Search Results - "Jong In Yook"

New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites by Lee, Inhan, Ajay, Subramanian S, Yook, Jong In, Kim, Hyun Sil, Hong, Su Hyung, Kim, Nam Hee, Dhanasekaran, Saravana M, Chinnaiyan, Arul M, Athey, Brian D

“…MicroRNAs (miRNAs) are known to post-transcriptionally regulate target mRNAs through the 3'-UTR, which interacts mainly with the 5'-end of miRNA in animals…”
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Exploring the chemical space of protein–protein interaction inhibitors through machine learning by Choi, Jiwon, Yun, Jun Seop, Song, Hyeeun, Kim, Nam Hee, Kim, Hyun Sil, Yook, Jong In

“…Although protein–protein interactions (PPIs) have emerged as the basis of potential new therapeutic approaches, targeting intracellular PPIs with small…”
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Wnt-dependent Regulation of the E-cadherin Repressor Snail by Yook, Jong In, Li, Xiao-Yan, Ota, Ichiro, Fearon, Eric R., Weiss, Stephen J.

“…Down-regulation of E-cadherin marks the initiation of the epithelial-mesenchymal transition, a process exploited by invasive cancer cells. The zinc finger…”
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Quercetin and Quercitrin from Agrimonia pilosa Ledeb Inhibit the Migration and Invasion of Colon Cancer Cells through the JNK Signaling Pathway by Trinh, Nguyet-Tran, Nguyen, Thi Minh Ngoc, Yook, Jong-In, Ahn, Sang-Gun, Kim, Soo-A

“…Considering the high metastatic potential of colorectal cancer (CRC), the inhibition of metastasis is important for anti-CRC therapy. Ledeb ( ) is a perennial…”
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Lactate as a major epigenetic carbon source for histone acetylation via nuclear LDH metabolism by An, Yong Jin, Jo, Sihyang, Kim, Jin-Mo, Kim, Han Sun, Kim, Hyun Young, Jeon, Sang-Min, Han, Dawool, Yook, Jong In, Kang, Keon Wook, Park, Sunghyouk

“…Histone acetylation involves the transfer of two-carbon units to the nucleus that are embedded in low-concentration metabolites. We found that lactate, a…”
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Global analysis of gene expression profiles in the submandibular salivary gland of klotho knockout mice by Kwon, Sung‐Min, Kim, Soo‐A, Yoon, Jung‐Hoon, Yook, Jong‐In, Ahn, Sang‐Gun

“…Salivary dysfunction commonly occurs in many older adults and is considered a physiological phenomenon. However, the genetic changes in salivary glands during…”
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Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells by Nam, Woong, Tak, Jungae, Ryu, Ju-Kyoung, Jung, Mankil, Yook, Jong-In, Kim, Hyung-Jun, Cha, In-Ho

“…Background. Artemisinin is of special biological interest because of its outstanding antimalarial activity. Recently, it was reported that artemisinin has…”
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Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells by MASUI, TAKASHI, OTA, ICHIRO, YOOK, JONG-IN, MIKAMI, SHINJI, YANE, KATSUNARI, YAMANAKA, TOSHIAKI, HOSOI, HIROSHI

“…Head and neck squamous cell carcinoma (HNSCC) is known to have a poor prognosis. The resistance to treatment and distant metastasis are important clinical…”
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Therapeutic implications of cancer epithelial-mesenchymal transition (EMT) by Cho, Eunae Sandra, Kang, Hee Eun, Kim, Nam Hee, Yook, Jong In

“…The epithelial-mesenchymal transition (EMT) comprises an essential biological process involving cancer progression as well as initiation. While the EMT has…”
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Dishevelling Wnt and Hippo by Kim, Nam Hee, Lee, Yoonmi, Yook, Jong In

“…As highly conserved signaling cascades of multicellular organisms, Wnt and Hippo pathways control a wide range of cellular activities, including cell adhesion,…”
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Glycogen Synthase Kinase-3 Interaction Domain Enhances Phosphorylation of SARS-CoV-2 Nucleocapsid Protein by Jun Seop, Yun, Hyeeun, Song, Nam Hee, Kim, So Young, Cha, Kyu Ho, Hwang, Jae Eun, Lee, Cheol-Hee, Jeong, Sang Hyun, Song, Seonghun, Kim, Eunae Sandra, Cho, Hyun Sil, Kim, Jong In, Yook

“…A structural protein of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), nucleocapsid (N) protein is phosphorylated by glycogen synthase kinase…”
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Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality by Choi, Hojun, Kim, Youngeun, Mirzaaghasi, Amin, Heo, Jaenyoung, Kim, Yu Na, Shin, Ju Hye, Kim, Seonghun, Kim, Nam Hee, Cho, Eunae Sandra, In Yook, Jong, Yoo, Tae-Hyun, Song, Eunjoo, Kim, Pilhan, Shin, Eui-Cheol, Chung, Kyungsoo, Choi, Kyungsun, Choi, Chulhee

“…As extracellular vesicles that play an active role in intercellular communication by transferring cellular materials to recipient cells, exosomes offer great…”
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Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress by Kim, Nam Hee, Cha, Yong Hoon, Lee, Jueun, Lee, Seon-Hyeong, Yang, Ji Hye, Yun, Jun Seop, Cho, Eunae Sandra, Zhang, Xianglan, Nam, Miso, Kim, Nami, Yuk, Young-Su, Cha, So Young, Lee, Yoonmi, Ryu, Joo Kyung, Park, Sunghyouk, Cheong, Jae-Ho, Kang, Sang Won, Kim, Soo-Youl, Hwang, Geum-Sook, Yook, Jong In, Kim, Hyun Sil

“…Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial–mesenchymal transition (EMT) is not…”
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Snail-induced EMT promotes cancer stem cell-like properties in head and neck cancer cells by OTA, ICHIRO, MASUI, TAKASHI, KURIHARA, MIYAKO, YOOK, JONG-IN, MIKAMI, SHINJI, KIMURA, TAKAHIRO, SHIMADA, KEIJI, KONISHI, NOBORU, YANE, KATSUNARI, YAMANAKA, TOSHIAKI, KITAHARA, TADASHI

“…Epithelial-mesenchymal transition (EMT) is a key process involved in the invasion and metastasis of cancer cells. Furthermore, EMT can induce a cancer stem…”
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TGF-β Pathway in Salivary Gland Fibrosis by Zhang, Xianglan, Yun, Jun Seop, Han, Dawool, Yook, Jong In, Kim, Hyun Sil, Cho, Eunae Sandra

“…Fibrosis is presented in various physiologic and pathologic conditions of the salivary gland. Transforming growth factor beta (TGF-β) pathway has a pivotal…”
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The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy by Cho, Eunae Sandra, Cha, Yong Hoon, Kim, Hyun Sil, Kim, Nam Hee, Yook, Jong In

“…During cancer progression, cancer cells are repeatedly exposed to metabolic stress conditions in a resource-limited environment which they must escape…”
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A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition by Kim, Nam Hee, Kim, Hyun Sil, Li, Xiao-Yan, Lee, Inhan, Choi, Hyung-Seok, Kang, Shi Eun, Cha, So Young, Ryu, Joo Kyung, Yoon, Dojun, Fearon, Eric R, Rowe, R Grant, Lee, Sanghyuk, Maher, Christopher A, Weiss, Stephen J, Yook, Jong In

“…Snail1 is a zinc finger transcriptional repressor whose pathological expression has been linked to cancer cell epithelial-mesenchymal transition (EMT) programs…”
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Molecular recognition of proteolytic activity in metastatic cancer cells using fluorogenic gold nanoprobes by Hong, Yoochan, Ku, Minhee, Heo, Dan, Hwang, Seungyeon, Lee, Eugene, Park, Joseph, Choi, Jihye, Jung Lee, Hyeon, Seo, Miran, Jig Lee, Eun, In Yook, Jong, Haam, Seungjoo, Huh, Yong-Min, Sung Yoon, Dae, Suh, Jin-Suck, Yang, Jaemoon

“…We describe the development of biomarker-sensitive nanoprobes based on nanoparticle surface energy transfer (NSET) effect that enabling recognition of the…”
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Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells by Lee, Eun Ju, Kim, Jin, Lee, Seoung Ae, Kim, Eun Jung, Chun, Yong Chan, Ryu, Mi Heon, Yook, Jong In

“…Since genetic abnormalities of human cancer are greatly geographically dependent, cultural and environmental backgrounds are thought to be closely related to…”
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Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner by Lee, Yoonmi, Kim, Nam Hee, Cho, Eunae Sandra, Yang, Ji Hye, Cha, Yong Hoon, Kang, Hee Eun, Yun, Jun Seop, Cho, Sue Bean, Lee, Seon-Hyeong, Paclikova, Petra, Radaszkiewicz, Tomasz W., Bryja, Vitezslav, Kang, Chi Gu, Yuk, Young Soo, Cha, So Young, Kim, Soo-Youl, Kim, Hyun Sil, Yook, Jong In

“…Phosphorylation-dependent YAP translocation is a well-known intracellular mechanism of the Hippo pathway; however, the molecular effectors governing YAP…”
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