Search Results - "Jongsma, Geartsje"

High levels of S100A8/A9 proteins aggravate ventilator-induced lung injury via TLR4 signaling by Kuipers, Maria T, Vogl, Thomas, Aslami, Hamid, Jongsma, Geartsje, van den Berg, Elske, Vlaar, Alexander P J, Roelofs, Joris J T H, Juffermans, Nicole P, Schultz, Marcus J, van der Poll, Tom, Roth, Johannes, Wieland, Catharina W

“…Bacterial products add to mechanical ventilation in enhancing lung injury. The role of endogenous triggers of innate immunity herein is less well understood…”
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Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury by Kuipers, Maria T, Aslami, Hamid, Vlaar, Alexander P J, Juffermans, Nicole P, Tuip-de Boer, Anita M, Hegeman, Maria A, Jongsma, Geartsje, Roelofs, Joris J T H, van der Poll, Tom, Schultz, Marcus J, Wieland, Catharina W

“…Uric acid released from injured tissue is considered a major endogenous danger signal and local instillation of uric acid crystals induces acute lung…”
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The Extent of Ventilator-Induced Lung Injury in Mice Partly Depends on Duration of Mechanical Ventilation by Hegeman, Maria A., Hemmes, Sabrine N. T., Kuipers, Maria T., Bos, Lieuwe D. J., Jongsma, Geartsje, Roelofs, Joris J. T. H., van der Sluijs, Koenraad F., Juffermans, Nicole P., Vroom, Margreeth B., Schultz, Marcus J.

“…Background. Mechanical ventilation (MV) has the potential to initiate ventilator-induced lung injury (VILI). The pathogenesis of VILI has been primarily…”
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High-Dose Acetylsalicylic Acid Is Superior to Low-Dose as Well as to Clopidogrel in Preventing Lipopolysaccharide-Induced Lung Injury in Mice by Tuinman, Pieter R., Müller, Marcella C., Jongsma, Geartsje, Hegeman, Maria A., Juffermans, Nicole P.

“…BACKGROUNDUse of aspirin (acetylsalicylic acid [ASA]) was found to improve outcome in animal models of acute lung injury (ALI) or its more severe form, acute…”
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Abcg5/8 Independent Biliary Cholesterol Excretion in Atp8b1-Deficient Mice by Groen, Annemiek, Kunne, Cindy, Jongsma, Geartsje, van den Oever, Karin, Mok, Kam S, Petruzzelli, Michele, Vrins, Carlos L.J, Bull, Laura, Paulusma, Coen C, Oude Elferink, Ronald P.J

“…Backgrounds & Aims: ATP8B1 is a phosphatidylserine flippase in the canalicular membrane; patients with mutations in ATP8B1 develop severe chronic (PFIC1) or…”
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TLR2 Deficiency Aggravates Lung Injury Caused by Mechanical Ventilation by Kuipers, Maria Theresa, Jongsma, Geartsje, Hegeman, Maria A, Tuip-de Boer, Anita M, Wolthuis, Esther K, Choi, Goda, Bresser, Paul, van der Poll, Tom, Schultz, Marcus J, Wieland, Catharina W

“…ABSTRACTInnate immunity pathways are found to play an important role in ventilator-induced lung injury. We analyzed pulmonary expression of Toll-like receptor…”
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The receptor for advanced glycation end products in ventilator-induced lung injury by Kuipers, Maria T, Aslami, Hamid, Tuinman, Pieter Roel, Tuip-de Boer, Anita M, Jongsma, Geartsje, van der Sluijs, Koenraad F, Choi, Goda, Wolthuis, Esther K, Roelofs, Joris JTH, Bresser, Paul, Schultz, Marcus J, van der Poll, Tom, Wieland, Catharina W

“…Background Mechanical ventilation (MV) can cause ventilator-induced lung injury (VILI). The innate immune response mediates this iatrogenic inflammatory…”
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High Levels of S100A8/A9 Proteins Aggravate Ventilator-Induced Lung Injury via TLR4 Signaling. e68694 by Kuipers, Maria T, Vogl, Thomas, Aslami, Hamid, Jongsma, Geartsje, Berg, Elske vanden, Vlaar, Alexander PJ, Roelofs, J TH, Juffermans, Nicole P, Schultz, Marcus J, Poll, Tom vander

“…Background Bacterial products add to mechanical ventilation in enhancing lung injury. The role of endogenous triggers of innate immunity herein is less well…”
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