Search Results - "Joost W. Gouw"

Quantitative Proteomics by Metabolic Labeling of Model Organisms by Gouw, Joost W., Krijgsveld, Jeroen, Heck, Albert J.R.

“…In the biological sciences, model organisms have been used for many decades and have enabled the gathering of a large proportion of our present day knowledge…”
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Metaproteomic and 16S rRNA Gene Sequencing Analysis of the Infant Fecal Microbiome by Cortes, Laetitia, Wopereis, Harm, Tartiere, Aude, Piquenot, Julie, Gouw, Joost W, Tims, Sebastian, Knol, Jan, Chelsky, Daniel

“…A metaproteomic analysis was conducted on the fecal microbiome of eight infants to characterize global protein and pathway expression. Although mass…”
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Highly Robust, Automated, and Sensitive Online TiO2-Based Phosphoproteomics Applied To Study Endogenous Phosphorylation in Drosophila melanogaster by Pinkse, Martijn W. H, Mohammed, Shabaz, Gouw, Joost W, van Breukelen, Bas, Vos, Harmjan R, Heck, Albert J. R

“…Reversible protein phosphorylation ranks among the most important post-translational modifications, and elucidation of phosphorylation sites is essential to…”
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Connexin multi-site phosphorylation: Mass spectrometry-based proteomics fills the gap by Chen, Vincent C., Gouw, Joost W., Naus, Christian C., Foster, Leonard J.

“…Connexins require an integrated network for protein synthesis, assembly, gating, internalization, degradation and feedback control that are necessary to…”
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Alternative reading frame selection mediated by a tRNA-like domain of an internal ribosome entry site by Ren, Qian, Wang, Qing S, Firth, Andrew E, Chan, Mandy M. Y, Gouw, Joost W, Guarna, M. Marta, Foster, Leonard J, Atkins, John F, Jan, Eric

“…The dicistrovirus intergenic region internal ribosome entry site (IRES) utilizes a unique mechanism, involving P-site tRNA mimicry, to directly assemble 80S…”
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In Vivo Stable Isotope Labeling of Fruit Flies Reveals Post-transcriptional Regulation in the Maternal-to-zygotic Transition by Gouw, Joost W., Pinkse, Martijn W.H., Vos, Harmjan R., Moshkin, Yuri, Verrijzer, C. Peter, Heck, Albert J.R., Krijgsveld, Jeroen

“…An important hallmark in embryonic development is characterized by the maternal-to-zygotic transition (MZT) where zygotic transcription is activated by a…”
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Straightforward and de Novo Peptide Sequencing by MALDI-MS/MS Using a Lys-N Metalloendopeptidase by Boersema, Paul J, Taouatas, Nadia, Altelaar, A F Maarten, Gouw, Joost W, Ross, Philip L, Pappin, Darryl J, Heck, Albert J R, Mohammed, Shabaz

“…In this work, we explore the potential of the metalloendopeptidase Lys-N for MALDI-MS/MS proteomics applications. Initially we digested a HEK293 cellular…”
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A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections by Ferreira, Rosana B R, Valdez, Yanet, Coombes, Brian K, Sad, Subash, Gouw, Joost W, Brown, Eric M, Li, Yuling, Grassl, Guntram A, Antunes, L Caetano M, Gill, Navkiran, Truong, Mimi, Scholz, Roland, Reynolds, Lisa A, Krishnan, Laskshmi, Zafer, Ahmed A, Sal-Man, Neta, Lowden, Michael J, Auweter, Sigrid D, Foster, Leonard J, Finlay, B Brett

“…Nontyphoidal Salmonella enterica (NTS) infections are a major burden to global public health, as they lead to diseases ranging from gastroenteritis to systemic…”
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Protein-bound and free glycation compounds in human milk: A comparative study with minimally processed infant formula and pasteurized bovine milk by Arena, Simona, De Pascale, Sabrina, Ciaravolo, Valentina, Monroy, Mariela Mejia, Gouw, Joost W., Stahl, Bernd, Bäuerl, Christine, Collado, Maria Carmen, De Filippo, Carlotta, Scaloni, Andrea, Troise, Antonio Dario

“…The role of the Maillard reaction and the accumulation of non-enzymatic glycation compounds in human milk have been scarcely considered. In this study, we…”
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MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics by Mortensen, Peter, Gouw, Joost W, Olsen, Jesper V, Ong, Shao-En, Rigbolt, Kristoffer T. G, Bunkenborg, Jakob, Cox, Jürgen, Foster, Leonard J, Heck, Albert J. R, Blagoev, Blagoy, Andersen, Jens S, Mann, Matthias

“…Mass spectrometry-based proteomics critically depends on algorithms for data interpretation. A current bottleneck in the rapid advance of proteomics technology…”
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Identification of peptides with tolerogenic potential in a hydrolysed whey‐based infant formula by Gouw, Joost W., Jo, Juandy, Meulenbroek, Laura A. P. M., Heijjer, T. Sam, Kremer, Erica, Sandalova, Elena, Knulst, André C., Jeurink, Prescilla V., Garssen, Johan, Rijnierse, Anneke, Knippels, Léon M. J.

“…Summary Background Failure to induce oral tolerance may result in food allergy. Hydrolysed cow's milk‐based infant formulas are recommended in subjects with a…”
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Monitoring of changes in the membrane proteome during stationary phase adaptation of Bacillus subtilis using in vivo labeling techniques by Dreisbach, Annette, Otto, Andreas, Becher, Dörte, Hammer, Elke, Teumer, Alexander, Gouw, Joost W, Hecker, Michael, Völker, Uwe

“…Bacillus subtilis has been developed as a model system for physiological proteomics. However, thus far these studies have mainly been limited to cytoplasmic,…”
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A horizontally acquired transcription factor coordinates Salmonella adaptations to host microenvironments by Brown, Nat F, Rogers, Lindsay D, Sanderson, Kristy L, Gouw, Joost W, Hartland, Elizabeth L, Foster, Leonard J

“…The transcription factors HilA and SsrB activate expression of two type III secretion systems (T3SSs) and cognate effectors that reprogram host cell functions…”
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Expression clustering reveals detailed co-expression patterns of functionally related proteins during B cell differentiation: a proteomic study using a combination of one-dimensional gel electrophoresis, LC-MS/MS, and stable isotope labeling by amino acids in cell culture (SILAC) by Romijn, Edwin P, Christis, Chantal, Wieffer, Marnix, Gouw, Joost W, Fullaondo, Asier, van der Sluijs, Peter, Braakman, Ineke, Heck, Albert J R

“…B cells play an essential role in the immune response. Upon activation they may differentiate into plasma cells that secrete specific antibodies against…”
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MSQuant: a platform for stable isotope-based quantitative proteomics by Gouw, Joost W, Krijgsveld, Jeroen

“…Quantitative approaches in proteomics are emerging as a powerful tool to probe the dynamics of protein expression across biological conditions. Thereby,…”
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Derivatization of small oligosaccharides prior to analysis by matrix-assisted laser desorption/ionization using glycidyltrimethylammonium chloride and Girard's reagent T by Gouw, Joost W., Burgers, Peter C., Trikoupis, Moschoula A., Terlouw, Johan K.

“…In matrix‐assisted laser desorption/ionization (MALDI) analyses of small oligosaccharides a very large increase in sensitivity (by a factor of 1000) may be…”
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Optimizing Identification and Quantitation of 15N-Labeled Proteins in Comparative Proteomics by Gouw, Joost W, Tops, Bastiaan B. J, Mortensen, Peter, Heck, Albert J. R, Krijgsveld, Jeroen

“…Comparative proteomics has emerged as a powerful approach to determine differences in protein abundance between biological samples. The introduction of…”
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Metabolic labeling of model organisms using heavy nitrogen (15N) by Gouw, Joost W, Tops, Bastiaan B J, Krijgsveld, Jeroen

“…Quantitative proteomics aims to identify and quantify proteins in cells or organisms that have been obtained from different biological origin (e.g., "healthy…”
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Expression Clustering Reveals Detailed Co-expression Patterns of Functionally Related Proteins during B Cell Differentiation by Romijn, Edwin P., Christis, Chantal, Wieffer, Marnix, Gouw, Joost W., Fullaondo, Asier, van der Sluijs, Peter, Braakman, Ineke, Heck, Albert J.R.

“…B cells play an essential role in the immune response. Upon activation they may differentiate into plasma cells that secrete specific antibodies against…”
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Alternative reading frame selection mediated by a tRNA-like domain of an internal ribosome entry site by Ren, Qian, Wang, Qing S., Firth, Andrew E., Chan, Mandy M. Y., Gouw, Joost W., Guarna, M. Marta, Foster, Leonard J., Atkins, John F., Jan, Eric

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