Search Results - "Jordan, Ben T."

KSTAR: An algorithm to predict patient-specific kinase activities from phosphoproteomic data by Crowl, Sam, Jordan, Ben T., Ahmed, Hamza, Ma, Cynthia X., Naegle, Kristen M.

“…Kinase inhibitors as targeted therapies have played an important role in improving cancer outcomes. However, there are still considerable challenges, such as…”
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Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing by Leung, Szi Kay, Jeffries, Aaron R., Castanho, Isabel, Jordan, Ben T., Moore, Karen, Davies, Jonathan P., Dempster, Emma L., Bray, Nicholas J., O’Neill, Paul, Tseng, Elizabeth, Ahmed, Zeshan, Collier, David A., Jeffery, Erin D., Prabhakar, Shyam, Schalkwyk, Leonard, Jops, Connor, Gandal, Michael J., Sheynkman, Gloria M., Hannon, Eilis, Mill, Jonathan

“…Alternative splicing is a post-transcriptional regulatory mechanism producing distinct mRNA molecules from a single pre-mRNA with a prominent role in the…”
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Enhanced protein isoform characterization through long-read proteogenomics by Miller, Rachel M, Jordan, Ben T, Mehlferber, Madison M, Jeffery, Erin D, Chatzipantsiou, Christina, Kaur, Simi, Millikin, Robert J, Dai, Yunxiang, Tiberi, Simone, Castaldi, Peter J, Shortreed, Michael R, Luckey, Chance John, Conesa, Ana, Smith, Lloyd M, Deslattes Mays, Anne, Sheynkman, Gloria M

“…The detection of physiologically relevant protein isoforms encoded by the human genome is critical to biomedicine. Mass spectrometry (MS)-based proteomics is…”
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Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data by de Souza, Vladimir B C, Jordan, Ben T, Tseng, Elizabeth, Nelson, Elizabeth A, Hirschi, Karen K, Sheynkman, Gloria, Robinson, Mark D

“…Long-read RNA sequencing (lrRNA-seq) produces detailed information about full-length transcripts, including novel and sample-specific isoforms. Furthermore,…”
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Characterization of protein isoform diversity in human umbilical vein endothelial cells via long-read proteogenomics by Mehlferber, Madison M., Jeffery, Erin D., Saquing, Jamie, Jordan, Ben T., Sheynkman, Leon, Murali, Mayank, Genet, Gael, Acharya, Bipul R., Hirschi, Karen K., Sheynkman, Gloria M.

“…Endothelial cells (ECs) comprise the lumenal lining of all blood vessels and are critical for the functioning of the cardiovascular system. Their phenotypes…”
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IS-PRM-Based Peptide Targeting Informed by Long-Read Sequencing for Alternative Proteome Detection by Korchak, Jennifer A., Jeffery, Erin D., Bandyopadhyay, Saikat, Jordan, Ben T., Lehe, Micah D., Watts, Emily F., Fenix, Aidan, Wilhelm, Mathias, Sheynkman, Gloria M.

“…Alternative splicing is a major contributor of transcriptomic complexity, but the extent to which transcript isoforms are translated into stable, functional…”
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