Search Results - "Jonigk, Danny D."

Dual role of GRHL3 in bladder carcinogenesis depending on histological subtypes by Lammert, Franziska C., Pannhausen, Julia, Noetzel, Erik, Friedland, Florian, Wirtz, Julia, Herfs, Yannick, Leypold, Sophie, Gan, Lin, Weiskirchen, Ralf, Schnitzler, Tician, Knüchel, Ruth, Maurer, Jochen, Jonigk, Danny D., Rose, Michael, Gaisa, Nadine T.

“…The effect of grainyhead‐like transcription factor 3 (GRHL3) on cancer development depends on the cancer subtypes as shown in tumor entities such as colorectal…”
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Time-Dependent Molecular Motifs of Pulmonary Fibrogenesis in COVID-19 by Kamp, Jan C, Neubert, Lavinia, Ackermann, Maximilian, Stark, Helge, Werlein, Christopher, Fuge, Jan, Haverich, Axel, Tzankov, Alexandar, Steinestel, Konrad, Friemann, Johannes, Boor, Peter, Junker, Klaus, Hoeper, Marius M, Welte, Tobias, Laenger, Florian, Kuehnel, Mark P, Jonigk, Danny D

“…(1) Background: In COVID-19 survivors there is an increased prevalence of pulmonary fibrosis of which the underlying molecular mechanisms are poorly…”
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The Adult Sprague-Dawley Sugen-Hypoxia Rat Is Still "the One:" A Model of Group 1 Pulmonary Hypertension: Reply to Le Cras and Abman by Bogaard, Harm J, Legchenko, Ekaterina, Ackermann, Maximilian, Kühnel, Mark P, Jonigk, Danny D, Chaudhary, Ketul R, Sun, Xiaoqing, Stewart, Duncan J, Hansmann, Georg

“…The authors reply to Le Cras and Abman stating that the Adult Sprague-Dawley Sugen-hypoxia rat is still a model of Group 1 pulmonary hypertension. Kojonazarov…”
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Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection by Lee, Amanda J, Feng, Emily, Chew, Marianne V, Balint, Elizabeth, Poznanski, Sophie M, Giles, Elizabeth, Zhang, Ali, Marzok, Art, Revill, Spencer D, Vahedi, Fatemeh, Dubey, Anisha, Ayaub, Ehab, Jimenez-Saiz, Rodrigo, McGrath, Joshua J C, Ritchie, Tyrah M, Jordana, Manel, Jonigk, Danny D, Ackermann, Maximilian, Ask, Kjetil, Miller, Matthew, Richards, Carl D, Ashkar, Ali A

“…The ability to treat severe viral infections is limited by our understanding of the mechanisms behind virus-induced immunopathology. While the role of type I…”
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Fibrosis-Related Gene Profiling in Liver Biopsies of PiZZ α1-Antitrypsin Children with Different Clinical Courses by Kamp, Jan C, Kappe, Naomi N, Moro, Carlos Fernández, Fuge, Jan, Kuehnel, Mark P, Wrenger, Sabine, Welte, Tobias, Hoek, Bart van, Jonigk, Danny D, Khedoe, Padmini P S J, Strnad, Pavel, Björnstedt, Mikael, Stolk, Jan, Janciauskiene, Sabina, Nemeth, Antal

“…PiZZ (Glu342Lys) α1-antitrypsin deficiency (AATD) is characterized by intrahepatic AAT polymerization and is a risk factor for liver disease development in…”
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Insights Into Immunothrombotic Mechanisms in Acute Stroke due to Vaccine-Induced Immune Thrombotic Thrombocytopenia by de Buhr, Nicole, Baumann, Tristan, Werlein, Christopher, Fingerhut, Leonie, Imker, Rabea, Meurer, Marita, Götz, Friedrich, Bronzlik, Paul, Kühnel, Mark P, Jonigk, Danny D, Ernst, Johanna, Leotescu, Andrei, Gabriel, Maria M, Worthmann, Hans, Lichtinghagen, Ralf, Tiede, Andreas, von Köckritz-Blickwede, Maren, Falk, Christine S, Weissenborn, Karin, Schuppner, Ramona, Grosse, Gerrit M

“…During the COVID-19 pandemic, vaccination is the most important countermeasure. Pharmacovigilance concerns however emerged with very rare, but potentially…”
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Vitamin A regulates tissue-specific organ remodeling in diet-induced obesity independent of mitochondrial function by Shymotiuk, Ivanna, Froese, Natali, Werlein, Christopher, Naasner, Lea, Szaroszyk, Malgorzata, Kühnel, Mark P, Jonigk, Danny D, Blaner, William S, Wende, Adam R, Abel, E Dale, Bauersachs, Johann, Riehle, Christian

“…Perturbed mitochondrial energetics and vitamin A (VitA) metabolism are associated with the pathogenesis of diet-induced obesity (DIO) and type 2 diabetes…”
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The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling by Ackermann, Maximilian, Kamp, Jan C., Werlein, Christopher, Walsh, Claire L., Stark, Helge, Prade, Verena, Surabattula, Rambabu, Wagner, Willi L., Disney, Catherine, Bodey, Andrew J., Illig, Thomas, Leeming, Diana J., Karsdal, Morten A., Tzankov, Alexandar, Boor, Peter, Kühnel, Mark P., Länger, Florian P., Verleden, Stijn E., Kvasnicka, Hans M., Kreipe, Hans H., Haverich, Axel, Black, Stephen M., Walch, Axel, Tafforeau, Paul, Lee, Peter D., Hoeper, Marius M., Welte, Tobias, Seeliger, Benjamin, David, Sascha, Schuppan, Detlef, Mentzer, Steven J., Jonigk, Danny D.

“…COVID-19 is characterized by a heterogeneous clinical presentation, ranging from mild symptoms to severe courses of disease. 9–20% of hospitalized patients…”
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Hypoxia Attenuates Pressure Overload-Induced Heart Failure by Froese, Natali, Szaroszyk, Malgorzata, Galuppo, Paolo, Visker, Joseph R, Werlein, Christopher, Korf-Klingebiel, Mortimer, Berliner, Dominik, Reboll, Marc R, Hamouche, Rana, Gegel, Simona, Wang, Yong, Hofmann, Winfried, Tang, Ming, Geffers, Robert, Wende, Adam R, Kühnel, Mark P, Jonigk, Danny D, Hansmann, Georg, Wollert, Kai C, Abel, E Dale, Drakos, Stavros G, Bauersachs, Johann, Riehle, Christian

“…Alveolar hypoxia is protective in the context of cardiovascular and ischemic heart disease; however, the underlying mechanisms are incompletely understood. The…”
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A multiscale X-ray phase-contrast tomography dataset of a whole human left lung by Xian, R. Patrick, Walsh, Claire L., Verleden, Stijn E., Wagner, Willi L., Bellier, Alexandre, Marussi, Sebastian, Ackermann, Maximilian, Jonigk, Danny D., Jacob, Joseph, Lee, Peter D., Tafforeau, Paul

“…Technological advancements in X-ray imaging using bright and coherent synchrotron sources now allows the decoupling of sample size and resolution while…”
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Comparative Analysis of Gene Expression in Fibroblastic Foci in Patients with Idiopathic Pulmonary Fibrosis and Pulmonary Sarcoidosis by Kamp, Jan C, Neubert, Lavinia, Stark, Helge, Hinrichs, Jan B, Boekhoff, Caja, Seidel, Allison D, Ius, Fabio, Haverich, Axel, Gottlieb, Jens, Welte, Tobias, Braubach, Peter, Laenger, Florian, Hoeper, Marius M, Kuehnel, Mark P, Jonigk, Danny D

“…Fibroblastic foci (FF) are characteristic features of usual interstitial pneumonia (UIP)/idiopathic pulmonary fibrosis (IPF) and one cardinal feature thought…”
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Circulating microRNAs in Symptomatic and Asymptomatic Carotid Stenosis by Grosse, Gerrit M, Derda, Anselm A, Stauss, Ricarda D, Neubert, Lavinia, Jonigk, Danny D, Kühnel, Mark P, Gabriel, Maria M, Schuppner, Ramona, Wilhelmi, Mathias, Bär, Christian, Bauersachs, Johann, Schrimpf, Claudia, Thum, Thomas, Weissenborn, Karin

“…Specific microRNAs (miRs) have been implicated in the pathophysiology of atherosclerosis and may represent interesting diagnostic and therapeutic targets in…”
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Microvascular placental alterations in maternal COVID-19 by Ackermann, Maximilian, Jonigk, Danny D.

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Reply to Bush et al. and to Persson by Ackermann, Maximilian, Mentzer, Steven J, Jonigk, Danny D

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A potential new biomarker in HNSCC: metastasis suppressor protein 1 (MTSS1) by Klein, Maurice, Wermker, Kai, Rashad, Ashkan, Fischer, Henrike J., Jonigk, Danny D., Hölzle, Frank, Cacchi, Claudio

“…Metastasis suppressor protein 1 (MTSS1) is a prognostic tumour marker in different malignant epithelial tumour entities and previously mainly the MTSS1…”
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The Bronchial Circulation in COVID-19 Pneumonia by Ackermann, Maximilian, Tafforeau, Paul, Wagner, Willi L, Walsh, Claire L, Werlein, Christopher, Kühnel, Mark P, Länger, Florian P, Disney, Catherine, Bodey, Andrew J, Bellier, Alexandre, Verleden, Stijn E, Lee, Peter D, Mentzer, Steven J, Jonigk, Danny D

“…The primary life-limiting pulmonary morbidity of severe coronavirus disease (COVID-19) is characterized by pulmonary endothelialitis, microangiopathy, and…”
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Distribution and volume of mitochondria in alveolar epithelial type 1 cells in infant and adult human lungs by Schierz, Arne K., Rößler, Giacomo, Schneider, Jan Philipp, Tschanz, Stefan A., Werlein, Christopher, Jonigk, Danny D., Schipke, Julia, Mühlfeld, Christian

“…Alveolar epithelial type I (AE1) cells with their wide spatial expansion form approximately 95% of the outer surface area of the air-blood barrier inside the…”
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The Challenge of Long-Term Cultivation of Human Precision-Cut Lung Slices by Preuß, Eike B., Schubert, Stephanie, Werlein, Christopher, Stark, Helge, Braubach, Peter, Höfer, Anne, Plucinski, Edith K.J., Shah, Harshit R., Geffers, Robert, Sewald, Katherina, Braun, Armin, Jonigk, Danny D., Kühnel, Mark P.

“…Human precision-cut lung slices (PCLS) have proven to be an invaluable tool for numerous toxicologic, pharmacologic, and immunologic studies. Although a…”
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The metalloproteinase ADAM10 sheds angiotensin‐converting enzyme (ACE) from the pulmonary endothelium as a soluble, functionally active convertase by Webers, Maria, Yu, Yan, Eyll, Johanna, Vanderliek‐Kox, Julia, Schun, Katharina, Michely, Anna, Schumertl, Tim, Garbers, Christoph, Dietrich, Jana, Jonigk, Danny D., Krüger, Ingo, Kühnel, Mark P., Martin, Christian, Ludwig, Andreas, Düsterhöft, Stefan

“…The renin‐angiotensin‐aldosterone system (RAAS) plays a critical role in the regulation of blood pressure and fluid balance, with angiotensin‐converting enzyme…”
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Multidimensional Analysis of the Adult Human Heart in Health and Disease Using Hierarchical Phase-Contrast Tomography by Brunet, Joseph, Cook, Andrew C, Walsh, Claire L, Cranley, James, Tafforeau, Paul, Engel, Klaus, Arthurs, Owen, Berruyer, Camille, Burke O'Leary, Emer, Bellier, Alexandre, Torii, Ryo, Werlein, Christopher, Jonigk, Danny D, Ackermann, Maximilian, Dollman, Kathleen, Lee, Peter D

“…Background Current clinical imaging modalities such as CT and MRI provide resolution adequate to diagnose cardiovascular diseases but cannot depict detailed…”
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