Search Results - "Jong, Victor L"
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Transcriptome assists prognosis of disease severity in respiratory syncytial virus infected infants
Published in Scientific reports (11-11-2016)“…Respiratory syncytial virus (RSV) causes infections that range from common cold to severe lower respiratory tract infection requiring high-level medical care…”
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Meta-analysis approach as a gene selection method in class prediction: does it improve model performance? A case study in acute myeloid leukemia
Published in BMC bioinformatics (11-04-2017)“…Aggregating gene expression data across experiments via meta-analysis is expected to increase the precision of the effect estimates and to increase the…”
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Prenatal maternal distress and immune cell epigenetic profiles at 3‐months of age
Published in Developmental psychobiology (01-07-2021)“…Background Prenatal maternal distress predicts altered offspring immune outcomes, potentially via altered epigenetics. The role of different kinds of prenatal…”
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An Application of Sequential Meta-Analysis to Gene Expression Studies
Published in Cancer informatics (01-01-2015)“…Most of the discoveries from gene expression data are driven by a study claiming an optimal subset of genes that play a key role in a specific disease…”
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5
Proinflammatory Cytokine Responses in Extra-Respiratory Tissues During Severe Influenza
Published in The Journal of infectious diseases (17-10-2017)“…Severe influenza is often associated with disease manifestations outside the respiratory tract. While proinflammatory cytokines can be detected in the lungs…”
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Identification of differentially expressed peptides in high-throughput proteomics data
Published in Briefings in bioinformatics (28-09-2018)“…Abstract With the advent of high-throughput proteomics, the type and amount of data pose a significant challenge to statistical approaches used to validate…”
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Factors affecting the accuracy of a class prediction model in gene expression data
Published in BMC bioinformatics (21-06-2015)“…Class prediction models have been shown to have varying performances in clinical gene expression datasets. Previous evaluation studies, mostly done in the…”
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Selecting a classification function for class prediction with gene expression data
Published in Bioinformatics (15-06-2016)“…Class predicting with gene expression is widely used to generate diagnostic and/or prognostic models. The literature reveals that classification functions…”
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Host proteome correlates of vaccine-mediated enhanced disease in a mouse model of respiratory syncytial virus infection
Published in Journal of virology (01-05-2015)“…Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in infants. Despite over 50 years of research, to date no safe and…”
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Exploring homogeneity of correlation structures of gene expression datasets within and between etiological disease categories
Published in Statistical applications in genetics and molecular biology (01-12-2014)“…The literature shows that classifiers perform differently across datasets and that correlations within datasets affect the performance of classifiers. The…”
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11
An Application of Sequential Meta-Analysis to Gene Expression Studies
Published in Cancer informatics (01-01-2015)“…Most of the discoveries from gene expression data are driven by a study claiming an optimal subset of genes that play a key role in a specific disease…”
Get full text
Journal Article