Search Results - "Joo-Yeon Hwang"
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In Silico identification of a common mobile element insertion in exon 4 of RP1
Published in Scientific reports (28-06-2021)“…Mobile element insertions (MEIs) typically exceed the read lengths of short-read sequencing technologies and are therefore frequently missed. Recently, a…”
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2
Activating Transcription Factor 3 Is a Target Molecule Linking Hepatic Steatosis to Impaired Glucose Homeostasis
Published in Journal of hepatology (01-08-2017)“…Graphical abstract Summarized effects of ATF3 and in vivo -jetPEI ATF3 siRNA on the oxidative stress-mediated hepatic steatosis and/or T2D…”
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3
Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus
Published in Scientific reports (05-10-2018)“…Genome-wide DNA methylation has been implicated in complex human diseases. Here, we identified epigenetic biomarkers for type 2 diabetes (T2D) underlying…”
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4
Chronic Ethanol Consumption Inhibits Glucokinase Transcriptional Activity by Atf3 and Triggers Metabolic Syndrome in Vivo
Published in The Journal of biological chemistry (26-09-2014)“…Chronic ethanol consumption induces pancreatic β-cell dysfunction through glucokinase (Gck) nitration and down-regulation, leading to impaired glucose…”
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5
Genome-wide association study identifies GYS2 as a novel genetic factor for polycystic ovary syndrome through obesity-related condition
Published in Journal of human genetics (01-10-2012)“…To investigate the role of genetic predisposition in the pathogenesis of polycystic ovary syndrome (PCOS) in relation to obesity, we performed a genome-wide…”
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The Korean undiagnosed diseases program: lessons from a one-year pilot project
Published in Orphanet journal of rare diseases (20-03-2019)“…The Korean Undiagnosed Diseases Program (KUDP) was launched in January 2017 as a one-year pilot project to address the increasing global interest in patients…”
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7
Male-specific genetic effect on hypertension and metabolic disorders
Published in Human genetics (01-03-2014)“…Genetic risk factors for hypertension may have age or gender specificity and pleiotropic effects. This study aims to measure the risk of genetic and…”
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New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population
Published in Journal of human genetics (01-06-2013)“…Most recently, 1-h hyperglycemia has been recognized as an additional risk factor for type 2 diabetes. To date, previous genome-wide association studies for…”
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9
Gene and dietary calcium interaction effects on brachial–ankle pulse wave velocity
Published in Clinical nutrition (Edinburgh, Scotland) (01-10-2016)“…Summary Background & aim Understanding the lifestyle and genetic factors that affect pulse wave velocity (PWV) may provide clues to preventing atherosclerotic…”
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10
Spin Axis Precession of LARES Measured by Satellite Laser Ranging
Published in IEEE geoscience and remote sensing letters (01-03-2014)“…Satellite laser ranging (SLR) is an efficient technique to measure spin parameters of the fully passive satellite LARES. Analysis of the laser range…”
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HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia
Published in Bone (New York, N.Y.) (01-12-2009)“…Abstract Introduction Endogenous glucocorticoid (GC) may participate in bone physiology, even in subjects with no glucocorticoid excess. 11β-hydroxysteroid…”
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12
A large-scale replication study for the association of rs17039192 in HIF-2α with knee osteoarthritis
Published in Journal of orthopaedic research (01-08-2012)“…Osteoarthritis (OA) is a common disease with a genetic component for its etiology. Recently, a genetic association of a single nucleotide polymorphism (SNP),…”
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13
Genome-wide association study identifies two novel Loci with sex-specific effects for type 2 diabetes mellitus and glycemic traits in a korean population
Published in Diabetes & metabolism journal (01-10-2014)“…Until recently, genome-wide association study (GWAS)-based findings have provided a substantial genetic contribution to type 2 diabetes mellitus (T2DM) or…”
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14
Recapitulation of previous genome-wide association studies with two distinct pathophysiological entities of gastric cancer in the Korean population
Published in Journal of human genetics (01-04-2013)“…Gastric cancer (GC) is the most common malignancy. The incidence rates remain remarkably high in East Asians. Although genome-wide association studies in the…”
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15
Association of ADIPOR1 polymorphisms with bone mineral density in postmenopausal Korean women
Published in Experimental & molecular medicine (30-06-2012)“…Adiponectin may affect bone through interactions with two known receptors, adiponectin receptors (ADIPOR) 1 and 2. We examined the association between…”
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Large-scale genome-wide association studies in east Asians identify new genetic loci influencing metabolic traits
Published in Nature genetics (01-10-2011)“…To identify the genetic bases for nine metabolic traits, we conducted a meta-analysis combining Korean genome-wide association results from the KARE project (n…”
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17
Iron Chelator Triggers Inflammatory Signals in Human Intestinal Epithelial Cells: Involvement of p38 and Extracellular Signal-Regulated Kinase Signaling Pathways
Published in The Journal of immunology (1950) (01-06-2004)“…Competition for cellular iron (Fe) is a vital component of the interaction between host and pathogen. Most bacteria have an obligate requirement for Fe to…”
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18
Obesity-related CpG Methylation (cg07814318) of Kruppel-like Factor-13 (KLF13) Gene with Childhood Obesity and its cis-Methylation Quantitative Loci
Published in Scientific reports (16-05-2017)“…The cg07814318 hypermethylation of Kruppel-like factor 13 ( KLF13 ) gene has been reported for its relevancy with Body Mass Index (BMI) from European origin…”
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19
Performance Analysis of the First Korean Satellite Laser Ranging System
Published in Journal of astronomy and space sciences (01-09-2014)“…The first Korean satellite laser ranging (SLR) system, Daedeok SLR station (DAEK station) was developed by Korea Astronomy and Space Science Institute (KASI)…”
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20
Purification and characterization of Aspergillus oryzae LK-101 salt-tolerant acid protease isolated from soybean paste
Published in Food science and biotechnology (01-04-2010)“…A novel salt-tolerant acid protease was produced from Aspergillus oryzae LK-101 (AOLK-101). The AOLK-101 protease was purified to homogeneity by ammonium…”
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