Search Results - "Jophlin, Loretta L"

Theragnostic Efficacy of K18 Response in Alcohol Use Disorder with Clinically Significant Fibrosis Using Gut-Liver Axis by Sagaram, Manasa, Parthasarathy, Ranganathan, Condon, Sally L, Closson, Charles F, Kong, Maiying, Schwandt, Melanie L, Jophlin, Loretta L, Feng, Wenke, Barve, Ashutosh J, Vatsalya, Vatsalya

“…(1) Background: Fibrosis in early-stage alcohol-associated liver disease (ALD) is commonly under-diagnosed in routine clinical practice. This study…”
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Investigating the Acute Metabolic Effects of the N-Methyl Carbamate Insecticide, Methomyl, on Mouse Liver by Groswald, Amy M, Gripshover, Tyler C, Watson, Walter H, Wahlang, Banrida, Luo, Jianzhu, Jophlin, Loretta L, Cave, Matthew C

“…Many pesticides have been identified as endocrine and metabolism-disrupting chemicals with hepatotoxic effects. However, data are limited for insecticides in…”
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Past, Present, and Future Therapies for Alcohol-associated Hepatitis by Condon, Sally, Jophlin, Loretta L

“…Alcohol-associated hepatitis (AH) is a unique presentation of cholestatic steatohepatitis with liver dysfunction and malaise preceded by heavy alcohol intake…”
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Alcohol-Associated Liver Disease by Jophlin, Loretta L, Singal, Ashwani K, Shah, Vijay H

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ACG Clinical Guideline: Alcohol-Associated Liver Disease by Jophlin, Loretta L, Singal, Ashwani K, Bataller, Ramon, Wong, Robert J, Sauer, Bryan G, Terrault, Norah A, Shah, Vijay H

“…Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic disease and frequent indication for liver transplantation worldwide. With…”
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Provider Attitudes and Practices for Alcohol Screening, Treatment, and Education in Patients With Liver Disease: A Survey From the American Association for the Study of Liver Diseases Alcohol-Associated Liver Disease Special Interest Group by Im, Gene Y., Mellinger, Jessica L., Winters, Adam, Aby, Elizabeth S., Lominadze, Zurabi, Rice, John, Lucey, Michael R., Arab, Juan P., Goel, Aparna, Jophlin, Loretta L., Sherman, Courtney B., Parker, Richard, Chen, Po-Hung, Devuni, Deepika, Sidhu, Sandeep, Dunn, Winston, Szabo, Gyongyi, Singal, Ashwani K., Shah, Vijay H.

“…While abstinence-promoting behavioral and pharmacotherapies are part of the therapeutic foundation for alcohol use disorder (AUD) and alcohol-associated liver…”
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The Transcriptome of Hepatic Fibrosis Revealed by Single‐Cell RNA Sequencing by Jophlin, Loretta L., Cao, Sheng, Shah, Vijay H., Corey, Kathleen E., Malhi, Harmeet

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Hepatic stellate cells retain retinoid-laden lipid droplets after cellular transdifferentiation into activated myofibroblasts by Jophlin, Loretta L, Koutalos, Yiannis, Chen, Chunhe, Shah, Vijay, Rockey, Don C

“…Loss of retinyl ester (RE)-rich lipid droplets (LDs) from hepatic stellate cells (HSCs) is cited as a key event in their cellular transdifferentiation to…”
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Ectopic Esophageal Sebaceous Glands by Jophlin, Loretta L., Hartley, Christopher P., Katzka, David A.

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Positive blood phosphatidylethanol concentration is associated with unfavorable waitlist‐related outcomes for patients medically appropriate for liver transplantation by Faulkner, Claire S., White, Collin M., Manatsathit, Wuttiporn, Lamb, Bernadette, Vatsalya, Vatsalya, McClain, Craig J., Jophlin, Loretta L.

“…Background Excessive alcohol use is a leading etiology of liver disease and indication for liver transplantation. Accurate measurement of alcohol use remains a…”
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A single nucleotide polymorphism of PLIN2 is associated with nonalcoholic steatohepatitis and causes phenotypic changes in hepatocyte lipid droplets: A pilot study by Faulkner, Claire S., White, Collin M., Shah, Vijay H., Jophlin, Loretta L.

“…•rs35568725, coding Perilipin-2 Ser251Pro, may convey nonalcoholic steatohepatitis (NASH) risk.•18.2% of subjects with NASH versus 7.5% of healthy controls…”
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Increased Morbidity and Mortality of Patients with Non-cirrhotic Portal Vein Thrombosis After Abdominal and Pelvic Surgeries: a Study of the National Inpatient Sample 2002 to 2015 by Manatsathit, Wuttiporn, Patel, Kishan, Enke, Thomas, Sayles, Harlan, Jophlin, Loretta L., Merani, Shaheed

“…Background A higher rate of postoperative morbidity and mortality in patients with portal hypertension from cirrhosis is well recognized; however, the rate of…”
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Takotsubo cardiomyopathy following liver transplantation and COVID-19 infection by Winrich, Evan, Belur, Agastya D, Shine, Amal, Jophlin, Loretta L

“…Takotsubo cardiomyopathy involves transient systolic dysfunction of the left ventricle thought to be caused by a physiologic stress response and associated…”
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Takotsubo cardiomyopathy following acute liver failure by Jophlin, Loretta L., Koch, David G.

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Blood phosphatidylethanol (PEth) positivity associates with unfavorable waitlist-related outcomes for patients medically appropriate for liver transplant by Faulkner, Claire S., White, Collin M., Manatsathit, Wuttiporn, Lamb, Bernadette, Vatsalya, Vatsalya, McClain, Craig J., Jophlin, Loretta L.

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Provider Attitudes and Practices for Alcohol Screening, Treatment and Education in Patients with Liver Disease: a Survey from the AASLD ALD SIG by Im, Gene Y., Mellinger, Jessica L., Winters, Adam, Aby, Elizabeth S., Lominadze, Zurabi, Rice, John, Lucey, Michael R., Arab, Juan P, Goel, Aparna, Jophlin, Loretta L., Sherman, Courtney B., Parker, Richard, Chen, Po-Hung, Devuni, Deepika, Sidhu, Sandeep, Dunn, Winston, Szabo, Gyongyi, Singal, Ashwani K., Shah, Vijay H.

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Takotsubo cardiomyopathy following liver transplantation and COVID-19 infection by Winrich, Evan, Belur, Agastya D., Shine, Amal, Jophlin, Loretta L.

“…Takotsubo cardiomyopathy involves transient systolic dysfunction of the left ventricle thought to be caused by a physiologic stress response and associated…”
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Takotsubo cardiomyopathy following liver transplantation and COVID-19 infection by Winrich, Evan, Belur, Agastya D, Shine, Amal, Jophlin, Loretta L

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