Search Results - "Joosten, John A.F."

Identification of the Smallest Structure Capable of Evoking Opsonophagocytic Antibodies against Streptococcus pneumoniae Type 14 by Safari, Dodi, Dekker, Huberta A.T, Joosten, John A.F, Michalik, Dirk, de Souza, Adriana Carvalho, Adamo, Roberto, Lahmann, Martina, Sundgren, Andreas, Oscarson, Stefan, Kamerling, Johannis P, Snippe, Harm

“…Synthetic overlapping oligosaccharide fragments of Streptococcus pneumoniae serotype 14 capsular polysaccharide (Pn14PS), {6)-[β-D-Galp-(1[rightward…”
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Microwave-assisted, tin-mediated, regioselective 3- O-alkylation of galactosides by Ballell, Lluis, Joosten, John A.F., Maate, Fatna Ait el, Liskamp, Rob M.J., Pieters, Roland J.

“…A quick and efficient microwave-assisted one-pot 3- O-alkylation of galactosides is described. The efficiency is due to a combination of rapid…”
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Chemo-enzymatic synthesis of a tetra- and octasaccharide fragment of the capsular polysaccharide of Streptococcus pneumoniae type 14 by Joosten, John A.F, Kamerling, Johannis P, Vliegenthart, Johannes F.G

“…The chemo-enzymatic synthesis is described of tetrasaccharide β- d-Gal p-(1→4)-β- d-Glc p-(1→6)-[β- d-Gal p-(1→4)]-β- d-Glc pNAc-(1→O(CH 2) 6NH 2 ( 1) and…”
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Chemo-enzymatic synthesis of tetra-, penta-, and hexasaccharide fragments of the capsular polysaccharide of Streptococcus pneumoniae type 14 by Joosten, John A.F, Lazet, Bart J, Kamerling, Johannis P, Vliegenthart, Johannes F.G

“…The chemo-enzymatic synthesis is described of β- d-Glc p-(1→6)-[β- d-Gal p-(1→4)]-β- d-Glc pNAc-(1→3)-β- d-Gal p-(1→O(CH 2) 6NH 2 ( 1), β- d-Glc p-(1→6)-[β-…”
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Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985 by Elgersma, Ronald C, Coumans, Ruud G. E, Huijbregts, Tijl, Menge, Wiro M. P. B, Joosten, John A. F, Spijker, Henri J, de Groot, Franciscus M. H, van der Lee, Miranda M. C, Ubink, Ruud, van den Dobbelsteen, Diels J, Egging, David F, Dokter, Wim H. A, Verheijden, Gijs F. M, Lemmens, Jacques M, Timmers, C. Marco, Beusker, Patrick H

“…Antibody–drug conjugates (ADCs) that are currently on the market or in clinical trials are predominantly based on two drug classes: auristatins and…”
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High-Yielding Microwave-Assisted Synthesis of Triazole-Linked Glycodendrimers by Copper-Catalyzed [3+2] Cycloaddition by Joosten, John A. F., Tholen, Niels T. H., Ait El Maate, Fatna, Brouwer, Arwin J., van Esse, G. Wilma, Rijkers, Dirk T. S., Liskamp, Rob M. J., Pieters, Roland J.

“…A facile and high‐yielding synthesis of multivalent 1,4‐disubstituted 1,2,3‐triazole‐linked glycodendrimers is described. Azido carbohydrates are linked by a…”
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Inhibition of P-fimbriated Escherichia coli adhesion by multivalent galabiose derivatives studied by a live-bacteria application of surface plasmon resonance by Salminen, Annika, Loimaranta, Vuokko, Joosten, John A. F., Khan, A. Salam, Hacker, Jörg, Pieters, Roland J., Finne, Jukka

“…Objectives Uropathogenic P-fimbriated Escherichia coli adheres to host cells by specific adhesins recognizing galabiose (Galα1-4Gal)-containing structures on…”
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Inhibition of Streptococcus suis Adhesion by Dendritic Galabiose Compounds at Low Nanomolar Concentration by JOOSTEN, John A. F., LOIMARANTA, Vuokko, APPELDOORN, Chantal C. M., HAATAJA, Sauli, EL MAATE, Fatna Ait, LISKAMP, Rob M. J., FINNE, Jukka, PIETERS, Roland J.

“…A series of mono-, di-, and tetravalent galabiose (Galalpha1-4Gal) compounds were synthesized in good yields by coupling of a general carboxylic acid-bearing…”
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Novel multivalent mannose compounds and their inhibition of the adhesion of type 1 fimbriated uropathogenic E. coli by Appeldoorn, Chantal C.M., Joosten, John A.F., Ait el Maate, Fatna, Dobrindt, Ulrich, Hacker, Jörg, Liskamp, Rob M.J., Khan, A. Salam, Pieters, Roland J.

“…[Display omitted] A series of multivalent mannose containing compounds were prepared varying in size from small divalent, to 16-valent glycodenrimers and…”
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Use of tetravalent galabiose for inhibition of streptococcus suis serotype 2 infection in a mouse model by Pieters, Roland J, Slotved, Hans-Christian, Mortensen, Hanne Møller, Arler, Lene, Finne, Jukka, Haataja, Sauli, Joosten, John A F, Branderhorst, Hilbert M, Krogfelt, Karen A

“…Streptococcus suis is an important swine pathogen associated with a variety of infections such as meningitis, arthritis and septicemia. The bacterium is…”
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Synthesis of β-D-Galp-(1⇄4)-β-D-GlcpNAc-(1⇄2)-α-D-Manp-(1⇄O)(CH2)7CH3 Mimics to Explore the Substrate Specificity of Sialyltransferases and trans-Sialidases by Joosten, John A. F., Evers, Britta, Summeren, Ruben P. van, Kamerling, Johannis P., Vliegenthart, Johannes F. G.

“…Eleven trisaccharide octyl glycosides related to the N‐glycan sequence β‐D‐Galp‐(1⇄4)‐β‐D‐GlcpNAc‐(1⇄2)‐α‐D‐Manp‐(1⇄O)(CH2)7CH3 (1) designed for detailed…”
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Probing the substrate specificity of four different sialyltransferases using synthetic β- d-Gal p-(1 → 4)-β- d-Glc pNAc-(1 → 2)-α- d-Man p-(1 → O) (CH 2) 7CH 3 analogues by Rohfritsch, Philippe F., Joosten, John A.F., Krzewinski-Recchi, Marie-Ange, Harduin-Lepers, Anne, Laporte, Benoit, Juliant, Sylvie, Cerutti, Martine, Delannoy, Philippe, Vliegenthart, Johannes F.G., Kamerling, Johannis P.

“…The acceptor specificities of ST3Gal III, ST3Gal IV, ST6Gal I and ST6Gal II were investigated using a panel of β- d-Gal p-(1 → 4)-β- d-Glc pNAc-(1 → 2)-α-…”
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Probing the substrate specificity of four different sialyltransferases using synthetic β-d-Galp-(1→4)-β-d-GlcpNAc-(1→2)-α-d-Manp-(1→O) (CH2)7CH3 analogues by Rohfritsch, Philippe F., Joosten, John A.F., Krzewinski-Recchi, Marie-Ange, Harduin-Lepers, Anne, Laporte, Benoit, Juliant, Sylvie, Cerutti, Martine, Delannoy, Philippe, Vliegenthart, Johannes F.G., Kamerling, Johannis P.

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Probing the substrate specificity of four different sialyltransferases using synthetic beta-D-Galp-(1-->4)-beta-D-GlcpNAc-(1-->2)-alpha-D-Manp-(1-->O) (CH(2))7CH3 analogues general activating effect of replacing N-acetylglucosamine by N-propionylglucosamine by Rohfritsch, Philippe F, Joosten, John A F, Krzewinski-Recchi, Marie-Ange, Harduin-Lepers, Anne, Laporte, Benoit, Juliant, Sylvie, Cerutti, Martine, Delannoy, Philippe, Vliegenthart, Johannes F G, Kamerling, Johannis P

“…The acceptor specificities of ST3Gal III, ST3Gal IV, ST6Gal I and ST6Gal II were investigated using a panel of…”
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