Search Results - "Jongeneel, C. Victor"

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma by Nikolaev, Sergey I, Rimoldi, Donata, Iseli, Christian, Valsesia, Armand, Robyr, Daniel, Gehrig, Corinne, Harshman, Keith, Guipponi, Michel, Bukach, Olesya, Zoete, Vincent, Michielin, Olivier, Muehlethaler, Katja, Speiser, Daniel, Beckmann, Jacques S, Xenarios, Ioannis, Halazonetis, Thanos D, Jongeneel, C Victor, Stevenson, Brian J, Antonarakis, Stylianos E

“…Sergey Nikolaev, Stylianos Antonarakis and colleagues report exome sequencing of seven melanoma cell lines and matched germline cells. They identify recurring…”
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Ten simple rules for developing bioinformatics capacity at an academic institution by Aron, Shaun, Jongeneel, C Victor, Chauke, Paballo Abel, Chaouch, Melek, Kumuthini, Judit, Zass, Lyndon, Radouani, Fouzia, Kassim, Samar Kamal, Fadlelmola, Faisal M, Mulder, Nicola

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H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa by Mulder, Nicola J, Adebiyi, Ezekiel, Alami, Raouf, Benkahla, Alia, Brandful, James, Doumbia, Seydou, Everett, Dean, Fadlelmola, Faisal M, Gaboun, Fatima, Gaseitsiwe, Simani, Ghazal, Hassan, Hazelhurst, Scott, Hide, Winston, Ibrahimi, Azeddine, Jaufeerally Fakim, Yasmina, Jongeneel, C Victor, Joubert, Fourie, Kassim, Samar, Kayondo, Jonathan, Kumuthini, Judit, Lyantagaye, Sylvester, Makani, Julie, Mansour Alzohairy, Ahmed, Masiga, Daniel, Moussa, Ahmed, Nash, Oyekanmi, Ouwe Missi Oukem-Boyer, Odile, Owusu-Dabo, Ellis, Panji, Sumir, Patterton, Hugh, Radouani, Fouzia, Sadki, Khalid, Seghrouchni, Fouad, Tastan Bishop, Özlem, Tiffin, Nicki, Ulenga, Nzovu

“…The application of genomics technologies to medicine and biomedical research is increasing in popularity, made possible by new high-throughput genotyping and…”
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Genome-wide analysis of cancer/testis gene expression by Hofmann, Oliver, Caballero, Otavia L, Stevenson, Brian J, Chen, Yao-Tseng, Cohen, Tzeela, Chua, Ramon, Maher, Christopher A, Panji, Sumir, Schaefer, Ulf, Kruger, Adele, Lehvaslaiho, Minna, Carninci, Piero, Hayashizaki, Yoshihide, Jongeneel, C. Victor, Simpson, Andrew J.G, Old, Lloyd J, Hide, Winston

“…Cancer/Testis (CT) genes, normally expressed in germ line cells but also activated in a wide range of cancer types, often encode antigens that are immunogenic…”
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Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform by Blatti, 3rd, Charles, Emad, Amin, Berry, Matthew J, Gatzke, Lisa, Epstein, Milt, Lanier, Daniel, Rizal, Pramod, Ge, Jing, Liao, Xiaoxia, Sobh, Omar, Lambert, Mike, Post, Corey S, Xiao, Jinfeng, Groves, Peter, Epstein, Aidan T, Chen, Xi, Srinivasan, Subhashini, Lehnert, Erik, Kalari, Krishna R, Wang, Liewei, Weinshilboum, Richard M, Song, Jun S, Jongeneel, C Victor, Han, Jiawei, Ravaioli, Umberto, Sobh, Nahil, Bushell, Colleen B, Sinha, Saurabh

“…We present Knowledge Engine for Genomics (KnowEnG), a free-to-use computational system for analysis of genomics data sets, designed to accelerate biomedical…”
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Developing reproducible bioinformatics analysis workflows for heterogeneous computing environments to support African genomics by Baichoo, Shakuntala, Souilmi, Yassine, Panji, Sumir, Botha, Gerrit, Meintjes, Ayton, Hazelhurst, Scott, Bendou, Hocine, Beste, Eugene de, Mpangase, Phelelani T, Souiai, Oussema, Alghali, Mustafa, Yi, Long, O'Connor, Brian D, Crusoe, Michael, Armstrong, Don, Aron, Shaun, Joubert, Fourie, Ahmed, Azza E, Mbiyavanga, Mamana, Heusden, Peter van, Magosi, Lerato E, Zermeno, Jennie, Mainzer, Liudmila Sergeevna, Fadlelmola, Faisal M, Jongeneel, C Victor, Mulder, Nicola

“…The Pan-African bioinformatics network, H3ABioNet, comprises 27 research institutions in 17 African countries. H3ABioNet is part of the Human Health and…”
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Indexing strategies for rapid searches of short words in genome sequences by Iseli, Christian, Ambrosini, Giovanna, Bucher, Philipp, Jongeneel, C Victor

“…Searching for matches between large collections of short (14-30 nucleotides) words and sequence databases comprising full genomes or transcriptomes is a common…”
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A View on Genomic Medicine Activities in Africa: Implications for Policy by Jongeneel, C Victor, Kotze, Maritha J, Bhaw-Luximon, Archana, Fadlelmola, Faisal M, Fakim, Yasmina J, Hamdi, Yosr, Kassim, Samar Kamal, Kumuthini, Judit, Nembaware, Victoria, Radouani, Fouzia, Tiffin, Nicki, Mulder, Nicola

“…Genomics policy development involves assessing a wide range of issues extending from specimen collection and data sharing to whether and how to utilize…”
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Rapid evolution of cancer/testis genes on the X chromosome by Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, Simpson, Andrew J, Jongeneel, C Victor

“…Cancer/testis (CT) genes are normally expressed only in germ cells, but can be activated in the cancer state. This unusual property, together with the finding…”
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Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma by Valsesia, Armand, Rimoldi, Donata, Martinet, Danielle, Ibberson, Mark, Benaglio, Paola, Quadroni, Manfredo, Waridel, Patrice, Gaillard, Muriel, Pidoux, Mireille, Rapin, Blandine, Rivolta, Carlo, Xenarios, Ioannis, Simpson, Andrew J G, Antonarakis, Stylianos E, Beckmann, Jacques S, Jongeneel, C Victor, Iseli, Christian, Stevenson, Brian J

“…Cancer genomes frequently contain somatic copy number alterations (SCNA) that can significantly perturb the expression level of affected genes and thus disrupt…”
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Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes by Deutsch, Samuel, Lyle, Robert, Dermitzakis, Emmanouil T., Attar, Homa, Subrahmanyan, Lakshman, Gehrig, Corinne, Parand, Leila, Gagnebin, Maryline, Rougemont, Jacques, Jongeneel, C. Victor, Antonarakis, Stylianos E.

“…Inter-individual differences in gene expression are likely to account for an important fraction of phenotypic differences, including susceptibility to common…”
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Numerous potentially functional but non-genic conserved sequences on human chromosome 21 by Antonarakis, Stylianos E, Dermitzakis, Emmanouil T, Reymond, Alexandre, Lyle, Robert, Scamuffa, Nathalie, Ucla, Catherine, Deutsch, Samuel, Stevenson, Brian J, Flegel, Volker, Bucher, Philipp, Jongeneel, C. Victor

“…The use of comparative genomics to infer genome function relies on the understanding of how different components of the genome change over evolutionary time…”
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Similarities and differences of polyadenylation signals in human and fly by Retelska, Dorota, Iseli, Christian, Bucher, Philipp, Jongeneel, C Victor, Naef, Felix

“…Cleavage of messenger RNA (mRNA) precursors is an essential step in mRNA maturation. The signal recognized by the cleavage enzyme complex has been…”
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Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data by Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, Jongeneel, C Victor, Valgeirsson, Haukur, Fenwick, Kerry, Iravani, Marjan, Leao, Maria, Simpson, Andrew J G, Strausberg, Robert L, Jat, Parmjit S, Ashworth, Alan, Neville, A Munro, O'Hare, Michael J

“…Diverse microarray and sequencing technologies have been widely used to characterise the molecular changes in malignant epithelial cells in breast cancers…”
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eVOC: a controlled vocabulary for unifying gene expression data by Kelso, Janet, Visagie, Johann, Theiler, Gregory, Christoffels, Alan, Bardien, Soraya, Smedley, Damian, Otgaar, Darren, Greyling, Gary, Jongeneel, C Victor, McCarthy, Mark I, Hide, Tania, Hide, Winston

“…Expression data contribute significantly to the biological value of the sequenced human genome, providing extensive information about gene structure and the…”
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Identification of Cancer/Testis-Antigen Genes by Massively Parallel Signature Sequencing by Chen, Yao-Tseng, Scanlan, Matthew J., Venditti, Charis A., Chua, Ramon, Theiler, Gregory, Stevenson, Brian J., Iseli, Christian, Gure, Ali O., Vasicek, Tom, Strausberg, Robert L., Jongeneel, C. Victor, Old, Lloyd J., Andrew J. G. Simpson

“…Massively parallel signature sequencing (MPSS) generates millions of short sequence tags corresponding to transcripts from a single RNA preparation. Most MPSS…”
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Comprehensive Sampling of Gene Expression in Human Cell Lines with Massively Parallel Signature Sequencing by Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, Harris, Robert A., O'Hare, Michael J., Neville, A. Munro, Andrew J. G. Simpson, Strausberg, Robert L.

“…Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and…”
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Vertebrate conserved non coding DNA regions have a high persistence length and a short persistence time by Retelska, Dorota, Beaudoing, Emmanuel, Notredame, Cédric, Jongeneel, C Victor, Bucher, Philipp

“…The comparison of complete genomes has revealed surprisingly large numbers of conserved non-protein-coding (CNC) DNA regions. However, the biological function…”
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Long-range heterogeneity at the 3' ends of human mRNAs by Iseli, Christian, Stevenson, Brian J, de Souza, Sandro J, Samaia, Helena B, Camargo, Anamaria A, Buetow, Kenneth H, Strausberg, Robert L, Simpson, Andrew J G, Bucher, Philipp, Jongeneel, C Victor

“…The publication of a draft of the human genome and of large collections of transcribed sequences has made it possible to study the complex relationship between…”
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Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome by Chen, Yao-Tseng, Iseli, Christian, Venditti, Charis A., Old, Lloyd J., Simpson, Andrew J. G., Jongeneel, C. Victor

“…Cancer/testis (CT) genes are normally expressed in germ cells only, yet are reactivated and expressed in some tumors. Of the approximately 40 CT genes or gene…”
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