, James Greg, Kimbrough, Carie L, Cariello, Neal F, Jordan, Holly L, Berridge, Brian R

“…In the clinical setting, natriuretic peptides (NPs) have proven to be reliable noninvasive markers for diagnostic, prognostic, and therapeutic monitoring of…”
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Integrated Approach to Early Detection of Cardiovascular Toxicity Induced by a Ghrelin Receptor Agonist by Stokes, Alan H., Falls, J. Greg, Yoon, Lawrence, Cariello, Neal, Faiola, Brenda, Colton, Heidi M., Jordan, Holly L., Berridge, Brian R.

“…Cardiovascular (CV) safety concerns are among the leading causes of compound attrition in drug development. This work describes a strategy of applying novel…”
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Effect of estrous cycle phase on clinical pathology values in beagle dogs by Willson, Cynthia J., Chandra, Sundeep A., Kimbrough, Carie L., Jordan, Holly L.

“…Background In dogs, the diestrus phase is considerably longer than in most domestic animals, and is characterized by high circulating progesterone…”
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Acute ANIT Toxicity in Male IL-10 Knockout and Wild-type Mice by Faiola, Brenda, Peterson, Richard A., Kimbrough, Carrie L., Jordan, Holly L., Cullen, John M.

“…The innate immune response is known to modify hepatocellular injury induced by toxicants. To assess the role of IL-10, a component of the innate immune…”
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Effects of Solutol (Kolliphor) and Cremophor in Polyethylene Glycol 400 Vehicle Formulations in Sprague-Dawley Rats and Beagle Dogs by Stokes, Alan H., Kemp, Daniel C., Faiola, Brenda, Jordan, Holly L., Merrill, Christine L., Hailey, James R., Brown, Randy E., Bailey, David W.

“…When conventional vehicles (eg, methylcellulose and water) impart inadequate physical, chemical, and/or biological properties for proper toxicological…”
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Domestic Cat Model for Predicting Human Nucleoside Analogue Pharmacokinetics in Blood and Seminal Plasma by JORDAN, Holly L, PEREIRA, Arlene S, COHEN, Myron S, KASHUBA, Angela D. M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Thrombocytopenia in cats: a retrospective study of 41 cases by Jordan, J.L, Grindem, C.B, Breitschwerdt, E.B

“…The prevalence of feline thrombocytopenia (<200,000 platelets/m̈L) at North Carolina State University, College of Veterinary Medicine Teaching Hospital, from…”
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Response letter from Clinical Pathology Interest Group of the Society of Toxicologic Pathology (STP) for manuscript entitled International recommendations for training future toxicologic pathologists participating in regulatory-type, nonclinical toxicity studies by Bolon et al by Tripathi, Niraj K., Schultze, A. Eric, Pearson, Renee C., Everds, Nancy E., Elliott, Glenn S., Ramaiah, Lila, Wells, Monique Y., Latimer, Kenneth S., Walter, Gail L., Katavolos, Paula, Collins, Nathanial D., Tarrant, Jacqueline, Walker, Dana B., Topper, Michael J., Jordan, Holly L., O’Rourke, Laurie G., Guilpin, Valerie B., Brockus, Charles W., Wilcox, Angela L., Clemo, Frances A., Smith, Graham S., Reagan, William J., McCartney, Jeffrey E.

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Cytotoxic T lymphocytes specific for the simian immunodeficiency virus by Letvin, Norman L, Schmitz, Jörn E., Jordan, Holly L, Seth, Aruna, Hirsch, Vanessa M., Reimann, Keith A., Kuroda, Marcelo I.

“…A non‐human primate model for acquired immunodeficiency syndrome (AIDS), the simian immunodeficiency virus (SIV)‐infected rhesus monkey, was used to explore…”
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Detection of feline immunodeficiency virus RNA by two nucleic acid sequence based amplification (NASBA) formats by Jordan, Holly L., Scappino, Lori A., Moscardini, Mila, Pistello, Mauro

“…Feline immunodeficiency virus (FIV) is an AIDS-inducing lentivirus that infects domestic cats worldwide. Because of its clinicopathologic similarities to human…”
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Atlas of Comparative Diagnostic and Experimental Hematology, 2nd EditionCliffordSmithAlfredJarecki Blackwell Publishing, Ltd., Chichester, UK, ISBN: 978‐1‐4051‐7107‐6, hardcover, 152 pages, 2011, $99.99 by Jordan, Holly L.

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Detection of Simian Immunodeficiency Virus Gag-Specific CD8+ T Lymphocytes in Semen of Chronically Infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I-Peptide Complex by Jordan, H L, Kuroda, M J, Schmitz, J E, Steenbeke, T, Forman, M A, Letvin, N L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Distribution of immune cells in the female reproductive tract in uninfected and FIV infected cats by Butterworth, Jennifer L., English, Robert V., Jordan, Holly L., Tompkins, Mary B.

“…Cell-free and cell-associated FIV effectively cross the mucosa of the feline female reproductive tract. To identify possible cellular targets of FIV and to…”
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Elevated Interleukin-10-to-Interleukin-12 Ratio in Feline Immunodeficiency Virus-Infected Cats Predicts Loss of Type 1 Immunity to Toxoplasma gondii by Levy, Julie K., Ritchey, Jerry W., Rottman, James B., Davidson, Michael G., Liang, Ying-Hua, Jordan, Holly L., Tompkins, Wayne A., Tompkins, Mary B.

“…Similar to human immunodeficiency virus, feline immunodeficiency virus (FIV) induces immunodeficiency and enhanced susceptibility to secondary pathogens. To…”
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