Search Results - "Jong, S. H."
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1
DNA hypermethylation in gastric cancer
Published in Alimentary pharmacology & therapeutics (01-07-2004)“…Summary Background : Transcriptional silencing of tumour suppressor genes by DNA hypermethylation plays a crucial role in the progression of gastric cancer…”
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2
Prevalence of nodal metastases in the individual lymph node stations for different T-stages in gastric cancer: a systematic review
Published in Updates in surgery (01-02-2023)“…Background Gastrectomy with lymph node dissection is the cornerstone of curative treatment of gastric cancer. Extent of lymphadenectomy may differ depending on…”
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3
Polymeric formula has direct anti-inflammatory effects on enterocytes in an in vitro model of intestinal inflammation
Published in Digestive diseases and sciences (01-09-2007)“…Exclusive enteral nutrition using polymeric formula (PF) is a well-established therapeutic option for active Crohn's disease; however, its mechanisms of action…”
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4
Phosphine-Catalyzed Sequential Michael Addition between α-Aminonitriles and Methyl Acrylate for Cyclization: Synthesis of N-Aryl-Substituted Pyrrolidines
Published in Russian journal of organic chemistry (01-12-2020)“…N -Aryl-substituted pyrrolidine derivatives were synthesized via tributylphosphine-catalyzed sequential Michael addition of α-aminonitriles and methyl acrylate…”
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5
Up‐regulation of human telomerase catalytic subunit during gastric carcinogenesis
Published in Cancer (15-08-1999)“…BACKGROUND Telomerase activation is thought to be essential for the stabilization of telomere length, through which immortalization and oncogenesis are…”
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6
Genetic integrity of transforming growth factor β (TGF‐β) receptors in cervical carcinoma cell lines: loss of growth sensitivity but conserved transcriptional response to TGF‐β
Published in International journal of cancer (12-08-1998)“…Transforming growth factor β (TGF‐β) exerts an inhibitory effect on the growth of most epithelial cell types, and the loss of responsiveness to this growth…”
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7
Polymeric Formula Has Direct Anti-Inflammatory Effects on Enterocytes in an in VitroModel of Intestinal Inflammation
Published in Digestive diseases and sciences (01-09-2007)“…Exclusive enteral nutrition using polymeric formula (PF) is a well-established therapeutic option for active Crohn's disease; however, its mechanisms of action…”
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8
Rapid induction of p21WAF1 but delayed down-regulation of Cdc25A in the TGF-β-induced cell cycle arrest of gastric carcinoma cells
Published in British journal of cancer (01-06-1999)“…Transforming growth factor-beta (TGF-beta) is a multifunctional polypeptide that inhibits cellular proliferation in most epithelial cells. cdk4 and several…”
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9
Fecal S100A12: A novel noninvasive marker in children with Crohn's disease
Published in Inflammatory bowel diseases (01-07-2006)“…Background: The calcium‐binding protein S100A12 is related to calprotectin, a protein shown to be a useful marker of gut inflammation. S100A12 levels are…”
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10
Telomerase activity in lung cancer cell lines and tissues
Published in Lung cancer (Amsterdam, Netherlands) (01-08-1998)“…Using TRAP assay, we studied the activity of the telomerase in the lung cancer cell lines, and lung cancer and normal tissues in which expression appears to be…”
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11
AKAP12 Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity
Published in Oncogene (16-09-2004)“…AKAP12/Gravin, one of the A-kinase anchoring proteins (AKAPs), functions as a kinase scaffold protein and as a dynamic regulator of the beta2-adrenergic…”
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12
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells
Published in Oncogene (19-06-2003)“…DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma. However, little is known about the genetic status and the expression of…”
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13
Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells
Published in Cancer research (Chicago, Ill.) (01-06-2001)“…It has been well established that overexpression of Cyclooxygenase-2 (Cox-2) in epithelial cells inhibits apoptosis and increases the invasiveness of malignant…”
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14
Aberrant methylation of integrin alpha 4 gene in human gastric cancer cells
Published in Oncogene (22-04-2004)“…Integrins are adhesion receptors that mediate both cell-extracellular matrix and cell-cell interactions. It has also been reported that the loss of integrin…”
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15
Characteristics of DNA-Binding Activity of Human Cytomegalovirus ppUL44
Published in MICROBIOLOGY and IMMUNOLOGY (01-01-2000)“…Human cytomegalovirus (HCMV)-specific monoclonal antibody, SCMVM34, recognizes the early antigen encoded by UL44 of HCMV. This antigen is confined to the…”
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16
Methylation of specific CpG sites in the promoter region could significantly down-regulate p16(INK4a) expression in gastric adenocarcinoma
Published in International journal of cancer (15-07-2000)“…Silencing of p16(INK4a) by methylation of the CpG islands in the promoter region has been found to be an alternative mechanism of inactivation in several…”
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17
Caspase-mediated Cdk2 activation is a critical step to execute transforming growth factor- beta 1-induced apoptosis in human gastric cancer cells
Published in Oncogene (08-03-2001)“…Although TGF- beta 1, a growth inhibitor, is known to also induce apoptosis, the molecular mechanism of this apoptosis is largely undefined. Here, we identify…”
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Transcriptional inactivation of the tissue inhibitor of metalloproteinase‐3 gene by dna hypermethylation of the 5'‐CpG island in human gastric cancer cell lines
Published in International journal of cancer (01-06-2000)“…The tissue inhibitor of metalloproteinase‐3 (TIMP‐3), a recently cloned member of TIMP gene family, has been implicated in the negative regulation of tumor…”
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19
A novel ginseng saponin metabolite induces apoptosis and down-regulates fibroblast growth factor receptor 3 in myeloma cells
Published in International journal of oncology (01-10-2003)“…Ginseng (the root of Panax ginseng C.A. Meyer, Araliaceae) has been used as a crude drug taken orally for preventive and therapeutic purposes in Asian…”
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20
Sensitivity of various visualization methods for peroxidase and alkaline phosphatase activity in immunoenzyme histochemistry
Published in The Histochemical journal (01-10-1985)“…Various chromogen protocols for visualizing peroxidase and alkaline phosphatase activity in immunoenzyme histochemistry were compared with respect to their…”
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