Search Results - "Jorcano, Jose"

3D bioprinting of functional human skin: production and in vivo analysis by Cubo, Nieves, Garcia, Marta, Del Cañizo, Juan F, Velasco, Diego, Jorcano, Jose L

“…Significant progress has been made over the past 25 years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as…”
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Lidocaine-Loaded Solid Lipid Microparticles (SLMPs) Produced from Gas-Saturated Solutions for Wound Applications by López-Iglesias, Clara, Quílez, Cristina, Barros, Joana, Velasco, Diego, Alvarez-Lorenzo, Carmen, Jorcano, José L., Monteiro, Fernando J., García-González, Carlos A.

“…The delivery of bioactive agents using active wound dressings for the management of pain and infections offers improved performances in the treatment of wound…”
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In vitro and In vivo Wound Healing-Promoting Activities of Human Cathelicidin LL-37 by Carretero, Marta, Escámez, María J., García, Marta, Duarte, Blanca, Holguín, Almudena, Retamosa, Luisa, Jorcano, Jose L., Río, Marcela del, Larcher, Fernando

“…The human antimicrobial peptide LL-37 plays an important role in host defense against infection. In addition to its antimicrobial action, other activities have…”
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Differential Features between Chronic Skin Inflammatory Diseases Revealed in Skin-Humanized Psoriasis and Atopic Dermatitis Mouse Models by Carretero, Marta, Guerrero-Aspizua, Sara, Illera, Nuria, Galvez, Victoria, Navarro, Manuel, García-García, Francisco, Dopazo, Joaquin, Jorcano, Jose Luis, Larcher, Fernando, del Rio, Marcela

“…Psoriasis and atopic dermatitis are chronic and relapsing inflammatory diseases of the skin affecting a large number of patients worldwide. Psoriasis is…”
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Long-term Engraftment of Single Genetically Modified Human Epidermal Holoclones Enables Safety Pre-assessment of Cutaneous Gene Therapy by Larcher, Fernando, Dellambra, Elena, Rico, Laura, Bondanza, Sergio, Murillas, Rodolfo, Cattoglio, Claudia, Mavilio, Fulvio, Jorcano, José L, Zambruno, Giovanna, Del Rio, Marcela

“…Predicting the risks of permanent gene therapy approaches involving the use of integrative gene-targeting vectors has become a critical issue after the…”
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Skin and hair follicle integrity is crucially dependent on β1 integrin expression on keratinocytes by Brakebusch, Cord, Grose, Richard, Quondamatteo, Fabio, Ramirez, Angel, Jorcano, Jose L., Pirro, Alison, Svensson, Marcus, Herken, Rainer, Sasaki, Takako, Timpl, Rupert, Werner, Sabine, Fässler, Reinhard

“…β1 integrins are ubiquitously expressed receptors that mediate cell–cell and cell–extracellular matrix interactions. To analyze the function of β1 integrin in…”
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Hyaluronic acid-fibrin hydrogels show improved mechanical stability in dermo-epidermal skin substitutes by Montero, Andrés, Atienza, Clara, Elvira, Carlos, Jorcano, José Luis, Velasco, Diego

“…Human plasma-derived bilayered skin substitutes have been successfully used by our group in different skin tissue engineering applications. However, several…”
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Development of a Bioengineered Skin-Humanized Mouse Model for Psoriasis: Dissecting Epidermal-Lymphocyte Interacting Pathways by GUERRERO-ASPIZUA, Sara, GARCIA, Marta, LUIS JORCANO, Jose, LARCHER, Fernando, CARRETERO, Marta, DEL RIO, Marcela, MURILLAS, Rodolfo, RETAMOSA, Luisa, ILLERA, Nuria, DUARTE, Blanca, HOLGUIN, Almudena, PUIG, Susana, HERNANDEZ, Maria Isabel, MEANA, Alvaro

“…Over the past few years, whole skin xenotransplantation models that mimic different aspects of psoriasis have become available. However, these models are…”
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Deregulated Expression of Insulin-Like Growth Factor 1 in Prostate Epithelium Leads to Neoplasia in Transgenic Mice by DiGiovanni, John, Kiguchi, Kaoru, Frijhoff, Anita, Wilker, Eric, Bol, David K., Beltran, Linda, Moats, Samantha, Ramirez, Angel, Jorcano, Jose, Conti, Claudio

“…Transgenic mice expressing human insulin-like growth factor 1 (IGF-1) in basal epithelial cells of prostate have been characterized. Transgene expression led…”
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A keratin K5Cre transgenic line appropriate for tissue-specific or generalized cre-mediated recombination by Ramirez, Angel, Page, Angustias, Gandarillas, Alberto, Zanet, Jennifer, Pibre, Sophie, Vidal, Miguel, Tusell, Laura, Genesca, Anna, Whitaker, Duncan A., Melton, David W., Jorcano, Jose L.

“…We describe here a mouse line bearing a bovine keratin K5Cre recombinase transgene. These mice showed a dual pattern of Cre‐mediated recombination, depending…”
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Human plasma as a dermal scaffold for the generation of a completely autologous bioengineered skin by LLAMES, Sara G, DEL RIO, Marcela, LARCHER, Fernando, GARCIA, Eva, GARCIA, Marta, ESCAMEZ, Maria José, JORCANO, Jose L, HOLGUIN, Purificacion, MEANA, Alvaro

“…Keratinocyte cultures have been used for the treatment of severe burn patients. Here, we describe a new cultured bioengineered skin based on (1) keratinocytes…”
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Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor by GARCIA, Marta, FERNANDEZ-GARCIA, Nuria Isabel, LARCHER, Fernando, DEL RIO, Marcela, RIVAS, Veronica, CARRETERO, Marta, ESCAMEZ, Maria J, GONZALEZ-MARTIN, Alicia, MEDRANO, Estela E, VOLPERT, Olga, JORCANO, Jose L, JIMENEZ, Benilde

“…Human melanoma mortality is associated with the growth of metastasis in selected organs including the lungs, liver, and brain. In this study, we examined the…”
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Functional roles of Akt signaling in mouse skin tumorigenesis by SEGRELLES, Carmen, RUIZ, Sergio, JORCANO, Jose L, PARAMIO, Jesus M, PEREZ, Paloma, MURGA, Cristina, SANTOS, Mirentxu, BUDUNOVA, Irina V, MARTINEZ, Jesus, LARCHER, Fernando, SLAGA, Thomas J, GUTKIND, J. Silvio

“…The mouse skin carcinogenesis protocol is a unique model for understanding the molecular events leading to oncogenic transformation. Mutations in the Ha-ras…”
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Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development by KIGUCHI, Kaoru, BOL, David, CARBAJAL, Steve, BELTRAN, Linda, MOATS, Samantha, CHAN, Keith, JORCANO, José, DIGIOVANNI, John

“…The erbB family of receptor tyrosine kinases, which consists of the epidermal growth factor receptor (EGFr/erbB1), erbB2 (neu), erbB3 and erbB4, has been shown…”
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Remote diffuse reflectance spectroscopy sensor for tissue engineering monitoring based on blind signal separation by Martín-Mateos, Pedro, Crespo-Garcia, Sergio, Ruiz-Llata, Marta, Lopez-Fernandez, José Ramón, Jorcano, José Luis, Del Rio, Marcela, Larcher, Fernando, Acedo, Pablo

“…In this study the first results on evaluation and assessment of grafted bioengineered skin substitutes using an optical Diffuse Reflectance Spectroscopy (DRS)…”
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Contraction of fibrin‐derived matrices and its implications for in vitro human skin bioengineering by Montero, Andrés, Acosta, Sonia, Hernández, Rebeca, Elvira, Carlos, Jorcano, José Luis, Velasco, Diego

“…It is well‐known that fibroblasts play a fundamental role in the contraction of collagen and fibrin hydrogels when used in the production of in vitro bilayered…”
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Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion by DIGIOVANNI, J, BOL, D. K, WILKER, E, BELTRAN, L, CARBAJAL, S, MOATS, S, RAMIREZ, A, JORCANO, J, KIGUCHI, K

“…Transgenic mice overexpressing insulin-like growth factor-1 (IGF-1) in the basal layer of skin epidermis were generated using the bovine keratin 5 promoter…”
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ends of a conundrum by Paramio, Jesús M, Santos, Mirentxu, Jorcano, José L

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Real-Time Impedance Monitoring of Epithelial Cultures with Inkjet-Printed Interdigitated-Electrode Sensors by Mojena-Medina, Dahiana, Hubl, Moritz, Bäuscher, Manuel, Jorcano, José Luis, Ngo, Ha-Duong, Acedo, Pablo

“…From electronic devices to large-area electronics, from individual cells to skin substitutes, printing techniques are providing compelling applications in…”
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Interaction of a Migrating Cell Monolayer with a Flexible Fiber by Valencia, Leticia, López-Llorente, Verónica, Lasheras, Juan C., Jorcano, José L., Rodríguez-Rodríguez, Javier

“…Mechanical forces influence the development and behavior of biological tissues. In many situations, these forces are exerted or resisted by elastic compliant…”
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