Search Results - "Jordan, Crystal K."

Structure–activity relationships of triazolopyridine oxazole p38 inhibitors: Identification of candidates for clinical development by McClure, Kim F., Letavic, Michael A., Kalgutkar, Amit S., Gabel, Christopher A., Audoly, Laurent, Barberia, John T., Braganza, John F., Carter, Demetrius, Carty, Thomas J., Cortina, Santo R., Dombroski, Mark A., Donahue, Kathleen M., Elliott, Nancy C., Gibbons, Colleen P., Jordan, Crystal K., Kuperman, Alexander V., Labasi, Jeff M., LaLiberte, Ronald E., McCoy, Jennifer M., Naiman, Brian M., Nelson, Kendra L., Nguyen, Hang T., Peese, Kevin M., Sweeney, Francis J., Taylor, Timothy J., Trebino, Catherine E., Abramov, Yuriy A., Laird, Ellen R., Volberg, Walter A., Zhou, Jun, Bach, Justin, Lombardo, Franco

“…The synthesis, structure–activity relationship, in vivo activity, and metabolic profile for a series of triazolopyridine-oxazole based p38 inhibitors are…”
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Benzimidazolone p38 inhibitors by DOMBROSKI, Mark A, LETAVIC, Michael A, JORDAN, Crystal K, LABASI, Jeff M, MARTIN, William H, PEESE, Kevin M, STOCK, Ingrid A, SVENSSON, Linne, SWEENEY, Francis J, YU, Chul H, MCCLURE, Kim F, BARBERIA, John T, CARTY, Thomas J, CORTINA, Santo R, CSIKI, Csilla, DIPESA, Alan J, ELLIOTT, Nancy C, GABEL, Christopher A

“…The synthesis and in vitro p38 alpha activity of a novel series of benzimidazolone inhibitors is described. The p38 alpha SAR is consistent with a mode of…”
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Glutathione S-Transferase Omega 1-1 Is a Target of Cytokine Release Inhibitory Drugs and May Be Responsible for Their Effect on Interleukin-1 beta Posttranslational Processing by Laliberte, R E, Perregaux, D G, Hoth, L R, Rosner, P J, Jordan, C K, Peese, K M, Eggler, J, Dombroski, MA, Geoghegan, K F, Gabel, CA

“…Stimulus-induced posttranslational processing of human monocyte interleukin-1 beta (IL-1 beta ) is accompanied by major changes to the intracellular ionic…”
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Glutathione s-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing by Laliberte, Ronald E, Perregaux, David G, Hoth, Lise R, Rosner, Philip J, Jordan, Crystal K, Peese, Kevin M, Eggler, James F, Dombroski, Mark A, Geoghegan, Kieran F, Gabel, Christopher A

“…Stimulus-induced posttranslational processing of human monocyte interleukin-1beta (IL-1beta) is accompanied by major changes to the intracellular ionic…”
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Glutathione S-Transferase Omega 1-1 Is a Target of Cytokine Release Inhibitory Drugs and May Be Responsible for Their Effect on Interleukin-1β Posttranslational Processing by Ronald E. Laliberte, David G. Perregaux, Lise R. Hoth, Philip J. Rosner, Crystal K. Jordan, Kevin M. Peese, James. F. Eggler, Mark A. Dombroski, Kieran F. Geoghegan, Christopher A. Gabel

“…Stimulus-induced posttranslational processing of human monocyte interleukin-1β (IL-1β) is accompanied by major changes to the intracellular ionic…”
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Glutathione S-Transferase Omega 1-1 Is a Target of Cytokine Release Inhibitory Drugs and May Be Responsible for Their Effect on Interleukin-1औ Posttranslational Processing by Laliberte, Ronald E., Perregaux, David G., Hoth, Lise R., Rosner, Philip J., Jordan, Crystal K., Peese, Kevin M., Eggler, James.F., Dombroski, Mark A., Geoghegan, Kieran F., Gabel, Christopher A.

“…Stimulus-induced posttranslational processing of human monocyte interleukin-1औ (IL-1औ) is accompanied by major changes to the intracellular ionic environment,…”
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