Search Results - "Jonge, Wouter J."

The Multifaceted Role of Serotonin in Intestinal Homeostasis by Koopman, Nienke, Katsavelis, Drosos, Hove, Anne S Ten, Brul, Stanley, Jonge, Wouter J de, Seppen, Jurgen

“…The monoamine serotonin, 5-hydroxytryptamine (5-HT), is a remarkable molecule with conserved production in prokaryotes and eukaryotes and a wide range of…”
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Non‐invasive transcutaneous auricular vagus nerve stimulation prevents postoperative ileus and endotoxemia in mice by Hong, Gun‐Soo, Zillekens, Anne, Schneiker, Bianca, Pantelis, Dimitrios, Jonge, Wouter J., Schaefer, Nico, Kalff, Joerg C., Wehner, Sven

“…Background The cholinergic anti‐inflammatory pathway comprises the perception of peripheral inflammation by afferent sensory neurons and reflex activation of…”
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Consensus on the definition of colorectal anastomotic leakage: A modified Delphi study by van Helsdingen, Claire Pm, Jongen, Audrey Chm, de Jonge, Wouter J, Bouvy, Nicole D, Derikx, Joep Pm

“…Despite the emerging knowledge about colorectal anastomotic leakage (CAL) through the increasing number of clinical and experimental studies, there is no…”
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Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn’s disease by Diederen, Kay, Li, Jia V., Donachie, Gillian E., de Meij, Tim G., de Waart, Dirk R., Hakvoort, Theodorus B. M., Kindermann, Angelika, Wagner, Josef, Auyeung, Victoria, te Velde, Anje A., Heinsbroek, Sigrid E. M., Benninga, Marc A., Kinross, James, Walker, Alan W., de Jonge, Wouter J., Seppen, Jurgen

“…A nutritional intervention, exclusive enteral nutrition (EEN) can induce remission in patients with pediatric Crohn’s disease (CD). We characterized changes in…”
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Exploring the Immunomodulatory Potential of Human Milk: Aryl Hydrocarbon Receptor Activation and Its Impact on Neonatal Gut Health by Wieser, Naomi V, Ghiboub, Mohammed, Verseijden, Caroline, van Goudoever, Johannes B, Schoonderwoerd, Anne, de Meij, Tim G J, Niemarkt, Hendrik J, Davids, Mark, Lefèvre, Antoine, Emond, Patrick, Derikx, Joep P M, Jonge, Wouter J de, Sovran, Bruno

“…Several metabolites of the essential amino acid tryptophan have emerged as key players in gut homeostasis through different cellular pathways, particularly…”
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The clinical and economical impact of postoperative ileus in patients undergoing colorectal surgery by Peters, Emmeline G., Pattamatta, Madhuri, Smeets, Boudewijn J. J., Brinkman, Daan J., Evers, Silvia M. A. A., Jonge, Wouter J., Hiligsmann, Mickaël, Luyer, Misha D. P.

“…Background Colorectal surgery is associated with postoperative ileus (POI). Despite its widespread manifestation, the influence of POI on recovery, quality of…”
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Human salivary peptide histatin‐1 stimulates epithelial and endothelial cell adhesion and barrier function by Dijk, Irene A., Laura Ferrando, Maria, Wijk, Anne‐Eva, Hoebe, Ron A., Nazmi, Kamran, Jonge, Wouter J., Krawczyk, Przemek M., Bolscher, Jan G. M., Veerman, Enno C. I., Stap, Jan

“…ABSTRACT Histatins are multifunctional histidine‐rich peptides secreted by the salivary glands and exclusively present in the saliva of higher primates, where…”
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Vagal innervation is required for the formation of tertiary lymphoid tissue in colitis by Olivier, Brenda J., Cailotto, Cathy, der Vliet, Jan, Knippenberg, Marlene, Greuter, Mascha J., Hilbers, Francisca W., Konijn, Tanja, Velde, Anje A., Nolte, Martijn A., Boeckxstaens, Guy E., Jonge, Wouter J., Mebius, Reina E.

“…Tertiary lymphoid tissue (TLT) is lymphoid tissue that forms in adult life as a result of chronic inflammation in a tissue or organ. TLT has been shown to form…”
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The SCFA butyrate stimulates the epithelial production of retinoic acid via inhibition of epithelial HDAC by Schilderink, Ronald, Verseijden, Caroline, Seppen, Jurgen, Muncan, Vanesa, van den Brink, Gijs R, Lambers, Tim T, van Tol, Eric A, de Jonge, Wouter J

“…In the intestinal mucosa, retinoic acid (RA) is a critical signaling molecule. RA is derived from dietary vitamin A (retinol) through conversion by aldehyde…”
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Adrenergic β2 receptor activation stimulates anti-inflammatory properties of dendritic cells in vitro by Nijhuis, Laurens E, Olivier, Brenda J, Dhawan, Shobit, Hilbers, Francisca W, Boon, Louis, Wolkers, Monika C, Samsom, Janneke N, de Jonge, Wouter J

“…Vagal nerve efferent activation has been shown to ameliorate the course of many inflammatory disease states. This neuro-modulatory effect has been suggested to…”
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The Progress of Intestinal Epithelial Models from Cell Lines to Gut-On-Chip by Rahman, Shafaque, Ghiboub, Mohammed, Donkers, Joanne M, van de Steeg, Evita, van Tol, Eric A F, Hakvoort, Theodorus B M, de Jonge, Wouter J

“…Over the past years, several preclinical in vitro and ex vivo models have been developed that helped to understand some of the critical aspects of intestinal…”
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Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4 by van der Mark, Vincent A., Ghiboub, Mohammed, Marsman, Casper, Zhao, Jing, van Dijk, Remco, Hiralall, Johan K., Ho-Mok, Kam S., Castricum, Zoë, de Jonge, Wouter J., Oude Elferink, Ronald P. J., Paulusma, Coen C.

“…P4-ATPases are lipid flippases that catalyze the transport of phospholipids to create membrane phospholipid asymmetry and to initiate the biogenesis of…”
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Nutritional Therapy to Modulate Tryptophan Metabolism and Aryl Hydrocarbon-Receptor Signaling Activation in Human Diseases by Ghiboub, Mohammed, Verburgt, Charlotte M, Sovran, Bruno, Benninga, Marc A, de Jonge, Wouter J, Van Limbergen, Johan E

“…The aryl hydrocarbon receptor (AhR) is a nuclear protein which, upon association with certain endogenous and exogenous ligands, translocates into the nucleus,…”
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Sympathetic Denervation Alters the Inflammatory Response of Resident Muscularis Macrophages upon Surgical Trauma and Ameliorates Postoperative Ileus in Mice by Mallesh, Shilpashree, Schneider, Reiner, Schneiker, Bianca, Lysson, Mariola, Efferz, Patrik, Lin, Eugene, de Jonge, Wouter J, Wehner, Sven

“…Interactions between the peripheral nervous system and resident macrophages (MMs) modulate intestinal homeostatic functions. Activation of β2-adrenergic…”
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Intestinal mast cells in gut inflammation and motility disturbances by De Winter, Benedicte Y., van den Wijngaard, Rene M., de Jonge, Wouter J.

“…Mast cells may be regarded as prototypes of innate immune cells that can be controlled by neuronal mediators. Their activation has been implicated in many…”
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Incisional hernia after surgical correction of abdominal congenital anomalies in infants: a systematic review with meta-analysis by Eeftinck Schattenkerk, Laurens D., Musters, Gijsbert D., Nijssen, David J., de Jonge, Wouter J., de Vries, Ralph, van Heurn, L. W. Ernest, Derikx, Joep PM

“…Incisional hernia (IH) in children could result in life-threatening complications, including incarceration and bowel strangulation. The incidence and risk…”
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Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis by Zweers, Serge J., Shiryaev, Alexey, Komuta, Mina, Vesterhus, Mette, Hov, Johannes R., Perugorria, María J., de Waart, D. Rudi, Chang, Jung-Chin, Tol, Shanna, te Velde, Anje A., de Jonge, Wouter J., Banales, Jesus M., Roskams, Tania, Beuers, Ulrich, Karlsen, Tom H., Jansen, Peter L., Schaap, Frank G.

“…Background & Aims To better understand the pathogenesis of primary sclerosing cholangitis, anti‐ and pro‐inflammatory factors were studied in bile. Methods…”
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Morphometric analysis of the splenic artery using contrast-enhanced computed tomography (CT) by Brinkman, David J., Troquay, Stephanie, de Jonge, Wouter J., Irwin, Eric D., Vervoordeldonk, Margriet J., Luyer, Misha D. P., Nederend, Joost

“…Purpose To evaluate the morphology and course of the splenic artery, which might impact the surgical implantation of systems that stimulate the nerves…”
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Nutritional Therapy Strategies in Pediatric Crohn's Disease by Verburgt, Charlotte M, Ghiboub, Mohammed, Benninga, Marc A, de Jonge, Wouter J, Van Limbergen, Johan E

“…The increase in incidences of pediatric Crohn's Disease (CD) worldwide has been strongly linked with dietary shifts towards a Westernized diet, ultimately…”
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HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages by Ghiboub, Mohammed, Zhao, Jing, Li Yim, Andrew Y F, Schilderink, Ronald, Verseijden, Caroline, van Hamersveld, Patricia H P, Duarte, Jose M, Hakvoort, Theodorus B M, Admiraal, Iris, Harker, Nicola R, Tough, David F, Henneman, Peter, de Winther, Menno P J, de Jonge, Wouter J

“…Histone deacetylases (HDACs) are a group of enzymes that control histone deacetylation and bear potential to direct expression of large gene sets. We…”
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