Search Results - "Jonges, L"

Toward a data‐driven evaluation of the 2010 American College of Rheumatology/European League Against Rheumatism criteria for rheumatoid arthritis: Is it sensible to look at levels of rheumatoid factor? by van der Linden, M. P. M., Batstra, M. R., Bakker‐Jonges, L. E., Detert, J., Bastian, H., Scherer, H. U., Toes, R. E. M., Burmester, G.‐R., Mjaavatten, M. D., Kvien, T. K., Huizinga, T. W. J., van der Helm‐van Mil, A. H. M.

“…Objective Recently, new classification criteria for rheumatoid arthritis (RA) have been devised by methodology that used first a quantitative approach (data…”
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Women with rheumatoid arthritis negative for anti-cyclic citrullinated peptide and rheumatoid factor are more likely to improve during pregnancy, whereas in autoantibody-positive women autoantibody levels are not influenced by pregnancy by de Man, Y A, Bakker-Jonges, L E, Goorbergh, C M Dufour-van den, Tillemans, S P R, Hooijkaas, H, Hazes, J M W, Dolhain, R J E M

“…To determine whether changes in levels of anti-cyclic citrullinated peptide (anti-CCP) and rheumatoid factor (RF) are associated with the spontaneous…”
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Anti-cyclic citrullinated peptide positivity in non-rheumatoid arthritis disease samples: citrulline-dependent or not? by Vannini, A, Cheung, K, Fusconi, M, Stammen-Vogelzangs, J, Drenth, J P H, Dall’Aglio, A C, Bianchi, F B, Bakker-Jonges, L E, van Venrooij, W J, Pruijn, G J M, Zendman, A J W

“…Background: Antibodies directed against citrullinated proteins (eg anti-cyclic citrullinated peptide (CCP)) have excellent diagnostic and good prognostic…”
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B-cell maturation and antibody responses in individuals carrying a mutated CD19 allele by Artac, H, Reisli, I, Kara, R, Pico-Knijnenburg, I, Adin-Çinar, S, Pekcan, S, Jol-van der Zijde, C M, van Tol, M J D, Bakker-Jonges, L E, van Dongen, J J M, van der Burg, M, van Zelm, M C

“…Homozygous CD19 mutations lead to an antibody deficiency due to disruption of the CD19 complex and consequent impaired signaling by the B-cell antigen…”
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Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells by GEUTSKENS, S. B, VAN DER EB, M. M, PLOMP, A. C, JONGES, L. E, CRAMER, S. J, ENSINK, N. G, KUPPEN, P. J. K, HOEBEN, R. C

“…The host-immune response against adenoviruses forms a major obstacle for their use as gene therapy vectors for treatment of genetic defects. None the less,…”
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Efficient direct priming of tumor-specific cytotoxic T lymphocyte in vivo by an engineered APC by SCHOENBERGER, S. P, JONGES, L. E, MOOIJAART, R. J. D, HARTGERS, F, TOES, R. E. M, KAST, W. M, MELIEF, C. J. M, OFFRINGA, R

“…Although numerous studies have documented a role for B7-1 (CD80) in the induction of antitumor CTL immunity, it is presently unclear to what extent expression…”
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The Phenotypic Heterogeneity of Human Natural Killer Cells: Presence of at least 48 Different Subsets in the Peripheral Blood by Jonges, L. E., Albertsson, P., Van Vlierberghe, R. L. P., Ensink, N. G., Johansson, B. R., Van De Velde, C. J. H., Fleuren, G. J., Nannmark, U., Kuppen, P. J. K.

“…Peripheral blood natural killer (NK) cells are usually defined as a homogeneous cell population. However, NK cells show heterogeneous expression of a diversity…”
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Caspase-3 Activity as a Prognostic Factor in Colorectal Carcinoma by Jonges, Liesbeth E, Nagelkerke, J Fred, Ensink, N Geeske, van der Velde, Edo A, Tollenaar, Rob A E M, Fleuren, Gert Jan, van de Velde, Cornelis J H, Morreau, Hans, Kuppen, Peter J K

“…Several techniques to determine apoptotic frequencies in tumors have been described. In this study, we report that biochemical detection of enzymatic caspase-3…”
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Matrix metalloproteinases of human NK cells by Albertsson, P, Kim, M H, Jonges, L E, Kitson, R P, Kuppen, P J, Johansson, B R, Nannmark, U, Goldfarb, R H

“…We have previously reported that MMP-2 and MMP-9 are present in rat A-NK cells, and have recently documented that additional MMPs are present in rodent A-NK…”
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Liver and tumour tissue concentrations of TNF-alpha in cancer patients treated with TNF-alpha and melphalan by isolated liver perfusion by KUPPEN, PJK, JONGES, LE, VAN DE VELDE, CJH, VAHRMEIJER, AL, TOLLENAAR, RAEM, BOREL RINKES, IHM, EGGERMONT, AMM

“…In this study we determined the level of tumour necrosis factor alpha (TNF-alpha) in liver and tumour tissue samples obtained from patients with colorectal…”
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Tumor structure and extracellular matrix as a possible barrier for therapeutic approaches using immune cells or adenoviruses in colorectal cancer by Kuppen, P J, van der Eb, M M, Jonges, L E, Hagenaars, M, Hokland, M E, Nannmark, U, Goldfarb, R H, Basse, P H, Fleuren, G J, Hoeben, R C, van de Velde, C J

“…In this article we report about the role that tumor structure and extracellular matrix (ECM) may play in immunotherapy and in gene therapy using adenoviruses…”
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Role of NK cells in adoptive immunotherapy of metastatic colorectal cancer in a syngeneic rat model by Kuppen, Peter J. K., Gorter, Arko, Hagenaars, Martin, Jonges, Liesbeth E., Giezeman-Smits, Katinka M., Nagelkerke, J. Fred, Fleuren, Gertjan, Van De Velde, Cornelis J. H.

“…This article reviews our immunotherapy research with natural killer (NK) cells in a syngeneic rat colorectal cancer liver and lung metastasis model. Using…”
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Novel monoclonal antibodies against membrane structures that are preferentially expressed on IL-2-activated rat NK cells by Giezeman‐Smits, Katinka M., Jonges, Liesbeth E., Chambers, William H., Brisette‐Storkus, Cynthia S., Vlierberghe, Ronald L. P., Eendenburg, Jaap D. H., Eggermont, Alexander M. M., Fleuren, Gert Jan, Kuppen, Peter J. K.

“…Interleukin‐2 (IL‐2)‐activated natural killer (NK) cells are known to mediate specific functions such as cytolytic activity and tumor infiltration more…”
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NK Cells Modulate MHC Class I Expression on Tumor Cells and their Susceptibility to Lysis by Jonges, Liesbeth E., Giezeman-Smits, Katinka M., Van Vlierberghe, Ronald LP, Ensink, NGeeske, Hagenaars, Martin, Joly, étienne, Eggermont, Alexander MM, Van De Velde, Cornelis JH, Fleuren, Gert Jan, Kuppen, Peter JK

“…Cytotoxicity and production of cytokines are two important functions of NK cellsThese two different NK functions were studied in a syngeneic rat model in…”
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Translating the MDS flow cytometric score into clinical practice by Heron, M, Dovern, E, Bakker-Jonges, L E, Posthuma, E F M, Brouwer, R E, Smedts, F, Batstra, M R

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IgA antibodies directed against cytoplasmic antigens of polymorphonuclear leukocytes in patients with Henoch-Schoenlein purpura by vd Wall Bake, A W, Lobatto, S, Jonges, L, Daha, M R, van Es, L A

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A retrospective study on the role of antibodies against soluble liver antigen (anti-SLA antibodies) and other autoantibodies in the diagnostics of autoimmune hepatitis by Bakker-Jonges, L E, ter Borg, P C J, van Buuren, H R, Hooijkaas, H

“…To determine the diagnostic value of antibodies against soluble liver antigen (anti-SLA antibodies) and a number of other antibodies for the diagnosis…”
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The development of a bi-specific anti-CD161A x anti-tumor antibody for rat NK cell targeting by Hagenaars, M, Ensink, N G, Jonges, L E, Chambers, W H, Eggermont, A M, van de Velde, C J, Fleuren, G J, Kuppen, P J

“…In order to improve the therapeutic efficacy of adoptive immunotherapy of cancer using IL-2-activated NK (A-NK) cells, we developed a bi-specific monoclonal…”
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Evaluation of serological markers to differentiate between ulcerative colitis and Crohn's disease: pANCA, ASCA and agglutinating antibodies to anaerobic coccoid rods by Linskens, Ronald K, Mallant-Hent, Rosalie C, Groothuismink, Z M. Anthonie, Bakker-Jonges, Liesbeth E, van de Merwe, Joop P, Hooijkaas, Herbert, von Blomberg, B Mary E, Meuwissen, Stephan G. M

“…BACKGROUND Accurate diagnosis of inflammatory bowel disease, in particular the differentiation between ulcerative colitis and Crohn's disease, is important for…”
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A basal membrane-like structure surrounding tumour nodules may prevent intraepithelial leucocyte infiltration in colorectal cancer by MENON, Anand G, FLEUREN, Gert Jan, ALPHENAAR, Ellen A, JONGES, Liesbeth E, VAN RHIJN, Connie M, ENSINK, N. Geeske, PUTTER, Hein, TOLLENAAR, Rob A. E. M, VAN DE VELDE, Cornelis J. H, KUPPEN, Peter J. K

“…Epithelial tumours consist of an epithelial compartment and a stromal compartment, which are sometimes separated by a basal membrane-like structure. We sought…”
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