Search Results - "Joosse, M E"

Malignancy and mortality in paediatric‐onset inflammatory bowel disease: a 3‐year prospective, multinational study from the paediatric IBD Porto group of ESPGHAN by Joosse, M. E., Aardoom, M. A., Kemos, P., Turner, D., Wilson, D. C., Koletzko, S., Martin‐de‐Carpi, J., Fagerberg, U. L., Spray, C., Tzivinikos, C., Sladek, M., Shaoul, R., Roma‐Giannikou, E., Bronsky, J., Serban, D. E., Ruemmele, F. M., Garnier‐Lengline, H., Veres, G., Hojsak, I., Kolho, K. L., Davies, I. H., Aloi, M., Lionetti, P., Hussey, S., Veereman, G., Braegger, C. P., Trindade, E., Wewer, A. V., Hauer, A. C., Vries, A. C. H., Sigall Boneh, R., Sarbagili Shabat, C., Levine, A., Ridder, L.

“…Summary Background Risk benefit strategies in managing inflammatory bowel diseases (IBD) are dependent upon understanding the risks of uncontrolled…”
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IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4+ T cells: relevance to inflammatory bowel disease by Veenbergen, S., Li, P., Raatgeep, H. C., Lindenbergh-Kortleve, D. J., Simons-Oosterhuis, Y., Farrel, A., Costes, L. M. M., Joosse, M. E., van Berkel, L. A., de Ruiter, L. F., van Leeuwen, M. A., Winter, D., Holland, S. M., Freeman, A. F., Wakabayashi, Y., Zhu, J., de Ridder, L., Driessen, G. J., Escher, J. C., Leonard, W. J., Samsom, J. N.

“…Uncontrolled interferon γ (IFNγ)-mediated T-cell responses to commensal microbiota are a driver of inflammatory bowel disease (IBD). Interleukin-10 (IL-10) is…”
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Invasive fungal infections in patients treated with Bruton's tyrosine kinase inhibitors by Dunbar, A, Joosse, M E, de Boer, F, Eefting, M, Rijnders, B J A

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P063 Expression of the coinhibitory receptor TIGIT on memory CD4+ T cells is induced by TCR ligation and retinoic acid co-stimulation and is elicited during microbial colonization of the intestine by Barendregt, D, Joosse, M E, van Berkel, L A, van Schoonhoven, A, Samsom, J N

“…Abstract Background The coinhibitory receptor T cell immunoglobulin and ITIM domain (TIGIT) is widely expressed by immune cells, including CD4+ T cells…”
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P045 TIGIT expression differentiates regulatory from inflammatory Th1 gut-homing effector CD4+ T cells in inflammatory bowel disease patients by Heredia, M, Costes, L M M, Tindemans, I, Aardoom, M A, Klomberg, R C W, Kemos, P, Joosse, M E, van Haaften, D H, Tuk, B, Ruemmele, F, Croft, N M, Escher, J C, de Ridder, L, Samsom, J N

“…Abstract Background Crohn’s disease (CD) and ulcerative colitis (UC) are characterized by intestinal infiltration of pathogenic effector CD4+ T cells. The…”
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P069 Elevated adaptive immune responses to multiple Lachnospiraceae bacterial flagellins in therapy-naïve pediatric CD patients are associated with distinct immune pathology by Barendregt, D, Joosse, M E, Alexander, K L, Costes, L M M, Tindemans, I, Simons-Oosterhuis, Y, Aardoom, M A, Klomberg, R C W, Heredia, M, Hulleman- van Haaften, D H, Tuk, B, Nugteren, S, Doukas, M, Escher, J C, de Ridder, L, Elson, C O, Samsom, J N

“…Abstract Background In inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), CD4+ T cell-responses to unknown microbial…”
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DOP09 IgG responses to multiple bacterial flagellins identify a subgroup of paediatric therapy-naive Crohn’s disease patients with increased microbiota-specific T-cell reactivity by Costes, L, Tindemans, I, Joosse, M E, Aardoom, M A, Jongsma, M M E, Raatgeep, R H C, van Haaften, D H, Alexander, K L, Duck, L W, Heikema, A P, Kemos, P, Escher, J C, Ruemmele, F M, Croft, N M, Elson, C O, de Ridder, L, Samsom, J N

“…Abstract Background inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic intestinal disease driven by…”
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Recurrent cholangitis in a 65-year-old man. Biliary papillomatosis by Joosse, M E, Schipper, M E I, Libbrecht, L, van Buuren, H R, de Man, R A

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