Search Results - "Jong, Yong S."

Biologically erodable microspheres as potential oral drug delivery systems by Mathiowitz, Edith, Jacob, Jules S, Jong, Yong S, Carino, Gerardo P, Chickering, Donald E, Chaturvedi, Pravin, Santos, Camilla A, Vijayaraghavan, Kavita, Montgomery, Sean, Bassett, Michael, Morrell, Craig

“…Biologically adhesive delivery systems offer important advantages over conventional drug delivery systems. Here we show that engineered polymer microspheres…”
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Cancer immunotherapy with interleukin 12 and granulocyte-macrophage colony-stimulating factor-encapsulated microspheres: Coinduction of innate and adaptive antitumor immunity and cure of disseminated disease by HILL, Hank C, CONWAY, Thomas F, SABEL, Michael S, JONG, Yong S, MATHIOWITZ, Edith, BANKERT, Richard B, EGILMEZ, Nejat K

“…Tumor cells, injected s.c., were maintained until spontaneous metastases to the lungs were established in all of the mice. Mice were then treated with a single…”
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IL-12 + GM-CSF microsphere therapy induces eradication of advanced spontaneous tumors in her-2/neu transgenic mice but fails to achieve long-term cure due to the inability to maintain effector T-cell activity by NAIR, Raji E, JONG, Yong S, JONES, Stacy A, SHARMA, Atima, MATHIOWITZ, Edith, EGILMEZ, Nejat K

“…A single intratumoral injection of interleukin-12 and granulocyte-macrophage colony-stimulating factor-encapsulated microspheres induced the regression of…”
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In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres : Induction of tumor regression and potent antitumor immunity by EGILMEZ, N. K, JONG, Y. S, SABEL, M. S, JACOB, J. S, MATHIOWITZ, E, BANKERT, R. B

“…An alternative technology for the local and sustained delivery of cytokines to tumors for cancer immunotherapy was evaluated and shown here to induce tumor…”
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Novel desiccants based on designed polymeric blends by Mathiowitz, Edith, Jacob, Jules S., Jong, Yong S., Hekal, Thab M., Spano, William, Guemonprez, Rene, Klibanov, Alexander M., Langer, Robert

“…We describe a novel concept for the preparation of desiccants based on polymeric blends. A hydrophilic channeling agent (e.g., PEG) is blended with a…”
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Neoadjuvant therapy with interleukin-12-loaded polylactic acid microspheres reduces local recurrence and distant metastases by Sabel, Michael S., Hill, Hank, Jong, Yong S., Mathiowitz, Edith, Bankert, Richard B., Egilmez, Nejat K.

“…We previously demonstrated that the intratumoral injection of biodegradable polylactic acid microspheres that were loaded with interleukin (IL)-12 can induce a…”
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Tumor vaccination with cytokine-encapsulated microspheres by Egilmez, Nejat K, Jong, Yong S, Mathiowitz, Edith, Bankert, Richard B

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Controlled release of plasmid DNA by Jong, Yong S, Jacob, Jules S, Yip, Kay-Pong, Gardner, Graham, Seitelman, Ellen, Whitney, Marsha, Montgomery, Sean, Mathiowitz, Edith

“…Very large molecular weight reporter plasmids (pCMV- βgal, pSV- βgal) and lower molecular weight (herring sperm) DNA were encapsulated in polyethylene vinyl…”
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Human inflammatory cells within the tumor microenvironment of lung tumor xenografts mediate tumor growth suppression in situ that depends on and is augmented by interleukin-12 by SUGIYAMA, Yasuyuki, KATO, Motohisa, CHEN, Fang-An, WILLIAMS, Scott S, KAWAGUCHI, Yoshihiro, MIYA, Kiichi, JONG, Yong S, MATHIOWITZ, Edith, EGILMEZ, Nejat K, BANKERT, Richard B

“…The human tumor microenvironment includes a mixture of tumor cells, inflammatory cells, fibroblasts, and endothelial cells, all of which are tethered to an…”
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Regression of Established Autochthonous Mammary Tumors and Induction of Systemic Anti-Tumor T- and B-Cell Immunity in HER-2/NEU Transgenic Mice after Treatment with IL-12 and GM-CSF-Encapsulated Microspheres by Nair, Easwari R, Jong, Yong S, Egilmez, Nejat K

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In vitro and in vivo degradation of double-walled polymer microspheres by Pekarek, Kathleen J., Dyrud, Martinus J., Ferrer, Kathy, Jong, Yong S., Mathiowitz, Edith

“…By exploiting the phenomenon of phase separation, double-walled microspheres consisting of a core of one polymer surrounded by a coating of a second polymer…”
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Cytokine immunotherapy of cancer with controlled release biodegradable microspheres in a human tumor xenograft/SCID mouse model by EGILMEZ, N. K, JONG, Y. S, IWANUMA, Y, JACOB, J. S, SANTOS, C. A, CHEN, F.-A, MATHIOWITZ, E, BANKERT, R. B

“…A novel biodegradable poly(lactic acid) microsphere formulation was evaluated for in vivo cytokine immunotherapy of cancer in a human tumor xenograft/ severe…”
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Cytokines delivered by biodegradable microspheres promote effective suppression of human tumors by human peripheral blood lymphocytes in the SCID-winn model by EGILMEZ, N. K, JONG, Y. S, HESS, S. D, JACOB, J. S, MATHIOWITZ, E, BANKERT, R. B

“…A new technology for the local and sustained delivery of immunostimulatory molecules to the tumor environment for cancer immunotherapy was evaluated. The…”
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Study on Stopping Ability of a Ship Equipped with Azimuth Propeller by Park, Jong-Yong, Oh, Pilgun, Kim, Taejin, Lee, Jun-Ho

“…An azimuth propeller can generate thrust in all directions by rotating its housing with an electric motor. An azimuth propeller can be operated using several…”
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Development of automatic gain-tuning algorithm for heading control using free-running test data by Jung-Hyeon Kim, Su-Rim Kim, Hyun-Jae Jo, Chan Young Yeo, Dong Jin Yeo, Kunhang Yun, Jeonghong Park, Jong-Yong Park

“…This study proposes an automatic gain-tuning algorithm for ships. The proposed algorithm is designed to tune the gains of the ship controller automatically,…”
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Design of an adaptive backstepping controller for auto-berthing a cruise ship under wind loads by Park, Jong-Yong, Kim, Nakwan

“…The auto-berthing of a ship requires excellent control for safe accomplishment. Crabbing, which is the pure sway motion of a ship without surge velocity, can…”
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Experimental study on hydrodynamic coefficients for high-incidence-angle maneuver of a submarine by Park, Jong-Yong, Kim, Nakwan, Shin, Yong-Ku

“…Snap rolling during hard turning and instability during emergency rising are important features of submarine operation. Hydrodynamics modeling using a high…”
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잠수함의 종동요각 한계예측 알고리즘 설계 by 박종용(Jong-Yong Park), 김낙완(Nakwan Kim), 신용구(Yong-Ku Shin)

“…An envelope protection system is a control system that allows a submarine to operate freely using its own operational envelope without exceeding the structural…”
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적응제어기법을 이용한 수면근처에서 운항하는 몰수체의 심도제어기 설계 by 박종용(Jong-Yong Park), 김낙완(Nakwan Kim), 윤현규(Hyeon Kyu Yoon), 김수용(Su Yong Kim), 조현진(Hyeonjin Cho)

“…A submerged body moving near the free surface needs to maintain its attitude and position to accomplish missions. It is necessary to validate the performance…”
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선박 자동접안을 위한 순수 횡 이동 모델링 및 제어기 설계 by 박종용(Jong-Yong Park), 김낙완(Nakwan Kim)

“…Crabbing motion is the pure sway motion of a ship without surge velocity. Thus, it can be applied to a berthing operation. Crabbing motion is induced by a…”
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