Search Results - "Jonz, Michael G"
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Neurochemical Signalling Associated With Gill Oxygen Sensing and Ventilation: A Receptor Focused Mini-Review
Published in Frontiers in physiology (13-07-2022)“…Despite the large body of work describing vertebrate ventilatory responses to hypoxia, remarkably little is known about the receptors and afferent pathways…”
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Single-cell transcriptomic analysis of neuroepithelial cells and other cell types of the gills of zebrafish (Danio rerio) exposed to hypoxia
Published in Scientific reports (16-06-2022)“…The fish gill is a multifunctional organ involved in numerous physiological processes, such as gas exchange and sensing of hypoxia by respiratory…”
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Purinergic and Cholinergic Drugs Mediate Hyperventilation in Zebrafish: Evidence from a Novel Chemical Screen
Published in PloS one (21-04-2016)“…A rapid test to identify drugs that affect autonomic responses to hypoxia holds therapeutic and ecologic value. The zebrafish (Danio rerio) is a convenient…”
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Neuroepithelial oxygen chemoreceptors of the zebrafish gill
Published in The Journal of physiology (01-11-2004)“…In aquatic vertebrates, hypoxia induces physiological changes that arise principally from O 2 chemoreceptors of the gill. Neuroepithelial cells (NECs) of the…”
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Development of oxygen sensing in the gills of zebrafish
Published in Journal of experimental biology (01-04-2005)“…Previous studies have described the morphology, innervation and O(2)-chemoreceptive properties of neuroepithelial cells (NECs) of the zebrafish gill filaments…”
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Cell proliferation and regeneration in the gill
Published in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (01-10-2024)“…Seminal studies from the early 20th century defined the structural changes associated with development and regeneration of the gills in goldfish at the gross…”
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Confocal imaging of Merkel-like basal cells in the taste buds of zebrafish
Published in Acta histochemica (01-02-2012)“…The oropharyngeal cavity in fish supports a range of sensory modalities, including detection of chemical and mechanical stimuli. Taste buds are found…”
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A comparative perspective on lung and gill regeneration
Published in Journal of experimental biology (01-10-2020)“…The ability to continuously grow and regenerate the gills throughout life is a remarkable property of fish and amphibians. Considering that gill regeneration…”
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Insights into the evolution of polymodal chemoreceptors
Published in Acta histochemica (01-10-2018)“…Respiratory chemoreceptors in vertebrates are specialized cells that detect chemical changes in the environment or arterial blood supply and initiate autonomic…”
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Proton-Mediated Feedback Inhibition of Presynaptic Calcium Channels at the Cone Photoreceptor Synapse
Published in The Journal of neuroscience (20-04-2005)“…Generation of center-surround antagonistic receptive fields in the outer retina occurs via inhibitory feedback modulation of presynaptic voltage-gated calcium…”
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11
Proton modulation of ion channels in isolated horizontal cells of the goldfish retina
Published in The Journal of physiology (01-06-2007)“…Transient changes in extracellular pH (pH o ) occur in the retina and may have profound effects on neurotransmission and visual processing due to the pH…”
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A role for dopamine in control of the hypoxic ventilatory response via D 2 receptors in the zebrafish gill
Published in Journal of comparative neurology (1911) (01-02-2024)“…Dopamine is a neurotransmitter involved in oxygen sensing and control of reflex hyperventilation. In aquatic vertebrates, oxygen sensing occurs in the gills…”
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Goldfish and crucian carp are natural models of anoxia tolerance in the retina
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-08-2022)“…Vertebrates need oxygen to survive. The central nervous system has an especially high energy demand, so brain and retinal neurons quickly die in anoxia. But…”
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Identification of oxygen-sensitive neuroepithelial cells through an endogenous reporter gene in larval and adult transgenic zebrafish
Published in Cell and tissue research (01-04-2021)“…In teleost fish, specialized oxygen (O 2 ) chemoreceptors, called neuroepithelial cells (NECs), are found in the gill epithelium in adults. During development,…”
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Mitochondrial KATP channels stabilize intracellular Ca2+ during hypoxia in retinal horizontal cells of goldfish ( Carassius auratus )
Published in Journal of experimental biology (15-09-2021)“…Neurons of the retina require oxygen to survive. In hypoxia, neuronal ATP production is impaired, ATP-dependent ion pumping is reduced, transmembrane ion…”
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Replacement of mitochondrion-rich cells during regeneration of the gills and opercular epithelium in zebrafish (Danio rerio)
Published in Acta histochemica (01-07-2021)“…Transport epithelia maintain the volume, ion concentration and acid-base balance of blood and extracellular fluids. In teleost fish, mitochondrion-rich cells…”
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17
A role for dopamine in control of the hypoxic ventilatory response via D2 receptors in the zebrafish gill
Published in Journal of comparative neurology (1911) (01-02-2024)“…Dopamine is a neurotransmitter involved in oxygen sensing and control of reflex hyperventilation. In aquatic vertebrates, oxygen sensing occurs in the gills…”
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18
Identification of signalling pathways involved in gill regeneration in zebrafish
Published in Journal of experimental biology (15-01-2024)“…The occurrence of regeneration of the organs involved in respiratory gas exchange amongst vertebrates is heterogeneous. In some species of amphibians and…”
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Characterization of ion channels and O 2 sensitivity in gill neuroepithelial cells of the anoxia-tolerant goldfish ( Carassius auratus )
Published in Journal of neurophysiology (01-12-2017)“…The neuroepithelial cell (NEC) of the fish gill is an important model for O sensing in vertebrates; however, a complete picture of the chemosensory mechanisms…”
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Regeneration of the gill filaments and replacement of serotonergic neuroepithelial cells in adult zebrafish (Danio rerio)
Published in Respiratory physiology & neurobiology (01-03-2020)“…•Using live imaging and immunohistochemistry we describe regeneration in the gills of the model vertebrate, the zebrafish.•The gill filaments retain a…”
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